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| 1 | Efficacy of transcatheter embolization/chemoembolization (TAE/TACE) for the treatment of single hepatocellular carcinoma显示文摘AIM:To investigate the efficacy of transcatheter embolization/chemoembolization (TAE/TACE) in cirrhotic patients with single hepatocellular carcinoma (HCC) not suitable for surgical resection and percutaneous ablation therapy. METHODS:A cohort of 176 consecutive cirrhotic patients with single HCC undergoing TAE/TACE was reviewed; 162 patients had at least one image examination (helical CT scan or triphasic contrastenhanced MRI) after treatment and were included into the study. TAE was performed with Lipiodol followed by Gelfoam embolization; TACE was performed with Farmorubicin prepared in sterile drip at a dose of 50 mg/m2,infused over 30 min using a peristaltic pump,and followed by Lipiodol and Gelfoam embolization. RESULTS:Patients characteristics were:mean age,62 years; male/female 117/45; Child-Pugh score 6.2 ± 1.1; MELD 8.7 ± 2.3; mean HCC size,3.6 (range 1.0-12.0) cm. HCC size class was ≤ 2.0 cm,n = 51; 2.1-3.0 cm,n = 35; 3.1-4.0 cm,n = 29; 4.1-5.0 cm,n = 22; 5.1-6.0 cm,n = 11; and > 6.0 cm,n = 14. Patients received a total of 368 TAE/TACE (mean 2.4 ± 1.7). Complete tumor necrosis was obtained in 94 patients (58%),massive (90%-99%) necrosis in 16 patients (10%),partial (50%-89%) necrosis in 18 patients (11%) and poor (< 50%) necrosis in the remaining 34 patients (21%). The rate of complete necrosis according to the HCC size class was:69%,69%,52%,68%,50% and,13% for lesions of ≤ 2.0,2.1-3.0,3.1-4.0,4.1-5.0,5.1-6.0,and > 6.0 cm,respectively. Kaplan-Mayer survival at 24-mo was 88%,68%,59%,59%,45%,and 53% for lesions of ≤ 2.0,2.1-3.0,3.1-4.0,4.1-5.0,5.1-6.0,and > 6.0 cm,respectively. CONCLUSION:Our study showed that in cirrhotic patients with single HCC smaller than 6.0 cm,TAE/TACE produces complete local control of tumor in a significant proportion of patients. TAE/TACE is an effective therapeutic option in patients with single HCC not suitable for surgical resection or percutaneous ablation therapies. Further studies should investigate if the new available embolization agents or drug eluting beads may improve the effect on tumor necrosis. | Roberto Miraglia Giada Pietrosi Luigi Maruzzelli Ioannis Petridis Settimo Caruso Gianluca Marrone Giuseppe Mamone Giovanni Vizzini Angelo Luca Bruno Gridelli | 2007 | World Journal of Gastroenterology2007，13，21： | 38 |
| 2 | Endoscopic treatment of biliary complications after liver transplantation显示文摘AIM:To evaluate the efficacy of endoscopic treatment in patients who undergo OLTx or LRLTx and develop biliary complications. METHODS:This is a prospective, observational study of patients who developed biliary complications, after OLTx and LRLTx, with duct-to-duct anastomosis performed between June 2003 and June 2007. Endoscopic Retrograde Cholangiopancreatography (ERCP) was considered unsuccessful when there was evidence of continuous bile leakage despite endoscopic stent placement, or persistence of stenosis after 1 year, despite multiple dilatation and stent placement. When the ERCP failed, a percutaneous trans-hepatic approach (PTC) or surgery was adopted. RESULTS: From June 2003 to June 2007, 261 adult patients were transplanted in our institute, 68 from living donors and 193 from cadaveric donors. In the OLTx group the rate of complications was 37.3%, while in the LRLTx group was 64.7%. The rate of ERCP failure was 19.4% in the OLTx group and 38.6% in LRLTx group. In OLTx group, 1 patient was re- transplanted and 8 patients died. In the LRLTx group, 2 patients underwent OLTx and 8 patients died. The follow-up was 23.3 ± 13.13 mo and 21.02 ± 14.10 mo, respectively.CONCLUSION: Although ERCP is quite an effective mode of managing post-transplant bile duct complications, a significant number of patients need other types of approach. Further prospective studies are necessary in order to establish whether other endoscopic protocols or new devices, could improve the current results. | Ilaria Tarantino Luca Barresi Ioannis Petridis Riccardo Volpes Mario Traina Bruno Gridelli | 2008 | World Journal of Gastroenterology2008，14，26： | 6 |
| 3 | The effect of platform switching on the levels of metal ion release from different implant–abutment couples显示文摘The improved peri-implant bone response demonstrated by platform switching may be the result of reduced amounts of metal ions released to the surrounding tissues. The aim of this study was to compare the levels of metal ions released from platform-matched and platform-switched implant–abutment couples as a result of accelerated corrosion. Thirty-six titanium alloy(Ti-6Al-4V) and cobalt–chrome alloy abutments were coupled with titanium cylinders forming either platform-switched or platform-matched groups(n = 6). In addition, 18 unconnected samples served as controls. The specimens were subjected to accelerated corrosion by static immersion in 1% lactic acid for 1 week. The amount of metal ions ion of each test tube was measured using inductively coupled plasma mass spectrometry. Scanning electron microscope(SEM) images and energy dispersive