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| 1 | Immunocytochemieal localization of ZP3 in primordial follicles of rabbit, marmoset, rhesus monkey and human ovaries using antibodies against human ZP3 显示文摘 | Grootenhuis A J Philipsen HL | 1996 | J Reprod Fertil Suppl1996，50，： | 1 |
| 2 | Localization and expression pattern of cytoglobin in carbon tetraehloride - induced liver fibrosis 显示文摘 | Man KN Philipsen S Tan - Un KC | 2008 | Toxicol Lett2008，183，13： | 1 |
| 3 | Increased delta power and discrepancies in objective and subjective sleep measurements in borderline personality disorder显示文摘 | Philipsen A Feige B A1-Shajlawi A | 2005 | J Psychiatr Res2005，39，5： | 1 |
| 4 | A tale of three fingers: the family of mammalian Sp/XKLF transcription factors显示文摘 | PHILIPSEN S SUSKE G | 1999 | Nucleic Acids Res1999，27，15： | 1 |
| 5 | Studies on the decline of bovine virus diarrhea virus (BVDV) maternal antibodies and detectability of BVDV in persistently infected calves 显示文摘 | Palfi V Houe H Philipsen J | 1993 | Acta Vet Scand1993，，34： | 1 |
| 6 | Peripheral ameloblastoma: biological profile based on 160 cases from the literature显示文摘 | Philipsen HP Reichart PA Nikai H | 2001 | Oral Oncol2001，37，1： | 1 |
| 7 | 小鼠转基因Apoptin的持续表达对淋巴细胞发育和增殖的无干扰性(英文)显示文摘目的病毒来源的凋亡蛋白Apoptin诱导不同类型肿瘤细胞的凋亡而对正常细胞无损伤。通常,机体系统治疗往往因其对快速分裂细胞组织尤其是对免疫细胞体系的毒性而受到制约。因此,本文旨在研究小鼠转基因Apoptin是否在正常淋巴细胞的发育、激活和增殖过程中对其具有干扰性。方法建立H-2K^b启动子表达调控的Apoptin转基因小鼠模型。以Northern和Western印迹法分析Apoptin在转基因小鼠不同组织中的表达。以FACS方法分析Apoptin的表达对B、T淋巴细胞的细胞效应。并以脂多糖(LPS)刺激Apoptin转基因细胞和对照细胞,比较生长曲线。结果 Apoptin主要表达于淋巴组织。重要的是,Apoptin不影响转基因小鼠的B、辅助T或细胞毒T细胞生长数量,提示诸细胞类型对Apoptin凋亡效应的非敏感性。蛋白酶体抑制实验表明,在这些正常细胞中,Apoptin呈短半衰期形式,该现象部分解释了Apoptin的肿瘤特异性机制。此外,LPS对B细胞的激活或IL-2和Con A对T细胞的刺激,不导致转基因淋巴细胞的生长劣势,亦不导致细胞死亡效应的增加。结论 Apoptin转基因小鼠的淋巴细胞在发育和增殖过程中对Apoptin的表达具有耐受性,为发展Apoptin的体系统肿瘤治疗消除了首要障碍。 | Alexandra Pietersen Stefan Erkeland Saskia Rutjes Sjaak Philipsen Jan Paul Medema Mathieu H. M. Noteborn | 2005 | 医学分子生物学杂志2005，2，5： | 1 |
| 8 | Pathology and clinical correlates in oral candidiasis and its variants:a review显示文摘 | Reichart PA Samaranayake LP Philipsen HP | 2000 | OralDis2000，6，2： | 1 |
| 9 | Validity testing of the Dutch translation of the appraisal of self - care agency ASA scale显示文摘 | Evers G Isenberg M Philipsen H | 1993 | International Journal of Nursing Studies1993，30，4： | 1 |
| 10 | Proteomic analysis of the inflamed intestinal mucosa reveals distinctive immune response profiles in Grohn’s disease and ulcerative colitis显示文摘 | Berndt U Bartsch S Philipsen L | 2007 | Immunol2007，179，1： | 1 |
| 11 | Om Keratocyster (kolesteatom) i kaeberne 显示文摘 | Philipsen HP | 1956 | Tandlaegebladet1956，60，： | 1 |
| 12 | Continuous deep sedation for patients nearing death in the Netherlands : descriptive study 显示文摘 | Rietjens J Van Delden J Onwuteaka - Philipsen B | 2008 | BMJ2008，336，7648： | 1 |
| 13 | Validity testing of the Dutch translation of the appraisal of self-care agency ASA Scale 显示文摘 | Evers G Lsenborg M Philipsen H | 1993 | Int J Nurs Studi1993，30，33： | 1 |
| 14 | Calcifying epithelial odontogenic tumor:Biological profile based on 181 cases from the literature显示文摘 | Philipsen HP Reichart PA | 2000 | Oral Oncol2000，36，： | 1 |
| 15 | Detection of Skin Cancer by Classification of Raman Spectra显示文摘 | Sigurdsson S Philipsen P A Hansen L K | 2004 | IEEE Transaction on Biomedical Engineering2004，51，10： | 1 |
| 16 | Peripheral ameloblastoma:biological profile based on 160 cases from the literature显示文摘 | Philipsen H P Reichart P A Nikai H | 2001 | Oral Oncol2001，37，1： | 1 |
| 17 | Borderline typical symp?toms in adult patients with attention deficit/hyperactivity disorder显示文摘 | Philipsen A Feige B Hesslinger B | 2009 | Atten Defic Hyperact Disord2009，1，1： | 1 |
| 18 | Protoporphyrin IX formation after topical application of methyl aminolaevulinate and BF ‐200 aminolaevulinic acid declines with age显示文摘 | C.V. Nissen P.A. Philipsen H.C. Wulf | 2015 | Br J Dermatol2015，，： | 1 |
| 19 | Mammalian SP/KLF transcrip-tion factors: bring in the family 显示文摘 | Suske G Bruford E Philipsen S | 2005 | Genomics2005，85，5： | 1 |
| 20 | Revision of the 1992-edition of the WHO histological typing of odontogenic tumours : a sug- gestion显示文摘 | Philipsen HP Reichart PA | 2002 | J Oral Pathol Med2002，31，5： | 1 |
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