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| 1 | Atrial fibrillation in patients with gastroesophageal reflux disease: A comprehensive review显示文摘AIM:To analyze the potential relationship between gastroesophageal reflux disease(GERD)and the development of atrial fibrillation(AF).METHODS:Using the key words'atrial fibrillation and gastroesophageal reflux','atrial fibrillation and esophagitis,peptic','atrial fibrillation and hernia,hiatal'the PubMed,EMBASE,Cochrane Library,OVIDSP,WILEY databases were screened for relevant publications on GERD and AF in adults between January 1972-December 2013.Studies written in languages other than English or French,studies not performed in humans,reviews,case reports,abstracts,conference presentations,letters to the editor,editorials,comments and opinions were not taken into consideration.Articles treating the subject of radiofrequency ablation of AF and the consecutive development of GERD were also excluded.RESULTS:Two thousand one hundred sixty-one titles were found of which 8 articles met the inclusion criteria.The presence of AF in patients with GERD was reported to be between 0.62%-14%,higher compared to those without GERD.Epidemiological data provided by these observational studies showed that patients with GERD,especially those with more severe GERD-related symptoms,had an increased risk of developing AF compared with those without GERD,but a causal relationship between GERD and AF could not be established based on these studies.The mechanisms of AF as a consequence of GERD remain largely unknown,with inflammation and vagal stimulation playing a possible role in the development of these disorders.Treatment with proton pomp inhibitors may improve symptoms related to AF and facilitate conversion to sinus rhythm.CONCLUSION:Although links between AF and GERD exist,large randomized clinical studies are required for a better understanding of the relationship between these two entities. | Crina Roman Stanislas Bruley des Varannes Lucian Muresan Alina Picos Dan L Dumitrascu | 2014 | World Journal of Gastroenterology2014，20，28： | 16 |
| 2 | m^6A-epitranscriptome modulates memory strength显示文摘Memory traces are modified during several hours following learning, to produce behaviorally adaptive long-term memories. In a recent paper published in Cell Research, Zhang et al. provide evidence that N 6 -methyladenosine modification of mRNAs augments the strength of weak memories. | Sebastian Krüttner Pico Caroni | 2019 | Cell Research2019，29，1： | 3 |
| 3 | Comparison of solid-phase microextraction and stir bar sorptive extraction for determining six organophosphorus insecticides in honey by liquid chromatography-mass spectrometry显示文摘 | BLASCO C FERNANDEZ M PICO Y | 2004 | Journal of Chromatography A2004，1030，12： | 1 |
| 4 | Genetic diversity of some accessions of Cucurbita maxima from Spain using RAPD and SBAP markers 显示文摘 | Ferriol M Pico B Nuez F | 2003 | GRCE2003，50，3： | 1 |
| 5 | Determination of abamectin in citrus fruits by liquid chromatography-electrospray ionization mass spectrometry 显示文摘 | Valenzuela A I Redondo M J Pico Y | 2000 | Journal of Chromatography A2000，831，1： | 1 |
| 6 | Intracranial arterial dolichoectasia and its relation with atherosclerosis and stroke subtype显示文摘 | Pico F Labreuche J Touboul PJ | 2003 | Neurology2003，61，： | 1 |
| 7 | Association of small vessel disease with dilatative arteriopath of the brain:neuropathologic evidence显示文摘 | Pico F Labreuche J Sei Ihean D | 2007 | Stroke2007，38，9： | 1 |
| 8 | Determination of organochlorine pesticide residues in honey from the central zone of Portugal and the Valencian community of Spain 显示文摘 | Blasco C Lino CM Pico Y Pena A Font G Silveira M I N | 2004 | Journal of Chromatography A2004，1049，12： | 1 |
| 9 | Genetic variability and relationship of closely related Spanish traditional cultivars of tomato as detected by SRAP and SSR markers 显示文摘 | Ruiz J J Garcia - Martinez S Pico B | 2005 | J Am Soc Horticult Sci2005，130，1： | 1 |
| 10 | Genetic diversity of a germplasm collection of Cucurbita pepo using SRAP and AFLP markers显示文摘 | Ferrio M Pico B Nuez F | 2003 | Theoretical and Applied Genetics2003，107，： | 1 |
| 11 | Liquid chromatography/ atmospheric pressure chemical ionization-mass spectrometric analysis of benzoylurea insecticides in citrus fruits显示文摘 | A I Valenzuela Y Pico G Font | 2000 | Rapid Communications in Mass Spectrometry2000，14，： | 1 |
| 12 | Food safety and functional foods in the European Union:Obesity as a paradigmatic example for novel food development显示文摘 | PALOU A PICO C BONET M L | 2004 | Nutrition Reviews2004，62，7： | 1 |
| 13 | Genetic diversity of a germplasm collection of Cucurbita pepo using SRAP and AFLP markers显示文摘 | Ferriol M Pico B Nuez F | 2003 | Theoretical and Applied Genetics2003，107，： | 1 |
| 14 | Genetic diversity of a germplasm collection of Cucurbita pepo using SRAP and AFLP markers显示文摘 | Ferriol M Pico B Nuez F | 2003 | Heor Appl Genet2003，107，： | 1 |
| 15 | Secretory granules of endocrine and chief cells of human stomach mucosa contain leptin显示文摘 | CINTI S MATTEIS R D PICO C | 2000 | Int J Obes Relat Metab Disord2000，24，： | 1 |
| 16 | Genetic diversity of some cultivars of Cucurbita maxima from Spain using RAPD and SRAP marker 显示文摘 | Ferriol M Pico B Nuez F | 2003 | Genetic Resources and Crop Evolution2003，50，3： | 1 |
| 17 | Sex-differential expression of metabolism-related genes in response to a high-fat diet 显示文摘 | PRIEGO T SANCHEZ J PICO C | 2008 | Obesity (Silver Spring)2008，16，4： | 1 |
| 18 | Analytical strategies to determine quinolone residues in food and the environ- ment 显示文摘 | ANDREU V BLASCO C PICO Y | 2007 | Trends of Analytical Chemistry2007，26，6： | 1 |
| 19 | Association of small-vessel disease with dilatative arteriopathy of the brain:neuropathologic evidence显示文摘 | Pico F Labreuche J Seilhean D | 2007 | Stroke2007，38，4： | 1 |
| 20 | Determination of pesticides and their degradation products in soil: critical review and comparison of methods 显示文摘 | Andreu V Pico Y | 2004 | Trends in Analytical Chemistry2004，23，1011： | 1 |
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