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| 1 | Race and survival after cardiac arrest显示文摘 | Dezfulian C Cobas M Pretto E | 2010 | JAMA2010，303，2： | 1 |
| 2 | Relevance of Akt phosphorylation in cell transformation induced by Jaagsiekte sheep retrovirus 显示文摘 | Zavala G Pretto C Chow Y H | 2003 | Virology2003，312，1： | 1 |
| 3 | Relevance of Akt phosphorylation in cell transformation induced by Jaagsiekte sheep retrovirus显示文摘 | Zavala G Pretto C Chow YHJ | 2003 | Virology2003，312，1： | 1 |
| 4 | Commercial formulation containing quinclorac and metsulfuron-methyl herbicides inhibit acetylcholinesterase and induce biochemical alterations in tissues of Leporinus obtusidens显示文摘 | Pretto A Loro V L Menezes C | 2011 | Ecotoxicology and Environmental Safety2011，74，3： | 1 |
| 5 | Histological findings of experimental Streptococcus agalactiae infection in Nile tilapias(Oreochromis niloticus)显示文摘 | Inocente Filho C Müller E E Pretto G L G | 2009 | Brazilian Journal of Veterinary Pathology2009，2，1： | 1 |
| 6 | Sublethal zine and copper exposure affect acetylcholinesterase activity and accumulation in different tissues of Leporinus obtusidens 显示文摘 | Gioda C R Loro V L Pretto A | 2013 | Bull Environ Contam Toxicol2013，90，1： | 1 |
| 7 | Commercial formulation containing quinelorac and metsulfuron - methyl herbicides inhibit aeetylcholinesterase and induce biochemical alterations in tissues of Leporinus obtusiderts 显示文摘 | Pretto A Loro V L Menezes C | 2011 | Ecotoxicology and Environmental Safety2011，74，3： | 1 |
| 8 | Commercial formulationcontaining quinclorac and metsulfuron-methyl herbicides inhibit acety-lcholinesterase and induce biochemical alterations in tissues of Leporinusobtusidens显示文摘 | PRETTO A LORO V L MENEZES C | 2011 | Ecotoxicology Environmental Safety2011，74，3： | 1 |
| 9 | Histological findings of experimental Streptococcus agalactiae infection in Nile tilapias (Oreochromis niloticus)显示文摘 | Inocente F C M/iller E E Pretto G L G | 2009 | Brazilian Journal of Veterinary Pathology2009，2，1： | 1 |
| 10 | Relevance of Akt phosphorylation in cell transformation induced by jaag- siekte sheep retrovirus显示文摘 | ZAVALA G PRETTO C CHOW Y H | 2003 | Virology2003，312，95： | 1 |
| 11 | Intranuclear inclusions in a fragile X mosaic male显示文摘Lack of the fragile X mental retardation protein leads to Fragile X syndrome(FXS)while increased levels of FMR1 mRNA,as those observed in premutation carriers can lead to Fragile X-associated tremor ataxia syndrome(FXTAS).Until recently,FXTAS had been observed only in carriers of an FMR1 premutation(55–200 CGG repeats);however the disorder has now been described in individuals carriers of an intermediate allele(45–54 CGG repeats)as well as in a subject with a full mutation with mosaicism.Here,we report on molecular and clinical data of a male FMR1 mosaic individual with full and premutation alleles.Molecular analysis of FMR1 and FMRP expression in this subject is consistent with a FXS phenotype.We observed reduced expression of FMRP in both peripheral blood and brain leading to the FXS diagnosis.In addition,a dramatic 90%depletion of both FMR1 mRNA and FMRP levels was observed in the blood,as normally observed in FXS cases,and an even greater depletion in the brain.A clinical report of this patient,at age 71,described neurodegenerative signs of parkinsonism that were likely,in retrospect,part of a FXTAS scenario as post-mortem examination shows the presence of intranuclear inclusions,the hallmark pathology of FXTAS.The findings presented in this study indicate co-morbidity for both FXS and FXTAS in this individual carrying both full and premutation FMR1 alleles.In addition,based on symptoms and pathological and molecular evidence,this report suggests the need to redefine the diagnostic criteria of FXTAS. | Dalyir I Pretto Michael R Hunsaker Christopher L Cunningham Claudia M Greco Randi J Hagerman Stephen C Noctor Deborah A Hall Paul J Hagerman Flora Tassone | 2013 | Translational Neurodegeneration2013，2，1： | 0 |
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