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14篇 您的检索式:作者名="Polavaram"
    题名 作者 年代 出处 被引量
1Health care co- sts and mortality associated with nosocomial diarrheadue to Clostridium difficile显示文摘Kyne L Hamel MB Polavaram R 2002Clin Infect Dis2002,34,3:1
2Health care costs and mortality associated with nosocomial diarrhea due to Clostridium difficile显示文摘Kyne L Hamel MB Polavaram R 2002Clin Infect Dis2002,34,3:1
3Health care costs and mortality associated with nosocomial diarrhea due to Clostridium difficile显示文摘KYNW L HAMEL M B POLAVARAM R 2002Clin Infect Dis2002,34,:1
4Ultrafiltration in heart failure显示文摘Guglin M Polavaram L 2007Cardiol Rev2007,15,5:1
5Health care costs and mortality associated with nosocomial diarrhea due to Clostridium difficile显示文摘Kyne L Hamel MB Polavaram R 2002Clin Infect Dis2002,34,:1
6Tumor-and osteoclast-derived NRP2 in prostate cancer bone metastases显示文摘Understanding the role of neuropilin 2(NRP2)in prostate cancer cells as well as in the bone microenvironment is pivotal in the development of an effective targeted therapy for the treatment of prostate cancer bone metastasis.We observed a significant upregulation of NRP2 in prostate cancer cells metastasized to bone.Here,we report that targeting NRP2 in cancer cells can enhance taxane-based chemotherapy with a better therapeutic outcome in bone metastasis,implicating NRP2 as a promising therapeutic target.Since,osteoclasts present in the tumor microenvironment express NRP2,we have investigated the potential effect of targeting NRP2 in osteoclasts.Our results revealed NRP2 negatively regulates osteoclast differentiation and function in the presence of prostate cancer cells that promotes mixed bone lesions.Our study further delineated the molecular mechanisms by which NRP2 regulates osteoclast function.Interestingly,depletion of NRP2 in osteoclasts in vivo showed a decrease in the overall prostate tumor burden in the bone.These results therefore indicate that targeting NRP2 in prostate cancer cells as well as in the osteoclastic compartment can be beneficial in the treatment of prostate cancer bone metastasis.Navatha Shree Polavaram Samikshan Dutta Ridwan Islam Arup K.Bag Sohini Roy David Poitz Jeffrey Karnes Lorenz C.Hofbauer Manish Kohli Brian A.Costello Raffael Jimenez Surinder K.Batra Benjamin A.Teply Michael H.Muders Kaustubh Datta 2021Bone Research2021,9,2:1
7Anatomic variants and pearls-functional endoscopic sinus surgery 显示文摘Polavaram R Devaiah AK Sakai O 2004Otolaryngol Clin North Am2004,37,2:1
8Health care costs and mortality associated wtth nosocomial diarrhea due to Clostridiumdifficile显示文摘Kynw L Hamf l MB Polavaram R 2002Clin Infect Dis2002,34,3:1
9Survival effect of venous thromboembolism in patients with multiple myeloma treated with lenalidomide and high-dose dexamethasone显示文摘Zangari M Tricot G Polavaram L 0,,:1
10Healthcare costs and mortality associated with nosocomial diarrhea due to Clostridium dififcile显示文摘Kyne L Hamel MB Polavaram R 0,,03:1
11Health care costs and mortality associated with nosocomial diarrhea due to Clostridium difficile显示文摘 Hamel MB Polavaram R Kelly CP 2002Clin Infect Dis2002,34,3:1
12Health care costs and mortality associated with nosocomial diarrhea due to Clostridium diffcile显示文摘Kyne L Hamel MB Polavaram R 2002Clin Infect Dis2002,34,3:1
13Ultrafiltration in heart failure显示文摘Guglin M Polavaram L 2007Cardiol Rev2007,15,5:1
14Angiogenic growth factor axis in autophagy regulation显示文摘Stanton MJ Dutta S Polavaram NS 2013Autophagy2013,9,5:1
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