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| 1 | Combined administration of platelet rich plasma and autologous bone marrow aspirate concentrate for spinal cord injury: a descriptive case series显示文摘Administration of platelet rich plasma(PRP) and bone marrow aspirate concentrate(BMAC) has shown some promise in the treatment of neurological conditions;however, there is limited information on combined administration. As such, the purpose of this study was to assess safety and functional outcomes for patients administered combined autologous PRP and BMAC for spinal cord injury(SCI). This retrospective case series included seven patients who received combined treatment of autologous PRP and BMAC via intravenous and intrathecal administration as salvage therapy for SCI. Patients were reviewed for adverse reactions and clinical outcomes using the Oswestry Disability Index(ODI) for up to 1 year, as permitted by availability of follow-up data. Injury levels ranged from C3 through T11, and elapsed time between injury and salvage therapy ranged from 2.4 months to 6.2 years. Post-procedure complications were mild and rare, consisting only of self-limited headache and subjective memory impairment in one patient. Four patients experienced severe disability prior to PRP combined with BMAC injection, as evidenced by high(> 48/100) Oswestry Disability Index scores. Longitudinal Oswestry Disability Index scores for two patients with incomplete SCI at C6 and C7, both of whom had cervical spine injuries, demonstrated a decrease of 28–40% following salvage therapy, representing an improvement from severe to minimal disability. In conclusion, intrathecal/intravenous co-administration of PRP and BMAC resulted in no significant complications and may have had some clinical benefits. Larger clinical studies are needed to further test this method of treatment for patients with SCI who otherwise have limited meaningful treatment options. This study was reviewed and approved by the Ohio Health Institutional Review Board(IRB No. 1204946) on May 16, 2018. | Joseph A.Shehadi Steven M.Elzein Paul Beery M.Chance Spalding Michelle Pershing | 2021 | Neural Regeneration Research2021，16，2： | 3 |
| 2 | Char nitrogen conversion: implications to emissions from coal-fired utility boilers显示文摘 | A. Molina E.G. Eddings D.W. Pershing A.F. Sarofim | 2000 | Progress in Energy and Combustion Science2000，，4： | 2 |
| 3 | Nonliner theory of the Free electron laser based upon a coaxial hybrid wiggler显示文摘 | Freund H P Jackson R H Pershing D E | 1994 | Phys Plasmas1994，1，4： | 2 |
| 4 | Comparison of dermatopharmacokinetic vs clinicial efficacy methods for bioequivalenee assessment of miconazole nitrate vaginal cream, 2% in humans 显示文摘 | PERSHING L K CORLETT J L NELSON J L | 2002 | Pharm Res2002，19，3： | 1 |
| 5 | A Mathemat ical Model for the Flash Calcinations of Dispersed CaCO3 and Ca(OH)2 Particl es显示文摘 | Silicox G D Kramlica J C Pershing D W | 1989 | Ind Eng Chem Res1989，28，： | 1 |
| 6 | Nitric oxide destruction during coal and char oxidation under pulverized-coal combustion conditions显示文摘 | MOLINA A EDDINGS E G PERSHING D W SAROFIM A F | 2004 | Combust Flame2004，136，： | 1 |
| 7 | Char nitrogen conversion: implications to emissions from coal-fired utility boilers 显示文摘 | Molina A Eddings E G Pershing D W | 2000 | Progress in Energy and Combustion Science2000，26，46： | 1 |
| 8 | The fate of char-N at pulverized coal conditions显示文摘 | SpintiJ P Pershing D W | 2003 | Combustion and Flame2003，135，3： | 1 |
| 9 | Band width extension of an S band fundamental mode eight beam klystron显示文摘 | Nguyen K T Pershing D E Abe D K | 2006 | IEEE Transactions on Plasma Science2006，34，3： | 1 |
| 10 | Assessment of topical corticosteroid-induced skin blanching response using the visual Mckenzie-Stoughton and colorimetric methods显示文摘 | | 1995 | Drug Info J1995，29，： | 1 |
| 11 | A mathematical model for the flash calcinations of dispersed CaCO3 and Ca(OH)2 pattides显示文摘 | SILCOX G D KRAMLICH J C PERSHING D W | 1989 | Ind Engng Chem Res1989，28，： | 1 |
| 12 | Physical mechanisms governing the oxidation of volatile fuel nitrogen in pulverized coal显示文摘 | Wendt J O L Pershing D W | 1977 | Flames Combustion Science and Technology1977，149，16： | 1 |
| 13 | Comparison of anterior vitrectorhexis and continuous eurvilinear capsulorhexis in pediatric cataract and intraoeular lens implantation surgery: a 10-year analysis 显示文摘 | Wilson ME Jr Trivedi RH Bartholomew LR Pershing S | 2007 | J AAPOS2007，11，5： | 1 |
| 14 | Char nitrogen conversion: implications to emissions from coal- fired utility boilers 显示文摘 | Molina A Eddings EG Pershing DW | 2000 | Progress in Energy and Combustion Science2000，26，46： | 1 |
| 15 | Char nitrogen conversion: implications to emissions from coal-fired utility boilers显示文摘 | MOLINA A EDDINGS E G PERSHING D W | 2000 | Progress in Energy and Combustion Science2000，26，46： | 1 |
| 16 | A methodology for ana-lyzing availability weak points in SOA deployment frame-works显示文摘 | Luo Jing Li Ying Pershing J A | 2009 | IEEE Transactions on Network and service Man-agement2009，6，1： | 1 |
| 17 | To Snitch or Not to Snitch? Applying the Conceptof Neutralization Techniques to the Enforcement of Occupational Misconduct显示文摘 | Pershing J L | 2003 | Sociological Perspectives2003，46，2： | 1 |
| 18 | Relative Contributions of Volatile Nitrogen and Char Nitrogen to NOx Emissions from Pulverized Coal Flames显示文摘 | Wendt J O L | 1979 | Industrial and Engineering Chemistry Process Design and Development1979，18，1： | 1 |
| 19 | Bandwidth Extension of an S-Band Fundamental-Mode Eight-Beam Klystron显示文摘 | Nguyen K T Pershing D E Abe D K Abe D K | 2006 | IEEE Trans Plasma Sci2006，34，3： | 1 |
| 20 | Emissions of metal and organic compounds from cement kilns using waste derived fuels 显示文摘 | Sarofim A F Pershing D W Dellinger B | 1994 | Hazardous Waste and Hazardous Materials1994，，11： | 1 |
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