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| 1 | Metastatic pattern in esophageal and gastric cancer:Influenced by site and histology显示文摘BACKGROUND Detailed information on metastatic patterns in of patients with esophageal and gastric cancer is limited.Early recognition of metastases is important to avoid futile locoregional treatments.Furthermore,knowledge on metastatic patterns is necessary for further development of personalized treatment modalities.AIM To gain insight into the metastatic pattern of gastroesophageal cancer.METHODS A nationwide retrospective autopsy study of 3876 patients with adenocarcinoma(AC)or squamous cell carcinoma(SCC)of the esophagus or stomach between 1990 and 2017 was performed.Only patient with metastases were included for analysis.The metastatic pattern was analyzed according to the primary tumor location and histological subtype.RESULTS Metastatic disease was found in 268 esophageal and 331 gastric cancer patients.In esophageal cancer,the most common metastatic locations were liver(56%),distant lymph nodes(53%)and lung(50%).Esophageal AC showed more frequently metastases to the peritoneum and bone compared with esophageal SCC.In gastric cancer,the most common metastatic locations were distant lymph nodes(56%),liver(53%)and peritoneum(51%).Intestinal-type AC of the stomach showed metastases to the liver more frequently,whereas metastases to the bone,female reproductive organs and colorectum were observed more frequently in diffuse-type gastric AC.CONCLUSION This study showed differences in metastatic patterns of patients with esophageal and gastric cancer according to the primary tumor location and histological subtype. | Moniek HP Verstegen Mitchell Harker Carlijn van de Water Jolanda van Dieren Niek Hugen Iris D Nagtegaal Camiel Rosman Rachel S van der Post | 2020 | World Journal of Gastroenterology2020，26，39： | 9 |
| 2 | Application of auction as a price mechanism for the interchange of electric power显示文摘 | Post D L Coppinger S S Sheble G B | 1995 | IEEE Transactions on Power System1995，10，3： | 2 |
| 3 | Application of auction as a pricing mechanism for the interchange of electric power 显示文摘 | Post D L Coppinger S S Sheble G B | 1995 | 1EEE Transactions on Power Systems1995，10，3： | 1 |
| 4 | Weight-bearing activity during youth is a more important factor for peak bone mass than calcium intake显示文摘 | Welten D C Kemper H C Post G B | 1994 | J Bone Miner Res1994，9，7： | 1 |
| 5 | A search of the missing carbon sink:a model of terrestrial biospheric response to landuse change and atmospheric CO2显示文摘 | King A W Emanuel W R Wullschleger S D and Post W M | 1995 | Tellus1995，47，： | 1 |
| 6 | Cognitive profile of patients with newly diagnosed Par- kinson disease 显示文摘 | Muslimovie D Post B Speelman JD | 2005 | Neurology2005，65，8： | 1 |
| 7 | Molecular basis for a direct interaction between the Syk protein-tyrosine kinase and phosphoinositide 3-kinase显示文摘 | Moon K D Post C B Durden D L | 2005 | J Biol Chem2005，280，2： | 1 |
| 8 | Patterns of placental pathology in preterm prematurerupture of membranes 显示文摘 | Amstrong W J Post M D Donnelly M | 2013 | J Dev Orig Health dis2013，4，3： | 1 |
| 9 | Spectral Response of Plant Canopy with Different Soil Background显示文摘 | Huete A R Jackson R D Post D E | 1985 | Remote Sensing of Environment1985，17，1： | 1 |
| 10 | Therapeutic angiogenesis using endocardial approach to administration: techniques and results 显示文摘 | Garcia L Bairn D S Post M | 1999 | Curt Interv Cardiol Rep1999，1，3： | 1 |
| 11 | Using stable isotopes to estimate trophic position:models,methods,and assumptions显示文摘 | POST D M | 2002 | Ecology2002，83，3： | 1 |
| 12 | Immune cell function testing: an adjunct to therapeutic drug monito- ring in transplant patient management显示文摘 | Kowalski R Post D Schneider MC | 2003 | Clin Trans- plant2003，17，2： | 1 |
| 13 | Frequent inactivation of the p16 gene in human pituitary tumors by gene methylation显示文摘 | Woloschak M Yu A Post K D | 1997 | Mol Carcinog1997，19，4： | 1 |
| 14 | Determinants of disability and quality of life in mild to moderate Parkinson disease显示文摘 | Muslimovic D Post B Speelman jD | 2008 | Neurology2008，70，23： | 1 |
| 15 | Molecular diversity among marine picophytoplankton as revealed by psbA analyses 显示文摘 | Zeidner G Preston C M Delong E F Massana R Post A F Scanlan D L B6ja O | 2003 | Environ Microbio2003，，5： | 1 |
| 16 | New competition models unite ecological theory显示文摘 | Huston M A Deangelis D L Post W | 1988 | Bioscience1988，38，10： | 1 |
| 17 | Evaluation of disease status with sensitive measures of growth hormone secretion in 60 postoperative patients with acromegaly显示文摘 | Freda P U Post K D Powell J S | 1998 | J Clin Endocrin of Metabo1998，83，11： | 1 |
| 18 | Using stable isotopes to estimate trophic position: models, methods, and assumptions 显示文摘 | Post D M | 2002 | Ecology2002，83，3： | 1 |
| 19 | Cognitive profile of patients with newly diagnosed Parkinson disease显示文摘 | Muslimovic D Post B Speelman JD | 2005 | Neurology2005，65，8： | 1 |
| 20 | Cognitive decline in Parkinson's disease:aprospective longitudinal study显示文摘 | Muslimovic'D Post B Speelman JD | 2009 | J Int Neuropsychol Soc2009，15，3： | 1 |
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