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1篇 您的检索式:作者名="Permender Rathee"
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1In-vitro cytotoxic activity of β-Sitosterol triacontenate isolated from Capparis decidua(Forsk.) Edgew显示文摘Objective:To study the isolation and characterization of the constituent responsible for the cytotoxic activity of the ethanolic extract of stem of Capparis decidua(C.decidua).Methods:The preliminary cytotoxic effect of isolated compound(β-Sitosterol triacontenate) was investigated by MTT assay on A549 solid tumor cells.Results:IC50 value of theβ-Sitosterol triacontenate was found to be 1μM.The cytotoxic activity increased in a dose dependent manner in case ofβ-Sitosterol triacontenate.Conclusions:The data therefore provide direct evidence for the role ofβ-Sitosterol triacontenate as a potent antimetastatic agent,which can markedly inhibit the metastatic and invasive capacity of malignant cells.Permender Rathee Dharmender Rathee Deepti Rathee Sushila Rathee 2012Asian Pacific Journal of Tropical Medicine2012,5,3:5
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