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您的检索式：作者名="Ping Caipeng"
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| 1 | Application of synthetic biology in bladder cancer显示文摘Bladder cancer(BC)is the most common malignant tumor of the genitourinary system.The age of individuals diagnosed with BC tends to decrease in recent years.A variety of standard therapeutic options are available for the clinical management of BC,but limitations exist.It is difficult to surgically eliminate small lesions,while radiation and chemotherapy damage normal tissues,leading to severe side effects.Therefore,new approaches are required to improve the efficacy and specificity of BC treatment.Synthetic biology is a field emerging in the last decade that refers to biological elements,devices,and materials that are artificially synthesized according to users’needs.In this review,we discuss how to utilize genetic elements to regulate BC-related gene expression periodically and quantitatively to inhibit the initiation and progression of BC.In addition,the design and construction of gene circuits to distinguish cancer cells from normal cells to kill the former but spare the latter are elaborated.Then,we introduce the development of genetically modified T cells for targeted attacks on BC.Finally,synthetic nanomaterials specializing in detecting and killing BC cells are detailed.This review aims to describe the innovative details of the clinical diagnosis and treatment of BC from the perspective of synthetic biology. | Mengting Ding Jiaxing Lin Caipeng Qin Ping Wei Jiahe Tian Tianxin Lin Tao Xu | 2022 | Chinese Medical Journal2022，135，18： | 0 |
| 2 | Analysis on Tectonic Movement of the Longmenshan Fault Zone before the Wenchuan M_S 8. 0 Great Earthquake显示文摘On the basis of elastic rebound theory,using the horizontal velocity field of the Chinese mainland calculated from GPS data during three observation periods from 1999 to 2007,the velocity components that are parallel and plumb to the fault zone are calculated respectively for different periods,and then relative ground movements of two sides of the fault zone are analyzed with power function fitting and graphics. The results show that the relative ground movement shows right-lateral shear deformation before the Wenchuan MS8. 0 earthquake,and at the same time the movement was hindered by the Longmenshan fault zone. Thus,this result has positive significance for distinguishing the elastic strain energy accumulation and deformation anomaly in an earthquake preparation process,and for conducting further research on earthquake prediction. | Ping Jianjun Jiang Zaisen Feng Xiangdong Ping Caipeng Shan Lianjun Wang Xia | 2014 | Earthquake Research in China2014，28，3： | 0 |
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