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| 1 | Assessment of oxidative stress in chronic pancreatitis patients显示文摘AIM: To assess the levels of antioxidant capacity and oxidative damage in blood of chronic pancreatitis (CP) patients in comparison with those in healthy control sub- jects, by using several different analytical techniques. METHODS: Thirty-five CP patients and 35 healthy con- trol subjects were investigated prospectively with re- spect to plasma levels of thiols, ferric reducing ability of plasma (FRAP, i.e. antioxidant capacity), levels of protein carbonyls and thiobarbituric acid reactive substances (TBARS). Additionally, we evaluated the production of reactive oxygen species (ROS) in whole blood. RESULTS: The antioxidative thiols including cysteine, cysteinylglycine and glutathione were significantly lower in CP patients. In addition, the non-enzymatic antioxi- dant capacity was significantly lower in CP patients, which correlated with the amount of oxidative protein (protein carbonyls) and the extent of lipid damage (TBARS), both were significantly higher in CP patients. The ROS production in whole blood after stimulation with phorbol 12-myritate 13-acetaat, demonstrated a strong tendency to produce more ROS in CP patients. CONCLUSION: Oxidative stress may contribute to the pathogenesis of chronic pancreatitis by decreasing anti- oxidant capacity and increasing oxidative damage in CP patients may be a rationale for intervention with antioxi- dant therapy. | Mariette Verlaan Hennie MJ Roelofs Annie van Schaik Geert JA Wanten Jan BMJ Jansen Wilbert HM Peters Joost PH Drenth | 2006 | World Journal of Gastroenterology2006，12，35： | 3 |
| 2 | Mirizzi syndrome显示文摘 | Toscano RL Taylor PH Peters J | 1994 | Am Surg1994，60，11： | 1 |
| 3 | Indications of nonlin- ear deterministic and finite - dimensional structures in time series of brain electrical activity: Dependence on recording region and brain state显示文摘 | Ralph G Andrzejak Klaus Lehnertz Florian Mormann Christo- ph Rieke Peter David Christian E Elger | 2001 | Physical Review E2001，64，06： | 1 |
| 4 | The CD95 (APO21/ Fas) DISC and beyond 显示文摘 | Peter ME Krammer PH | 2003 | Cell Death Differ2003，10，： | 1 |
| 5 | A meta analysis of treatment outcomes of early enteral versus early parenteral nutrition in hospitalized patients显示文摘 | Peter JV Moran JL Jennie PH | 2005 | Crit Care Med2005，33，1： | 1 |
| 6 | A meta analysis of treatmentoutcomes of early enteral versus early parenteral nutrition inhospitalized patients显示文摘 | Peter JV Moran JL Jennie PH | 2005 | Crit Care Med2005，33，： | 1 |
| 7 | Pyelitis in toxemias of pregnancy 显示文摘 | Peters JP Lavietes PH Zinnerman HM | 1936 | AM J Obstet Gynecol1936，32，： | 1 |
| 8 | A meta analysis of treatment outeomes of early enteral versus early parenteral nutrition in hospitalized patients显示文摘 | Peter JV Moran JL Jennie PH | 2005 | Crit Care Med2005，33，1： | 1 |
| 9 | The CD95 (AP0-1/Fas) DISC and beyond 显示文摘 | Peter ME Krammer PH | 2003 | Cell Death Differ2003，10，1： | 1 |
| 10 | Mirizzi syndrome显示文摘 | Toscano RL Taylor PH Jr Peters J | 1994 | Am Surg1994，60，11： | 1 |
| 11 | The CD95 (APO-1/Fas) DISC and beyond显示文摘 | Peter ME Krammer PH | 2003 | Cell Death Differ2003，10，1： | 1 |
| 12 | A chamber to permit invasive manipulation of adherent cells in laminar flow with minimal disturbance of the flow field显示文摘 | Irena L Brian PH Peter FD | 2000 | Annals of Biomedical Engineering2000，28，： | 1 |
| 13 | Design and num- berical implementation of a 3-D non-linear viscoelastic consti- tutive model for brain tissue during impact 显示文摘 | Brands DW Peters GW Bovendeerd PH | 2004 | J Biomech2004，37，1： | 1 |
| 14 | The MRP4/ABCC4 geneencodes a novel apical organic anion transporter in human kidneyproximal tubules: putative efflux pump for urinary cAMP and cGMP显示文摘 | Van Aubel RA Smeets PH Peters JG | 2002 | Am Soc Nephrol2002，13，3： | 1 |
| 15 | Regional and hormone-dependent effects of apolipopritein E genotype on changes in bone minend in perimenopausal women显示文摘 | Lars UG Peter V Anne PH | 2001 | Bone Miner Res2001，，： | 1 |
| 16 | A metaanalysis of treatment outcomes of early enteral versus early parenteral nutrition inhospitalized patients显示文摘 | Peter JV Moran JL Jennie PH | 2005 | Crit Care Med2005，33，： | 1 |
| 17 | The CD95 (APO-1/Fas) DISC and beyond显示文摘 | PETER ME KRAMMER PH | | 0，，01： | 1 |
| 18 | New transcranial Doppler index in infants with hydrocephalus:transsystolic time in clinical practice显示文摘 | Leliefeld PH Gooskens RH Peters RJ | 2009 | Ultrasound Med Biol2009，35，10： | 1 |
| 19 | Labat法坐骨神经阻滞下局部麻醉药低容量高浓度较高容量低浓度更有效:一项前瞻性随机对照研究显示文摘背景有很多因素可以明显影响外周神经阻滞的起效时间和成功率,本项前瞻、随机、双盲研究比较了Labat后路法行坐骨神经阻滞时,单剂量的甲哌卡因300mg分别稀释至20和30ml注射后的阻滞效果差异。方法90例行足部手术的患者,随机分为2组接受坐骨神经阻滞,一组给予1.5%甲哌卡因20m1(45例),另一组给予1%甲哌卡因30m1(45例),所有阻滞均在神经刺激仪定位下进行(参数为刺激频率2Hz;刺激电流为1.5~0.5mA)。两组中,神经刺激反应在〈0.5mA时引出,亦可以定向诱发足部肌肉向跖侧屈曲,分别记录胫神经和腓总神经的运动感觉功能被阻滞的起效时间。而坐骨神经支配区域的针刺感觉消失,同时足部跖曲及背曲运动消失为阻滞成功的标准。结果用20ml的1.5%甲哌卡因组阻滞成功率(96.6%)显著高于30ml的1%甲哌卡因组(68.9%,P〈0.05)。而前者达到感觉与运动完全阻滞所需要的时间(11±6分钟,13±7分钟)也短于后者(17±8分钟,19±8分钟,P〈0.05)。结论Labat法行坐骨神经阻滞时,与高容量低浓度的局部麻醉药(1%甲哌卡因)比较,使用低容量高浓度的局部麻醉药(1.5%甲哌卡因)能够获得更高的阻滞成功率及更短的起效时间。 | Manuel Taboada Muniz, MD, PhD Jaime Rodriguez, MD, PhD Maria Bermudez, MD Cristina Valino, MD Noemi Blanco, MD Marcos Amor, MD Pilar, Aguirre, MD Ana Masid, MD Joaquin Cortes, MD, Ph Julian Alvarez, MD, PhD Peter G. Atanassoff, MD 杨光(译) 崔苏扬(校) | 2010 | 麻醉与镇痛2010，，2： | 1 |
| 20 | A meta analysis of treatment outcomes of early entcral versus early parenteral nutrition in hospitalized patients显示文摘 | Peter JV Moran JL Jennie PH | 2005 | Crit Care Med2005，33，1： | 1 |
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