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您的检索式：作者名="Prem L.Bhalla"
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| 1 | Biological Parts for Engineering Abiotic Stress Tolerance in Plants显示文摘It is vital to ramp up crop production dramatically by 2050 due to the increasing global population and demand for food.However, with the climate change projections showing that droughts and heatwaves becoming common in much of the globe,there is a severe threat of a sharp decline in crop yields. Thus, developing crop varieties with inbuilt genetic tolerance toenvironmental stresses is urgently needed. Selective breeding based on genetic diversity is not keeping up with the growingdemand for food and feed. However, the emergence of contemporary plant genetic engineering, genome-editing, and syntheticbiology offer precise tools for developing crops that can sustain productivity under stress conditions. Here, we summarize thesystems biology-level understanding of regulatory pathways involved in perception, signalling, and protective processesactivated in response to unfavourable environmental conditions. The potential role of noncoding RNAs in the regulation ofabiotic stress responses has also been highlighted. Further, examples of imparting abiotic stress tolerance by geneticengineering are discussed. Additionally, we provide perspectives on the rational design of abiotic stress tolerance throughsynthetic biology and list various bioparts that can be used to design synthetic gene circuits whose stress-protective functionscan be switched on/off in response to environmental cues. | Neeta Lohani Mohan B.Singh Prem L.Bhalla | 2022 | BioDesign Research2022，，1： | 0 |
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