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| 1 | Intraoperative cell salvage with autologous transfusion in liver transplantation显示文摘Liver transplant(LT) is the primary treatment for patients with end-stage liver disease. About 25000 LTs are performed annually in the world. The potential for intraoperative bleeding is quite variable. However, massive bleeding is common and requires blood transfusion. Allogeneic blood transfusion has an immunosuppressive effect and an impact on recipient survival, in addition to the risk of transmission of viral infections and transfusion errors, among others.Techniques to prevent excessive bleeding or to use autologous blood have been proposed to minimize the negative effects of allogeneic blood transfusion.Intraoperative reinfusion of autologous blood is possible through previous selfdonation or blood collected during the operation. However, LT does not normally allow autologous transfusion by prior self-donation. Hence, using autologous blood collected intraoperatively is the most feasible option. The use of intraoperative blood salvage autotransfusion(IBSA) minimizes the perioperative use of allogeneic blood, preventing negative transfusion effects without negatively impacting other clinical outcomes. The use of IBSA in patients with cancer is still a matter of debate due to the theoretical risk of reinfusion of tumor cells. However, studies have demonstrated the safety of IBSA in several surgical procedures, including LT for hepatocellular carcinoma. Considering the literature available to date, we can state that IBSA should be routinely used in LT, both in patients with cancer and in patients with benign diseases. | Marcelo A Pinto Marcio F Chedid Leo Sekine Andre P Schmidt Rodrigo P Capra Carolina Prediger Jo?o E Prediger Tomaz JM Grezzana-Filho Cleber RP Kruel | 2019 | World Journal of Gastrointestinal Surgery2019，11，1： | 16 |
| 2 | High prevalence of vitamin A deficiency in Crohn's disease patients according to serum retinol levels and the relative dose-response test显示文摘AIM:To assess the vitamin A status of patients with Crohn's disease(CD) by evaluating serum retinol levels and the relative dose response(RDR) test(liver retinol stores).METHODS:Vitamin A nutritional status was measured by serum retinol obtained by high performance liquid chromatography and the RDR test for evaluation of the hepatic stores.Body composition was performed by densitometry by dual-energy X-ray absorptiometry.Vitamin A dietary intake was assessed from a semiquantitative food frequency questionnaire.RESULTS:This study included 38 CD patients and 33 controls.Low serum retinol concentrations were detected in 29% of CD patients vs 15% in controls(P < 0.005).The RDR test was positive in 37% of CD patients vs 12% in controls,which indicated inadequate hepatic vitamin A stores(P < 0.005).Individuals with hypovitaminosis A had lower BMI and body fat compared with those without this deficiency.There was no association between vitamin A deficiency and its dietary intake,ileal location,presence of disease activity and prior bowel resections.CONCLUSION:Patients with CD have higher prevalence of vitamin A deficiency,as assessed by two independent methods. | Márcia Soares-Mota Tianny A Silva Luanda M Gomes Marco AS Pinto Laura MC Mendon?a Maria Lúcia F Farias Tiago Nunes Andrea Ramalho Cyrla Zaltman | 2015 | World Journal of Gastroenterology2015，21，5： | 4 |
| 3 | Liver preservation prior to transplantation: Past, present, and future显示文摘Since Dr. Thomas Starzl performed the first series of successful liver transplants(LTs), important advances have been made in immunosuppression, operative techniques, and postoperative care. In 1988, Belzer's group reported the first successful LT using the University of Wisconsin preservation solution(UW).Since then, UW has replaced EuroCollins solution and allowed prolonged and safer preservation of liver, kidney, and pancreas allografts, thus contributing to the improvement of transplant outcomes. Although UW is still considered the standard of care in the United States and in several countries worldwide, a recent meta-analysis revealed similar LT outcomes among UW, Celsior solution, and the Institut Georges Lopez-1 preservation solution, which were slightly superior to those obtained with histidine-tryptophan-ketoglutarate preservation solution.Dynamic preservation has been recently developed, and liver allografts are preserved mainly through the following methods: hypothermic machine perfusion, normothermic machine perfusion, and subnormothermic machine perfusion. Their use has the potential advantage of improving clinical results in LT involving extended criteria donor allografts. Although associated with increased costs, techniques employing machine perfusion of liver allografts have been considered clinically feasible. This editorial focuses on recent advances and future perspectives in liver allograft preservation. | Marcio F Chedid Marcelo A Pinto Jose Felipe G Juchem Tomaz J M Grezzana-Filho Cleber R P Kruel | 2019 | World Journal of Gastrointestinal Surgery2019，11，3： | 4 |
