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| 1 | Resection of the uncinate process of the pancreas due to a ganglioneuroma显示文摘A 33-year-old woman who presented with epigastric discomfort and diarrhea underwent an abdominal ultrasound(US).This investigation and subsequent contrastenhanced computed tomography,magnetic resonance imaging and endoscopic US with fine needle aspiration (FNA)revealed a 40 mm well-circumscribed mass in the uncinate process of the pancreas.Findings were suggestive of a mucinous or solid-cystic pseudopapillary tumor of the pancreas,although other lesions such as a nonfunctioning neuroendocrine tumor could not be ruled out.FNA samples were negative for malignant cells,but of limited value due to poor cellularity.It was decided to surgically remove the tumor because malignancy could not be discounted.Multiple intraoperative biopsies were suggestive of mesenchymal tumor and consequently a conservative resection(uncinatectomy)was performed. The postoperative course was uneventful.The definitive diagnosis was ganglioneuroma.Immunocytochemistry showed positive staining with vimentin,S-100 protein, neurofilament and neuron-specific enolase.Ganglioneuroma is a rare benign tumor that can also present as a pancreatic tumor.Uncinatectomy is feasible,safe and a good surgical technique for the treatment of nonmalignant tumors located in the uncinate process of the pancreas. | Ignasi Poves Fernando Burdío Mar Iglesias María de los ángeles Martínez-Serrano Guadalupe Aguilar Luís Grande | 2009 | World Journal of Gastroenterology2009，15，34： | 3 |
| 2 | Laparoscopic surgery in the elderly patient显示文摘 | Bàllesta López C Cid JA Poves I | 2003 | Surg Endosc2003，17，2： | 1 |
| 3 | Multiplexed Biosensing Diagnostic Platforms Detecting Autoantibodies to Tumor-Associated Antigens from Exosomes Released by CRC Cells and Tissue Samples Showed High Diagnostic Ability for Colorectal Cancer显示文摘Colorectal cancer(CRC)is the second leading cause of cancer-related death worldwide.The five-year survival rate of CRC patients depends on the stage at diagnosis,being higher than 80%when CRC is diagnosed in the early stages but lower than 10%when CRC is diagnosed in advanced stages.Autoantibodies against specific CRC autoantigens(tumor-associated antigens(TAAs))in the sera of patients have been widely demonstrated to aid in early diagnosis.Thus,we herein aim to identify autoantigens target of autoantibodies specific to CRC that possess a significant ability to discriminate between CRC patients and healthy individuals by means of liquid biopsy.To that end,we examined the protein content of the exosomes released by five CRC cell lines and tissue samples from CRC patients by means of immunoprecipitation coupled with mass spectrometry analysis.A total of 103 proteins were identified as potential autoantigens specific to CRC.After bioinformatics and meta-analysis,we selected 15 proteins that are more likely to be actual CRC autoantigens in order to evaluate their role in CRC prognosis by Western blot(WB)and immunohistochemistry(IHC).We found dysregulation at the protein level for 11 of these proteins in both tissue and plasma exosome samples from patients,along with an association of nine of these proteins with CRC prognosis.After validation,all but one showed a statistically significant high diagnostic ability to distinguish CRC patients and individuals with premalignant lesions from healthy individuals,either by luminescence Halotag-based beads,or by a multiplexed