维普中文期刊产品整合服务
649篇 您的检索式:作者名="Pitt R"
    题名 作者 年代 出处 被引量
1Platelet thromboxane(11-dehydro-Thromboxane B_2) and aspirin response in patients with diabetes and coronary artery disease显示文摘Aspirin(ASA) irreversibly inhibits platelet cyclooxygenase-1(COX-1) leading to decreased thromboxane-mediated platelet activation. The effect of ASA ingestion on thromboxane generation was evaluated in patients with diabetes(DM) and cardiovascular disease. Thromboxane inhibition was assessed by measuring the urinary excretion of 11-dehydro-thromboxane B2(11dhTxB2), a stable metabolite of thromboxane A2. The mean baseline urinary 11dhTxB2 of DM was 69.6% higher than healthy controls(P = 0.024): female subjects(DM and controls) had 50.9% higher baseline 11dhTxB2 than males(P = 0.0004), while age or disease duration had no influence. Daily ASA ingestion inhibited urinary 11dhTxB2 in both DM(71.7%) and controls(75.1%, P < 0.0001). Using a pre-established cut-off of 1500 pg/mg of urinary 11dhTxB2, there were twice as many ASA poor responders(ASA 'resistant') in DM than in controls(14.8% and 8.4%, respectively). The rate of ASA poor responders in two populations of acute coronary syndrome(ACS) patients was 28.6 and 28.7%, in spite of a significant(81.6%) inhibition of urinary 11dhTxB2(P < 0.0001). Both baseline 11dhTxB2 levels and rate of poor ASA responders were significantly higher in DM and ACS compared to controls. Underlying systemic oxidative inflammation may maintain platelet function in atherosclerotic cardiovascular disease irrespective of COX-1 pathway inhibition and/or increase systemic generation of thromboxane from non-platelet sources.Luis R Lopez Kirk E Guyer Ignacio Garcia De La Torre Kelly R Pitts Eiji Matsuura Paul RJ Ames 2014World Journal of Diabetes2014,5,2:13
2Efficient Bayesian inference for Gaussian copula regression models 显示文摘Pitt M Chan D Kohn R 2006Biometrika2006,93,3:1
3A model of aerobic fungal growth in silage显示文摘Muck R E Pitt R E Leibensperger R Y 1991Grass and Forage Science1991,46,:1
4Prediction of ruminal volatile fatty acids and pH within the net carbohydrate and protein system显示文摘Pitt R E Van KesselJ S Fox D G 1996J Anita Sci1996,74,:1
5The molecular make-up of a tumour: proteomics in cancer research显示文摘Kolch W Mischak H Pitt A R 2005Clin Sci (Lond)2005,108,5:1
6Investigation of dry-weather pollurant entries into storm-drainage systems显示文摘Field R Pitt R Lalor M 1994Journal of Environmental Engineering1994,120,5:1
7Enhancement of photochemical smog by n,n'-diethylhydroxylamine in polluted ambient air显示文摘PITTS J N SMITH J P FITZ D R 1977Science1977,197,:1
8Study of Multi-site Damage of Fuselage Lap Joints显示文摘JONES R MOLENT L PITT S 1999Theoretical and Applied Fracture Mechanics1999,32,1:1
9Incentive Compensation and Organization Design显示文摘 1974Personnel Journal1974,,2:1
10Nature of the Electon Interactions in Aryl-substituted polysilanes显示文摘Pitt C G Carey R N Toren E C Jr 1972J Am Chem Soc1972,94,11:1
11Effect of losartan compared with captopril on mortality in patients with symptomatic heart failure:randomised trial-the Losartan Heart Failure Survival Study ELITE Ⅱ显示文摘Pitt B Poole-Wilson PA Segal R 2000Lancet2000,355,:1
12Corporate Objectives in Sports Sponsorship 显示文摘Abratt R Clayton B C Pitt L F 1987Oxfordshire: International Journal of Advertising1987,,6:1
13The Impact of Group-based Credit Programs on Poor Households in Bangladesh: Does the Gender of the Participants Matter?显示文摘Pitt Mark M Shahidur R Khandker 1988Journal of Political Economy1988,106,5:1
14Percutaneous translu- minal coronary angioplasty improves survival in acute my- ocardial infarction complicated by cardiogenic shock 显示文摘Lee L Bastes E R Pitt B 1988Circulation1988,78,6:1
15The efficacy of eprinomectin against induced infections of immature (fourthlarvalstage) and adult nematode parasites in cattle 显示文摘Pitt S R Langholff W K Eagleson J S 1997Veterinary Parasitol1997,73,12:1
16Hot off the press显示文摘Hill Robert A Pitt Andrew R 1999Natural Product Reports1999,16,:1
17Application of the Cornell net carbohydrate and protein model for cattle consuming forage 显示文摘Fox D G Barry M C Pitt R E 1995Journal of Animal Science1995,73,:1
18Nature of the Electon Interactions in Aryl-substituted polysilanes显示文摘Pitt C G Carey R N Toren E C Jr 1972J Am Chem Soc1972,94,11:1
19Mineral trioxide aggregate stimulates a biological response in human osteoblasts显示文摘Koh ET Torabinejad M Pitt Ford T R 1997J Biomed Mater Res1997,37,3:1
20Renal outcomes with different fixed-dose combination therapies in patients with hypertension at high risk for cardiovascular events (ACCOMPLISH): a prespecified secondary analysis of a randomised controlled trial显示文摘George L Bakris Pantelis A Sarafidis Matthew R Weir Bj?rn Dahl?f Bertram Pitt Kenneth Jamerson Eric J Velazquez Linda Staikos-Byrne Roxzana Y Kelly Victor Shi Yann-Tong Chiang Michael A Weber 2010The Lancet2010,,9721:1
返回顶部 每页显示:
共33页 首页 上一页 第1页 下一页 末页 /33 跳转

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1 渝公网安备 50019002500403号 违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费