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| 1 | Simulation experiments on secondary thermal stress of biodegraded bituminous sandstones显示文摘Secondary variation of reservoir is a hot problem in petroleum geochemistry field. Several kinds of secondary variations have taken place after the formation of bituminous sandstones in the Tarim Basin including biodegra-dation, washing, dissipation and secondary thermal stress. Biodegraded bituminous sandstones were used in the experiment. Pyrolysis experiment has been performed in a closed system, simulating secondary thermal stress with continual burial of Silurian bituminous sandstones which may cause the changes in molecular compositions, carbon isotope and physical properties of bituminous sandstones. The results are as follows: (i) Gases are mainly product during the experiment and carbon isotope of gas is lighter. (ii) Yield of C6+ hydrocarbon is relative smaller, and yielded oil is mainly light oil. (iii) Chromatogram character of biodegraded oil-sand is similar to that of saturated hydrocarbon in extracts from present-day bituminous sandstones, (iv) Porosity of bituminous sandstones gradually | GONG Se PENG Ping’an LU Yuhong XIAO Zhongyao JIA Wanglu WANG Zhenqi YU Chiling LIU Dehan LU Jialan LIU Jinzhong | 2004 | Chinese Science Bulletin2004，49，S1： | 1 |
| 2 | Petroleum charge history in the Lunnan Low Uplift, Tarim Basin, China – Evidence from oil-bearing fluid inclusions显示文摘 | Se Gong Simon C. George Herbert Volk Keyu Liu Ping’an Peng | 2007 | Organic Geochemistry2007，，8： | 1 |
| 3 | Effects of estrogen on basal forebrain cholinergic neurons and spatial learning 显示文摘 | Ping SE Trieu J Wlodek ME | 2005 | J Neurosci Res2005，56，： | 1 |
| 4 | Stable Pd/V2O5 optical H2sensor显示文摘 | Liu Ping Lee Se Hee Hyeonsik M | 2002 | Journal of the Electrochemical Society2002，149，3： | 1 |
| 5 | Estrogen treatment suppresses forebrain p75 neurotrophin receptor expression in aged,noncycling female rats显示文摘 | Ping SE Greferath U Barrett GL | 2002 | J Neurosci Res2002，69，1： | 1 |
| 6 | The treatment of irresectable liver tumors by percutaneous targeted Ar2He Cry- oablati0n显示文摘 | Se mingWang Ji ren Zhang Qiu ping Ren | 2000 | International Journal of Modem Cancer Therapy2000，3，1： | 1 |
| 7 | Effects of estrogen on basal forebrain cholinergie neurons and spatial learning显示文摘 | Ping SE Trieu J Wlodek ME | 2008 | J Neuroscia Res2008，86，7： | 1 |
| 8 | Electrochromic and optical properties of mesoporous tungstenoxide films 显示文摘 | Ozkan E Se - Hee L Ping L | 2002 | Solid State Ionies2002，149，： | 1 |
| 9 | Development of a potential PET probe for HDAC6 imaging in Alzheimer's disease显示文摘Although the epigenetic regulatory protein histone deacetylase 6(HDAC6)has been recently implicated in the etiology of Alzheimer’s disease(AD),little is known about the role of HDAC6 in the etiopathogenesis of AD and whether HDAC6 can be a potential therapeutic target for AD.Here,we performed positron emission tomography(PET)imaging in combination with histopathological analysis to better understand the underlying pathomechanisms of HDAC6 in AD.We first developed[^(18)F]PB118 which was demonstrated as a valid HDAC6 radioligand with excellent brain penetration and high specificity to HDAC6.PET studies of[^(18)F]PB118 in 5xFAD mice showed significantly increased radioactivity in the brain compared to WT animals,with more pronounced changes identified in the cortex and hippocampus.The translatability of this radiotracer for AD in a potential human use was supported by additional studies,including similar uptake profiles in non-human primates,an increase of HDAC6 in ADrelated human postmortem hippocampal tissues by Western blotting protein analysis,and our ex vivo histopathological analysis of HDAC6 in postmortem brain tissues of our animals.Collectively,our findings show that HDAC6 may lead to AD by mechanisms that tend to affect brain regions particularly susceptible to AD through an association with amyloid pathology. | Ping Bai Prasenjit Mondal Frederick A.Bagdasarian Nisha Rani Yan Liu Ashley Gomm Darcy R.Tocci Se Hoon Choi Hsiao-Ying Wey Rudolph E.Tanzi Can Zhang Changning Wang | 2022 | Acta Pharmaceutica Sinica B2022，12，10： | 0 |
| 10 | Occupational Exposure to Indium of Indium Smelter Workers显示文摘Case reports of indium-related lung disease in workers have raised public concern to the human toxicity of indium(In)and its compounds.However,studies evaluating the exposure or health of workers in In smelting plants are rare.Therefore,in this study,we focused on four In smelting plants,with the main objective of characterizing In | DING Chun Guang WANG Huan Qiang SONG Han Bo LI Zhi Hui LI Xiao Ping YE Shao Se ZHANG Fu Gang CUI Shi Wei YAN Hui Fang LI Tao | 2016 | Biomedical and Environmental Sciences2016，29，5： | 0 |
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