spectroscopy X-ray analyses were performed pre- and post-immersion to assess corrosion at the interface. The platform-matched groups demonstrated higher ion release for vanadium, aluminium, cobalt, chrome, and molybdenum compared with the platform-switched groups(Po0.05). Titanium was the highest element to be released regardless of abutment size or connection(Po0.05). SEM images showed pitting corrosion prominent on the outer borders of the implant and abutment platform surfaces. In conclusion, implant–abutment couples underwent an active corrosion process resulting in metal ions release into the surrounding environment. The highest amount of metal ions released was recorded for the platform-matched groups, suggesting that platform-switching concept has a positive effect in reducing the levels of metal ion release from the implant–abutment couples. | Ghada O Alrabeah Jonathan C Knowles Haralampos Petridis | 2016 | International Journal of Oral Science2016，8，2： | 5 |
| 4 | Multimodal teaching,learning and training in virtual reality:a review and case study显示文摘It is becoming increasingly prevalent in digital learning research to encompass an array of different meanings,spaces,processes,and teaching strategies for discerning a global perspective on constructing the student learning experience.Multimodality is an emergent phenomenon that may influence how digital learning is designed,especially when employed in highly interactive and immersive learning environments such as Virtual Reality(VR).VR environments may aid students'efforts to be active learners through consciously attending to,and reflecting on,critique leveraging reflexivity and novel meaning-making most likely to lead to a conceptual change.This paper employs eleven industrial case-studies to highlight the application of multimodal VR-based teaching and training as a pedagogically rich strategy that may be designed,mapped and visualized through distinct VR-design elements and features.The outcomes of the use cases contribute to discern in-VR multimodal teaching as an emerging discourse that couples system design-based paradigms with embodied,situated and reflective praxis in spatial,emotional and temporal VR learning environments. | Stéphanie PHILIPPE Alexis DSOUCHET Petros LAMERAS Panagiotis PETRIDIS Julien CAPORAL Gildas COLDEBOEUF Hadrien DUZAN | 2020 | Virtual Reality & Intelligent Hardware2020，2，5： | 3 |
| 5 | Copper and zinc in four freshwater fish species from Lake Pamvotis (Greece)显示文摘 | I. Papagiannis I. Kagalou J. Leonardos D. Petridis V. Kalfakakou | 2003 | Environment International2003，，3： | 3 |
| 6 | Graphite oxide:Chemical reduction to graphite and surface modification with primary aliphatic amines and amino acids显示文摘 | Bourlinos A B Gournis D Petridis D | 2003 | Langmuir2003，19，15： | 1 |
| 7 | Instrumental analysis of volatile and other compounds of Greek kiwiwine;sensory evaluation and optimization of its composition显示文摘 | SOUFLEROS E H PISSA I PETRIDIS D | 2001 | Food Chemistry2001，75，4： | 1 |
| 8 | A genetic algorithm solution to the unit commitment problem 显示文摘 | KAZARLIS S A BAKIRTZIS A G PETRIDIS V | 1996 | IEEE Trans on Power Systems1996，11，1： | 1 |
| 9 | Nu- tritional Value and Metal Content of Wild Edible Mush- rooms Collected From West Macedonia and Epirus, Greece 显示文摘 | OUZOUNI P K PETRIDIS D RIGANAKOS K A | 2009 | Food Chemistry2009，115，： | 1 |
| 10 | Genetic algo- rithm solution to the economic dispatch problem 显示文摘 | BAKIRTZIS A PETRIDIS V KAZARLIS S | 1994 | IEEE Proceedings-Generation Transmission and Distribution1994，141，4： | 1 |
| 11 | Synthesis and characterization of iron-containing MCM-41 porous silica by the exchange method of the template显示文摘 | BOURLINOS A B KARAKASSIDES M A PETRIDIS D | 2000 | J Phys Chem B2000，104，： | 1 |
| 12 | Use of polysialic acid in repair of the central nervous system显示文摘 | El Maarouf A Petridis AK Rutishauser U | 2006 | Proc Natl Acad Sci USA2006，103，16： | 1 |
| 13 | Formation of hydroxyl Catalyzed by clay surfaces 显示文摘 | Gournis D Karakassides M A Petridis D | 2002 | Phy Chem Minerals2002，29，： | 1 |
| 14 | Biogenic amines in fish and soyces 显示文摘 | Stute R Petridis K Steinhart H | 2002 | European Food Research and Tech- nology2002，215，2： | 1 |
| 15 | Learning in the framework of fuzzy lattices显示文摘 | V Petridis V G Kaburlasos | 1999 | IEEE Transactions on Fuzzy Systems1999，7，4： | 1 |
| 16 | Second primary neoplasms in patients with laryngeal carcinoma显示文摘 | Nikolaou AC Markou CD Petridis DG | | 0，，01： | 1 |
| 17 | Fuzzy lattice netaxeompuling (FLN) models显示文摘 | V G Kaburlasos V Petridis | 2000 | Neural Networks2000，13，10： | 1 |
| 18 | A genetic algorithm solution to the unit commitment problem显示文摘 | Kazarlis S A Bakirtzis A G Petridis V | | 0，，01： | 1 |
| 19 | Amifostine reduces radiochemothemotherapy-induced toxicities in patients with locally advanced non small cell lung cancer显示文摘 | Antonadou D Petridis A Synodinou M | 2003 | Semin Oncol2003，30，6： | 1 |
| 20 | A genetic algorithm solution to the unit commitment problem显示文摘 | Kazarlis S A Bakitrtzis A G Petridis V | 1996 | IEEE Transactions Power Systems1996，11，1： | 1 |
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