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| 1 | Oleanolic Acid Induces Apoptosis in Human Leukemia Cells through Caspase Activation and Poly(ADP-ribose) Polymerase Cleavage显示文摘它被看了那 Fructus Ligustri Lucidi (FLL ) ,有希望的 traditionalChinesemedicine,能禁止肿瘤的生长。然而,有效部件和 FLL 的分子的机制行动禁止肿瘤增长是不清楚的。在这研究,我们表明了 thatoleanolic 酸(OA ) , FLL 的一个主要化学部件,在文化禁止了人的白血病 HL60 房间的增长。MTT 试金与 FLL 粗略的摘录显示出 HL60 细胞的那个处理或 OA 戏剧性地在 time-dependentmanner 和 dose-dependentmanner 堵住了目标肿瘤房间的生长。原子核和 DNA 破碎的词法变化证明 apoptotic 房间死亡在与 FLL 摘录(20 mg/ml ) 或 OA 对待以后发生在 HL60 房间(3.65xl0 ^(-2) mg/ml ) 。而且,流动 cytometry 试金与 FLL 显示出 HL60 房间的那个处理或 OA 引起了 G1 和 sub-G1 潜水艇人口的增加的累积。蛋白质印迹分析证明 caspase-9and caspase-3 被激活,由劈开伴随了 poly (自动数据处理核糖) 在目标房间的聚合酶(PARP ) 在导致 FLL 或导致 OA 的 apoptosis 期间。这些结果建议 OA 由通过 caspases 的激活和 PARP 的劈开向目标肿瘤房间施加它的 cytotoxicity 充当 FLL 的有效部件。 | Pengxia ZHANG Hongmei LI Dong CHEN Juhua NI Yuming KANG Shuqiu WANG | 2007 | Acta Biochimica et Biophysica Sinica2007，39，10： | 26 |
| 2 | Aurora A orchestrates entosis by regulating a dynamic MCAK-TIP150 interaction显示文摘 | PengXia JinhuaZhou Xiaoyu Song BingWu XingLiu Di Li Shuyuan Zhang Zhikai Wang H uijuan Yu Tarsha Ward Jiancun Zhang Yinmei Li Xiaoning Wang YongChen Zhen Guo Xuebiao Yao | 2014 | Journal of Molecular Cell Biology2014，8，3： | 9 |
| 3 | Climatology and seasonal variability of satellite-derived chlorophyll a around the Shandong Peninsula显示文摘The chlorophyll a(Chl a)is an important indicator of marine ecosystems.The spatiotemporal variation of the Chl a greatly aff ects the mariculture and marine ranching in coastal waters of the Shandong Peninsula.In the current study,the climatology and seasonal variability of surface Chl-a concentration around the Shandong Peninsula are investigated based on 16 years(December 2002-November 2018)of satellite observations.The results indicate that the annual mean Chl-a concentration is greater in the Bohai Sea than in the Yellow Sea and decreases from coastal waters to off shore waters.The highest Chl-a concentrations are found in Laizhou Bay(4.2-8.0 mg/m^(3)),Haizhou Bay(4.2-5.9 mg/m^(3))and the northeast coast of the Shandong Peninsula(4.4-5.0 mg/m^(3)),resulting from the combined eff ects of the intense riverine input and long residence time caused by the concave shape of the coastline.The seasonal Chl-a concentration shows a significant spatial variation.The Chl-a concentrations in these three subregions generally exhibit an annual maximum in August/September,due to the combined eff ects of sea surface temperature,river discharge and sea surface wind.In the southeast coast region,however,the Chl-a concentration is lowest throughout the year and reaches a maximum in February with a minimum in July,forced by the seasonal evolution of the Yellow Sea Cold Water and monsoon winds.The interannual Chl-a concentration trends vary among regions and seasons.There are significant increasing trends over a large area around Haizhou Bay from winter to summer,which are mainly caused by the rising sea surface temperature and eutrophication.In other coastal areas,the Chl-a concentration shows decreasing trends,which are clearest in summer and induced by the weakening land rainfall.This study highlights the differences in the Chl-a dynamics among regions around the Shandong Peninsula and is helpful for further studies of coupled physical-ecological-human interactions at multiple scales. | Xiukai SONG Yanzhen GU Fangguo ZHAI Peiliang LI Pengxia LIU Zizhou LIU Wenfan WU Yaozu CHEN Xiangyang JIANG Jianlong HE | 2021 | Journal of Oceanology and Limnology2021，39，4： | 3 |
