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10篇 您的检索式:作者名="Pimentel AM"
    题名 作者 年代 出处 被引量
1Pertussis may be the cause of prolonged cough in adolescents and adults in the interepidemic period显示文摘Pimentel AM Baptista PN Ximenes RA 2015Braz J Infect Dis2015,19,1:1
2Human granu-losa cells : insulin and insulin - like growth factor - 1 receptors and aromatase expression modulation by metformin显示文摘Fuhrmeister IP Branchini G Pimentel AM 2014Gynecol Obstet Invest2014,77,3:1
3L-arginine - nitric oxide pathway and oxidative stress in plasma and platelets of patients with pre - eclampsia显示文摘Pimentel AM Pereira NR Costa CA 2013Hypertens Res2013,36,9:1
4L-arginine-nitric oxide pathway and oxidative stress in plasma and platelets of patients with pre-eclampsia显示文摘Pimentel AM Pereira NR Costa CA 2013Hypertens Res2013,36,9:1
5High numbers of human skin cancers express MMP2 and several integrin genes显示文摘Orimoto AM Neto CF Pimentel ER 2008J C utan Pathol2008,35,3:1
6Unusual penetrating orbit injury 显示文摘Bourguignon Filho AM Puppin AA Pimentel DP 2006Int J Oral Maxillofac Surg2006,35,1:1
7Active tuberculosis in inflammatory bowel disease patients under treatment from an endemic area in Latin America显示文摘BACKGROUND There has been an increase in cases of inflammatory bowel disease(IBD)in recent years.There is also greater access and availability of immunosuppressive and biological agents,which increase the risk of opportunistic infection despite improving the quality of life and promoting mucosal healing.Tuberculosis(TB)remains a public health problem,and it has a high incidence in several countries.Therefore,knowledge of the risk of developing TB in patients with IBD is important.AIM To evaluate the risk of active TB in patients with IBD under treatment from an endemic area in Latin America.METHODS A standard questionnaire included demographic variables,clinical aspects of IBD disease,history of active TB during treatment,active TB characteristics and evolution,initial screening and results and time from the start of anti-tumor necrosis factor alpha(TNFα)to TB development.RESULTS Azathioprine,anti-TNFα and the combination of these two drugs were associated with a higher risk of active TB incidence.The TNFα blockers increased the relative risk of developing active TB compared to other treatments.All four multivariable models showed that the use of TNFα blockers alone or in combination with azathioprine was an important risk factor for the incidence of active TB.After adjustment for sex,age,type of IBD and latent TB,anti-TNFα with azathioprine increased the relative risk to 17.8 times more than conventional treatment.Late TB,which was diagnosed 3 mo after the start of anti-TNFα,was the most frequent.CONCLUSION Treatment with anti-TNFα increased the risk of active TB in IBD patients from an endemic area in Latin America.This risk was increased when anti-TNFα was combined with azathioprine.The time from the beginning of the treatment to the active TB diagnosis suggests a new TB infection.Flora Maria Lorenzo Fortes Ney Boa Sorte Victor D Mariano Laila D Andrade Fernanda A Oliveira Monique CA Santos Claudia Ivanilda N dos Santos Catharina A Passos Mila P Pacheco Valdiana C Surlo Neogelia P de Almeida Jaciane AM Fontes Andrea M Pimentel Raquel Rocha Genoile Oliveira Santana 2020World Journal of Gastroenterology2020,26,44:1
8Pertussis may be the cause of prolonged cough in adolescents and adults in the interepidemic period 显示文摘Pimentel AM Baptista PN Ximenes RA 2015Braz J Infect Dis2015,19,1:1
9The role of NO-cGMP pathway and potassium channels on the relaxation induced by clonidine in the rat mesenteric arterial bed 显示文摘Pimentel AM Costa CA Carvalho LC 2007Vasc Phannacol2007,46,5:1
10High numbers of human skin cancers express MMP-2 and several integrin genes 显示文摘Orimoto AM Neto CF Pimentel ER 2008Cutan Patho2008,35,3:1
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