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11篇 您的检索式:作者名="Pisera"
    题名 作者 年代 出处 被引量
1Structure and functions of the translation initiation factor eIF4E and its role in cancer development and treatment显示文摘In eukaryotic cells, protein synthesis is a complex and multi-step process that has several mechanisms to start the translation including cap-dependent and cap-independent initiation. The translation control of eukaryotic gene expression occurs principally at the initiation step. In this context, it is critical that the eukaryotic translation initiation factor eIF4E bind to the 7-methylguanosine(m7G) cap present at the 50-UTRs of most eukaryotic mRNAs. Combined with other initiation factors, eIF4E mediates the mRNA recruitment on ribosomes to start the translation. Moreover, the eIF4E nuclear bodies are involved in the export of specific mRNAs from the nucleus to the cytoplasm. In this review, we focus on the eIF4E structure and its physiological functions, and describe the role of eIF4E in cancer development and progression and the current therapeutic strategies to target eIF4E.Arianna Pisera Adele Campo Salvatore Campo 2018Journal of Genetics and Genomics2018,45,1:5
2Late Quaternary reef growth and sea level in the Maldives(Indian Ocean)显示文摘Gischler E Hudson J.H Pisera A 0,,:1
3Adenoviral vectors encoding tumor necrosis factor-alpha and FasL induce apop- tosis of normal and tumoral anterior pituitary cells 显示文摘Candolfi M Jaita G Pisera D 2006J Endocrinol2006,189,:1
4Neurokinin A inhibits oxytocin and GABA elease from the posterior pituitary by stimulating nitric oxide synthase 显示文摘Laurentiis A D Pisera D Duvilanski B 2000Brain Research Bulletin2000,53,3:1
5Effect of interleukin-6 and tumor necrosis facror-alpha on GABA release from mediobasal hypothalamus and posterior pituitary 显示文摘De Laurentiis A Pisera D Lasaga M 2000Neuroimmunomdulation2000,7,2:1
6Ureterocele associated to duplex system:an individualized approach to endoscopic incision显示文摘CALISTI A ORIOLO L PISERA A 2002Minerva Pediatr2002,54,5:1
7Ascher's syndrome: report of 2 cases显示文摘Kruk-Jeromin J Pisera P 1999Pol Merkur Lekarski1999,7,42:1
8Effect of interleukin - 6 and tumor necrosis factor - alpha on GABA release from mediobasal hypothalamus and posterior pituitary 显示文摘De LaurentiisA Pisera D Lasaga M 2000Neuroimmunomdulation2000,7,2:1
9Ascher's syndrome: report of 2 cases显示文摘Kruk-Jeromin J Pisera P 1999Pol Merkur Lekarski1999,7,42:1
10Gene therapy for pituitary tumors显示文摘Seilicovich A Pisera D Sciascia SA 2005Curt Gene Ther2005,5,6:1
11Nitric oxide inhibits hypothalamic luteinizing hormone-releasing hormone release by releasing gamma-aminobutyric acid显示文摘SEILICOVICH A DUVILANSKI B H PISERA D 1995Pro Natl Acad Sci USA1995,92,8:1
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