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1Low serum neutralizing anti-SARS-CoV-2 S antibody levels in mildly affected COVID-19 convalescent patients revealed by two different detection methods显示文摘Neutralizing antibodies targeting the receptor-binding domain(RBD)of the SARS-CoV-2 spike(S)block severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)entry into cells via surface-expressed angiotensin-converting enzyme 2(ACE2).We used a surrogate virus neutralization test(sVNT)and SARS-CoV-2 S protein-pseudotyped vesicular stomatitis virus(VSV)vector-based neutralization assay(pVNT)to assess the degree to which serum antibodies from coronavirus disease 2019(COVID-19)convalescent patients interfere with the binding of SARS-CoV-2 S to ACE2.Both tests revealed neutralizing anti-SARS-CoV-2 S antibodies in the sera of ~90% of mildly and 100% of severely affected COVID-19 convalescent patients.Importantly,sVNT and pVNT results correlated strongly with each other and to the levels of anti-SARS-CoV-2 S1 IgG and IgA antibodies.Moreover,levels of neutralizing antibodies correlated with the duration and severity of clinical symptoms but not with patient age.Compared to pVNT,sVNT is less sophisticated and does not require any biosafety labs.Since this assay is also much faster and cheaper,sVNT will not only be important for evaluating the prevalence of neutralizing antibodies in a population but also for identifying promising plasma donors for successful passive antibody therapy.Berislav Bosnjak Saskia Catherina Stein Stefanie Willenzon Anne Katrin Cordes Wolfram Puppe Gunter Bernhardt Inga Ravens Christiane Ritter Christian R.Schultze-Florey Nina Godecke Jorg Martens Hannah Kleine-Weber Markus Hoffmann Anne Cossmann Mustafa Yilmaz Isabelle Pink Marius M.Hoeper Georg M.N.Behrens Stefan Pohlm ann Rainer Blasczyk Thomas F.Schulz Reinhold Forster 2021Cellular & Molecular Immunology2021,18,4:2
2塞尚与黄宾虹:中西现代主义绘画的会通之路显示文摘20世纪初,英国著名艺术史家、批评家和美学家罗杰·弗莱在阐明其形式主义一现代主义理论时,援用了大量东方艺术思想资源,特别是中国的美学资源。弗莱发现了中国书法和绘画的魅力:对于绘画质地、笔触、书写与线条在艺术表达中的作用。而这些恰恰都是经过现代主义理论的阐发后才被凸现出来的艺术要素。他很自然地抓住东方资源,来为他激赏的西方现代派绘画艺术辩护。什么是书法?弗莱下过一个简明易懂的定义(当然比中国传统中的书法概念毛糙、简单得多):当这种线条想要达到的目标是在绝对确信的状态下作出的时候,我们称这样的线条为书法。沈语冰 Katy Pinke 2016艺术界2016,0,5:2
3Prevention ofepidural scarring after microdiscectomy : a randomizedclinical trial comparing gel and expanded polytetrafluoroethylenemembrane 显示文摘Ivanic GM Pink PT Schneider F 2006Eur Spine J2006,15,9:1
4Angiotensin Ⅱ directly increases transforming growth factor beta1 and osteopontin and indirectly affects collagen mRNA expression in the human heart显示文摘Kupfahl C Pink D Friedrich K 2000Cardiovasc Res2000,46,3:1
5Biology of the chicken MHC(B complex)显示文摘Plachy J Pink J Hala K 1992Critical Reviews in Immunolog1992,12,12:1
6NAD(P)H:Quinone oxidoreductase activity is the principal determinant of β-lapachone cytotoxicity显示文摘Pink JJ Planchon SM Tagliarino C 2000J Biol Chem2000,275,8:1
7Pink's motivation principles 显示文摘PINK D 2011Credit Union Magazine2011,,8:1
8Benefits of power electronic interfaces for distributed energy systems显示文摘KROPOSKI B PINK C DEBLASIO R 2010IEEE Transactions on Power Electronics2010,19,6:1
9Relative contribution of acromioclavicular joint capsule and coracoclavicular ligaments to acromioclavicular stability显示文摘Dawson PA Adamson GJ Pink MM 2009J Shoulder Elbow Surg2009,18,2:1
10Primary lymp-homa of the stomach:three-year results of a prospective multicenter study显示文摘Koch P Grothaus pinke B Hiddenmann W 1997Ann Oncol1997,8,1:1
11Marfan syndrome Long-term survivsl and Complications after arotic aneurysm repair显示文摘Pink bohner R Johnston D Crawford ES 1995Circulation1995,91,5:1
12The molecular analysis of leaf senescence-A genomics approach显示文摘BUCHANAN-WOLLASTON V EARL S HARRISON E MATHAS E NAVABPOUR S PAGE T PINK D 2003Plant Biotechnology Journal2003,1,:1
13Comparative electromyographic analysis of shoulder muscles during planar motions:anterior glenohumeral instability versus normal 显示文摘McMahon PJ Jobe FW Pink MM 1996J Shoulder Elbow Surg1996,5,:1
14Light conditions influence specific defence respanses in incompatible plant-pathosen interactions:uncoupling systemic resistance from salicylic acid and PR-1 accumulation显示文摘Zeier J Pink B Mueller M J 2004Planta2004,219,4:1
15Modification of a laser-based flow cytometer for high resolution DNA analysis of mammalian spermatozoa 显示文摘Johnson LA Pink D 1986Cytometry1986,7,:1
16The distribution of stress-drop sizes in serrated flow of an aluminum alloy and a mild steel显示文摘Pink E Kumar S Tian B 2000Mater Sci Eng A2000,280,:1
17Diffusion-weightedmagnetic resonance imaging allows monitoring of antican-cer treatment effects in patients with soft-tissue sarcomas显示文摘Dudeck 0 Zeile M Pink D 2008J Magn Reson Imaging2008,27,5:1
18Saliva as a diagnostic medium显示文摘Pink R Simek J Vondrakova J 0,,02:1
19Evaluation of a core collection of Brassica oleracea accessions for resistance to Brevico- ryne brassica,the cabbage aphid显示文摘Ellis P R Pink D A Phelps K 1998Euphytica1998,103,2:1
20Angiotensin Ⅱ directly increases transforming growth factor betal and osteopontin and indirectly affects collagen mRNA expression in the human heart显示文摘 Pink D Friedrich K 2000Cardiovasc Res2000,46,3:1
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