biosensing platform involving the use of magnetic microcarriers as solid support modified with covalently immobilized Halotag fusion proteins constructed for CRC detection.Taken together,our results highlight the usefulness of the approach defined here to identify the TAAs specific to chronic diseases;they also demonstrate that the measurement of autoantibody levels in plasma against the TAAs identified here could be integrated into a point-of-care(POC)device for CRC detection with high diagnostic ability. | Ana Montero-Calle Itziar Aranguren-Abeigon María Garranzo-Asensio Carmen Poves María Jesús Fernández-Aceñero Javier Martínez-Useros Rodrigo Sanz Jana Dziaková Javier Rodriguez-Cobos Guillermo Solís-Fernández Eloy Povedano Maria Gamella Rebeca Magnolia Torrente-Rodríguez Miren Alonso-Navarro Vivian de los Ríos J.Ignacio Casal Gemma Domínguez Ana Guzman-Aranguez Alberto Peláez-García JoséManuel Pingarrón Susana Campuzano Rodrigo Barderas | 2021 | Engineering2021，7，10： | 1 |
| 4 | Laparoscopic surgery in the elderly patient显示文摘 | Ballesta Lopez C Cid JA Poves I | 2003 | Surg Endose2003，17，： | 1 |
| 5 | Biodiesel from sunflower oil by using activated calcium oxide显示文摘 | Granados M L Poves M D Z Alonso D M | 2007 | Applied Ca talysis BEnvironmental2007，73，34： | 1 |
| 6 | Biodiesel from sunflower oil by using activated cakium oxide显示文摘 | LOPEZ GRANADOS M ZAFRA POVES M D MARTIN ALONSO D MARISCAL R CABELLO GALISTEO F MORENO-TOST R SANTAMARIA J FIERRO J L G | | 0，，： | 1 |
| 7 | Laparoscopy in acute biliary pancreatitis 显示文摘 | Ballesta Lopez CV Rnggiero Poves I | 2001 | Panminerva Med2001，43，4： | 1 |
| 8 | Results of Treatment in Severe Acute Pancreatitis显示文摘 | POVES I FABREGAT J BIONDO S | 2000 | Rev Esp Enferm Dig2000，92，9： | 1 |
| 9 | Robust chaos in neural networks显示文摘 | POTA POVE A KALIM | 2000 | Physics Letters A2000，277，6： | 1 |
| 10 | Biodiesel from sunflower oil by using activated calcium oxide显示文摘 | Granados M L Poves M D Z Alonso D M | 2007 | Applied catalysis B: Environmental2007，73，： | 1 |
| 11 | Shell Model Studies of the Double Beta Decays of 76Ge, 82Se and 136Xe 显示文摘 | Caurier E Nowacki F Poves A | 1996 | Phys Rev Lett1996，77，10： | 1 |
| 12 | Spatial Pulse Position Modula- tion for Optical Communications 显示文摘 | POPOOLA W O POVES E HASS H | 2012 | Lightwave Technology2012，30，18： | 1 |
| 13 | Biodiesel from sunflower oil by using activated calcium oxide显示文摘 | Granados M L Poves M D Z Alonso D M | 2007 | Applied Catalysis B-Environmental2007，73，34： | 1 |
| 14 | Biodiesel from sunflower oil by using activated calcium oxide 显示文摘 | GRANADOS M L POVES M D Z ALONSO D M | 2007 | Applied Catalysis B : Environmental2007，73，： | 1 |
| 15 | Acyanotic levoversion in situs inversus显示文摘 | Attie F Malpartid OF Poved JJ | 1973 | Chest1973，64，5： | 1 |
| 16 | Missing and Quenched Gamow-Teller Strength 显示文摘 | Caurier E Poves A Zuker A P | 1995 | Phys Rev Lett1995，74，9： | 1 |
| 17 | Cup-to-disk ratio asymmetry: diagnostic value in glaucoma显示文摘 | Polo Llorens V Larrosa Poves J M Pablo Julvez L E | 2002 | Arch Soc Esp Oftalmol2002，77，1： | 1 |
| 18 | Full pf Shell Study of A=47 and A=49 Nuclei 显示文摘 | Martinez-Pinedo G Zuker A P Poves A | 1997 | Phys Rev1997，55，1： | 1 |
| 19 | Laparoscopic snidery in the eldedy patient 显示文摘 | Ballesta Lopez C Cid JA Poves I | 2003 | Sui^ Enclose2003，17，： | 1 |
| 20 | Laparoscopy in acute biliary pancreatitis显示文摘 | Ballesta Lopez C Ruggiero R Poves I et a1 | 2001 | Panminerva Med2001，43，4： | 1 |
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