| 4 | Organic Light Emitting Diodes with Lithium Contained Alq3 as Electron Injection Layer显示文摘lNovel lithium doped tris 8 hydroxylquinoline aluminium(Alq3:Li) layer is deposited between emission layer and electron injection aluminium electrode as an electron injection assistant layer in different organic light emitting diodes(OLED) to lower the electron injection barrier. In these devices, Alq3 is used as emission layer, and a bilayer film of N,N bis (1 naphhyl) N,N diphenyl 1,1 biphenyle 4,4' diamine(NPB) and 4,4,4' tris(3 methyl phenylphenylamino) triphenylamine( m MTDATA) used as hole transport layer(HTL). The electroluminescent performance of devices with different thicknesses of Alq3∶Li shows that the insertion of the lithium doped Alq3 layer can reduce the turn on voltage by at least 2 volts, and the stability of devices with this lithium doped Alq3 layer is improved too. It can also change the efficiency of devices. Compared with an ultra thin lithium fluoride(LiF) layer, Alq3∶Li sheet gives similar effects but higher efficiency and can be much thicker and hence it is easier to control the deposition. | Zugang Liu 1,* and J. L. Pinto 21. Department of Materials, University of Oxford, Parks Road, Oxford OX1 3PF, UK 2. Departamento de Física, Universidade de Aveiro, 3810 194 Aveiro, Portuga | 2002 | Chemical Research in Chinese Universities2002，18，2： | 2 |
| 5 | Phase II study of cetuximab in combination with FOLFIRI in patients with untreated advanced gastric or gastroesophageal junction adenocarcinoma ( FOLCETUX study) 显示文摘 | PINTO C DI FABIO F SIENA S | 2007 | Ann Oncol2007，18，3： | 1 |
| 6 | Phase Ⅱ study of cetuximab plus FOLFIRI as first-line treatment in patients with unresectable/metastatic gastric or gastroesophageal junction (GEJ) adenocarcinoma (FOLCETUX study):preliminary results显示文摘 | Pinto C Di Fabio F Siena S | 2006 | J Clin Oncol2006，24，18： | 1 |
| 7 | Small bowe volvulus combined radiological findings显示文摘 | Lassandro F Giovine S Pinto A | 2001 | Radiol Med (Torino)2001，102，12： | 1 |
| 8 | Simulation of Agroforestry Systems With Sugarcane in Piracicaba,Brazil显示文摘 | PINTO L F G BERNARDES M S NOORDWIJK M V | 2005 | Agricultural Systems2005，86，3： | 1 |
| 9 | Sep Sci Technol 显示文摘 | Arafat H A Ahnert F Pinto N G | 2004 | 39(1): 43-622004，39，1： | 1 |
| 10 | The study of reactions influencing the biomass steam gasification gasification process 显示文摘 | Franco C Pinto F Gulyurtlu I | 2003 | Fuel2003，，7： | 1 |
| 11 | Planning and scheduling models for refinery operations 显示文摘 | Pinto J M Joly M Moro L F L | 2000 | Computers & Chemical Engineering2000，24，910： | 1 |
| 12 | Long-term resuits of percutaneous ethanol injection therapy for hcpatocellular carcinoma in cirrhosis: a European experience 显示文摘 | Lencioni R Pinto F Armillotta N | 1997 | Eur Radiol1997，7，： | 1 |
| 13 | The chemistry of isatins:a review from 1975 to 1999显示文摘 | Silva J F M Garden S J Pinto A C | 2001 | Braz Chem Soc2001，12，： | 1 |
| 14 | Phase Ⅱ study of cetuximab in combination with FOLFIRI in patients with untreated advanced gastric or gastroesophageal junction adenocarcinoma (FOLCETUX study)显示文摘 | Pinto C Fabio F D Siena S | 2007 | Annals of Oncology2007，18，3： | 1 |
| 15 | The antioxidant systems vis-a-vis reactive oxygen species during plant-pathogen inter action显示文摘 | De Gara L de Pinto M C Tommasi F | 2003 | Plant Physiology and Biochemistry2003，41，10： | 1 |
| 16 | Regional graduation of Ltype calcium currents in the feline heart with a healed myocardial infarct显示文摘 | Pinto JMB Yuan F Wasserlauf BJ | 1997 | J Cardiovasc Electrophysiol1997，8，： | 1 |
| 17 | Capecitabine plus oxaliplatin(xelox)versus protracted5-fluorouracil venous infusion plus oxaliplatin(pvifox)as first-line treatment in advanced colorectal cancer:A GOAM phase II randomised study(FOCA trial)显示文摘 | Martonia AA Pinto C Di Fabio F | 2006 | Eur J Cancer2006，42，18： | 1 |
| 18 | Subrrigationreduces water use,nitrogen loss and moss growth in a containernursery显示文摘 | Dumroese R K Pinto J R Jacobs D F | 2006 | Native plants2006，7，3： | 1 |
| 19 | Trastuzumabfor patients with HER2 positive breast cancer: delivery,duration and combination therapies显示文摘 | Pinto AC Ades F de Azambuja E ef af | 2013 | Breast2013，，2： | 1 |
| 20 | Origins andfunctional impact of copy number variation in the hu-man genome显示文摘 | Conrad D F Pinto D Redon R | 2010 | NaZwr^2010，464，： | 1 |
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