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| 1 | Kinetics of phenol and m-cresol biodegradation by an indigenous mixed microbial culture isolated from a sewage treatment plant显示文摘An acclimatized mixed microbial culture,predominantly Pseudomonas sp.,was enriched from a sewage treatment plant,and its potential to simultaneously degrade mixtures of phenol and m-cresol was investigated during its growth in batch shake flasks.A 22 full factorial design with the two substrates at two different levels and different initial concentration ranges(low and high),was employed to carry out the biodegradation experiments.The substrates phenol and m-cresol were completely utilized within 21 h when present at low concentrations of 100 mg/L for each,and at high concentration of 600 mg/L for each,a maximum time of 187 h was observed for their removal.The biodegradation results also showed that the presence of phenol in low concentration range(100–300 mg/L) did not inhibit m-cresol biodegradation.Whereas the presence of m-cresol inhibited phenol biodegradation by the culture.Moreover, irrespective of the concentrations used,phenol was degraded preferentially and earlier than m-cresol.A sum kinetics model was used to describe the variation in the substrate specific degradation rates,which gave a high coeffcient of determination value(R2>0.98)at the low concentration range of the substrates.From the estimated interaction parameter values obtained from this model,the inhibitory effect of phenol on m-cresol degradation by the culture was found to be more pronounced compared to that of m-cresol on phenol.This study showed a good potential of the indigenous mixed culture in degrading mixed substrate of phenolics. | Pichiah Saravanan Kannan Pakshirajan Prabirkumar Saha | 2008 | Journal of Environmental Sciences2008，20，12： | 7 |
| 2 | Batch growth kinetics of an indigenous mixed microbial culture utilizing m-cresol asthesolecarbonsource显示文摘 | Pichiah Saravanan Pakshirajan K Prabirkumar Saha | 2009 | JournalofHazardousMaterials2009，162，： | 1 |
| 3 | Synergetic effect of conductive polymer poly(3,4-ethylenedioxythiophene) with different structural configuration of anode for microbial fuel cell application 显示文摘 | KANG YL IBRAHIM S PICHIAH S | 2015 | Bioresource Technology2015，189，： | 1 |
| 4 | Wounddressingmaterials with antibacterial activity from electrospunpolyurethane-dextran nanofiber mats containing ciprofloxacinHCl显示文摘 | Unnithan A R Barakat N A Pichiah P B | 2012 | Carbohydr Polym2012，90，4： | 1 |
| 5 | Ethanolic extract of seabuckthorn ( Hippophae rhamnoides L ) prevents high-fat diet–induced obesity in mice through down-regulation of adipogenic and lipogenic gene expression显示文摘 | P.B. Tirupathi Pichiah Hye-Jung Moon Jeong-Eun Park Yeon-Jeong Moon Youn-Soo Cha | 2012 | Nutrition Research2012，，11： | 1 |
| 6 | Doxorubicin treatment inhibits PPARγand may induce lipotoxicity by mimicking a type 2 diabetes-like condition in rodent models显示文摘 | Arunachalam S Tirupathi Pichiah PB Achiraman S | 2013 | FEBS Lett2013，587，2： | 1 |
| 7 | Growth kinetic of an indigenous mixed microbial consortium dur- ing phenol degradation in a batch reactor 显示文摘 | Pichiah Saravanan Pakshirajan K Prabirkumar Saha | 2005 | Bioresource Technology2005，99，： | 1 |
| 8 | Adriamycin-induced cardiomyopathy can serve as a model for diabetic cardiomyopathy ——a hypothesis显示文摘Diabetic cardiomyopathy is one of the life threatening complications of diabetes. A number of animal models are being used for studying diabetic cardiomyopathy. In laboratory animal models, induction of cardiomyopathy happens in two stages: first being the induction of diabetic condition and the second being the induction of cardiomyopathy by prolonging diabetic condition. It takes a longer time to develop diabetes with the limited success rate for development of cardiomyopathy. Adriamycin is an effective anticancer drug limited by its major side-effect cardiomyopathy. A number of features of Adriamycin treatment mimics diabetes. We postulate that Adriamycin-induced cardiomyopathy might be used as a model system to study diabetic cardiomyopathy in rodents since a number of features of both the cardiomyopathies overlap. Left ventricular hypertrophy, systolic and diastolic dysfunction, myofibrillar loss, and fibrosis are hallmarks of both of the cardiomyopathies. At the molecular level, calcium signaling, endoplasmic reticulum stress, advance glycation endproduct activation, mitochondrial dysfunction,inflammation, lipotoxicity and oxidative stress are similar in both the cardiomyopathies.The signature profile of both the cardiomyopathies shares commonalities. In conclusion,we suggest that Adriamycin induced cardiomyopathic animal model can be used for studying diabetic cardiomyopathy and would save time for researchers working on cardiomyopathy developed in rodent using the traditional method. | Kaviyarasi Renu V.G.Abilash P.B.Tirupathi Pichiah Thabassum Akthar Syeda Sankarganesh Arunachalam | 2017 | Asian Pacific Journal of Tropical Biomedicine2017，7，11： | 0 |
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