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74篇 您的检索式：作者名="Pion"

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	题名	作者	年代	出处	被引量
1	Remifentanil‐propofol vs. sufentanil‐propofol: optimal combinations in clinical anesthesia显示文摘	C.Lentschener A.Ghimouz P.Bonnichon C.Pépion A.Gomola Y.Ozier	2002	Acta Anaesthesiologica Scandinavica2002，，1：	2
2	Human immunodeficiency virus type-1 induces a regulatory B cell-like phenotype in vitro显示文摘Individuals infected with human immunodeficiency virus type-1(HIV-1)usually show a general dysregulation and hyper-activation of the immune system.A direct influence of HIV-1 particles on B-cell phenotypes and functions has been previously described.However,the consequences of B-cell dysregulation are still poorly understood.We evaluated the phenotypic changes in primary B cells after direct contact with HIV-1 particles in comparison with different types of stimuli.The functionality of treated B cells was challenged in co-culture experiments with autologous CD4+and CD8+T cells.We demonstrated that HIV-1 induces a phenotypic change in B cells towards a regulatory B-cell phenotype,showing a higher level of IL-10,TGF-β1,EBI3 or IL-12(p35)mRNA expression and acquiring an immunosuppressive profile.The acquisition of a Breg phenotype was confirmed by co-culture experiments where HIVtreated B cells reduced the proliferation and the TNFαproduction of CD4+or CD8+T cells.This suppressive ability of HIV-treated B cells was dependent on cell-to-cell contact between these B cells and effector cells.To our knowledge,these data provide the first evidence that HIV-1 can directly induce a regulatory B cell-like immunosuppressive phenotype,which could have the ability to impair specific immune responses.This dysregulation could constitute one of the mechanisms underlying unsuccessful efforts to develop an efficient vaccine against HIV-1.	Jacobo Lopez-Abente Adrián Prieto-Sanchez Maria-Ángeles Muñoz-Fernandez Rafael Correa-Rocha Marjorie Pion	2018	Cellular & Molecular Immunology2018，15，10：	2
3	Lentivirus - mediated RNA interference of DC - SIGN expression inhibits human immunodeficien- cy Virus transmission form dendritic cell to T cell显示文摘	Arrihi JF Pion M Wiznerowiez M	2004	J Virol2004，78，10：	1
4	Lentivirus-mediated RNA interference of DC-SIGN expression inhibits human immunodeficiency virus transmission from dendritic cells to T cells显示文摘	Arrighi JF Pion M Wiznerowicz M	2004	J Virol2004，78，10：	1
5	Langerin is a natural barrier to HIV-I transmission by Langerhans cells 显示文摘	de Witte L Nabatov A Pion M	2007	Nat Med2007，13，3：	1
6	Effects of vitamin C supplementation on plasma ascorbic acid and oxalate concentrations and meat quality in swine显示文摘	S J Pion E van Heugten M T See	2004	J Anim Sci2004，82，：	1
7	Effects of vitamin supplementation on plasma ascorbic acid and oxalate concentrationsQ' and meat quality in swine 显示文摘	PION S J Van HEUGTEN E SEE M T	2004	J Anim Sci2004，82，7：	1
8	The value of non- sport-specific characteristics for talent orientation in young male judo, karate and taekwondo athletes显示文摘	Pion J Fransen J Lenoir M	2014	Archives of Budo2014，，10：	1
9	Lentivirus-mediated RNA interference of DC-SIGN expression inhibits human immtmodefieieney virus transmission from dendritic cells to T cells显示文摘	Jean-Francois Arrighi Marjorie Pion Maciej Wiznerowicz	2004	J Viral2004，78，10：	1
10	Incidence of growth hormone deficiency in pediatric-onset Langerhans cell histiocytosis: efficacy and safety of growth hormone treatment显示文摘	Donadieu J Rolon MA Pion I	2004	J Clin Bndocrinol Metab2004，89，2：	1
11	Langerin is a natural barrier to HIV-1 transmission by Langerhans cells显示文摘	De Witte L Nabatov A Pion M	2007	Nat Med2007，13，3：	1
12	DNA-induced dimerization of poly(ADP ribose)polymerase-1 triggers its activation显示文摘	PION E ULLMANN G M AM? J C	2005	Bio-chemistry2005，44，14：	1
13	Effects of vitamin C supplementation on plasma ascorbic acid and oxalate concentrations and meat quality in swine显示文摘	Pion S J Van E See M T	2004	J Anim Sci2004，82，：	1
14	Effects of vitamin C supplementation on plasma ascorbic acid and oxalate concentrations and meat quality in swine显示文摘	Pion S J Heugten E Van See M T	2004	J Anim Sci2004，82，：	1
15	Ultrawideband coherent processing显示文摘	Cuomo K M Pion J E Mayhan J T	1999	Antennas and Propagation IEEE Transactions on1999，47，：	1
16	Myocardial failure in cats associated with low plasma taufine:a reversible cardiomyopathy显示文摘	Pion PD Kittleson MD Rogers QR	1987	Science1987，237，4816：	1
17	Repair and evaluation of a damaged truss fiver显示文摘	BEAUCHAMP J C CHAN M Y T PION R H	2006	Canadian Journal of Civil Engineering2006，11，3：	1
18	Pregnancy after uterine artery embolization for leiomyomata:the Ontario multicenter trial显示文摘	Pion G M ocarski E Bennettl J		0，，01：	1
19	Lentivirus-mediated RNA interference of DC-SIGN expression inhibits human immunodeficiency virus transmission from dendritic cells to T cells显示文摘	Arrighi JF Pion M Wiznerowicz M	2004	J Virol2004，78，10：	1
20	Langerin is a natural barrier to HIV- 1 transmission by Langerhans Cells显示文摘	de Witte L Nabatov A Pion M	2007	Nat Med2007，13，：	1

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