| 4 | High carbon dioxide and low oxygen storage effects on reactive oxygen species metabolism in Pleurotus eryngii显示文摘 | Pengxia Li Xuan Zhang Huali Hu Ya Sun Yuning Wang Yancun Zhao | 2013 | Postharvest Biology and Technology2013，，： | 1 |
| 5 | Control of postharvest soft rot caused by Erwinia carotovora of vegetables by a strain of Bacillus amyloliquefaciens and its potential modes of action显示文摘 | ZHAO Yancun LI Pengxia HUANG Kaihong | | 0，，： | 1 |
| 6 | Control of postharvest soft rot caused by Erwinia carotovora of vegetables by a strain of Bacillus amyloliquefaciens and its potential modes of action显示文摘 | Zhao Yancun Li Pengxia Huang Kaihong | 2013 | World Journal of Microbiol- ogy and Biotechnology2013，29，3： | 1 |
| 7 | Development and Characterization of Acellular Porcine Corneal Matrix Using Sodium Dodecylsulfate显示文摘 | Yang Zhou Zheng Wu Jian Ge Pengxia Wan Naiyang Li Peng Xiang Qianying Gao Zhichong Wang | 2011 | Cornea2011，，1： | 1 |
| 8 | Control of postharvest soft rot caused by Erwinia carotovora of vegetables by a strain of Bacillus amyloliquefaciens and its potential modes of action显示文摘 | ZHAOhao Yancun LI Pengxia HUANG Kaihong | 2013 | World Journal of Microbiology and Biotechnology2013，29，： | 1 |
| 9 | Design of low power 4×40 Gb/s laser diode driver for parallel optical transmission systems显示文摘Compared with conventional electrical interconnection technology,optical interconnection has the merits of anti-interference,small signal loss,long transmission distance and so on.Furthermore,parallel optical interconnects become the crucial technique to solve the problem of large capacity data transmission in high-speed transmission systems.The parallel mode can decrease transmit rate of every optical fiber,reduce the demands for optical devices and decrease the cost of optical interconnects[1–3]. | Yingmei CHEN Zhen ZHANG Jiquan LI Hui WANG Pengxia WANG Yanwei LI | 2017 | Science China(Information Sciences)2017，60，8： | 0 |
| 10 | Hybrid ionic/electronic interphase enabling uniform nucleation and fast diffusion kinetics for stable lithium metal anode显示文摘Lithium(Li)dendrite issue,which is usually caused by inhomogeneous Li nucleation and fragile solid electrolyte interphase(SEI),impedes the further development of high-energy Li metal batteries.However,the integrated construction of a high-stable SEI layer that can regulate uniform nucleation and facilitate fast Li-ion diffusion kinetics for Li metal anode still falls short.Herein,we designed an artificial SEI with hybrid ionic/electronic interphase to regulate Li deposition by in-situ constructing metal Co clusters embedded in LiF matrix.The generated Co and LiF both enable fast Li-ion diffusion kinetics,meanwhile,the lithiophilic properties of Co clusters can serve as Li-ion nucleation sites,thereby contributing to uniform Li nucleation and non-dendritic growth.As a result,a dendrite-free Li deposition with a low overpotential(16.1 mV)is achieved,which enables an extended lifespan over 750 h under strict conditions.The full cells with high-mass-loading LiFePO_(4)(11.5 mg/cm^(2))as cathodes exhibit a remarkable rate capacity of 84.1 mAh/g at 5 C and an improved cycling performance with a capacity retention of 96.4%after undergoing 180 cycles. | Lun Li Pengxia Ji Meng Huang Zixin Zhang Hong Wang Francis Verpoort Jinlong Yang Daping He | 2024 | Chinese Chemical Letters2024，35，2： | 0 |
| 11 | Spatiotemporal variations in the organic carbon accumulation rate in mangrove sediments from the Yingluo Bay,China,since 1900显示文摘Mangroves can not only provide multiple ecosystem service functions,but are also efficient carbon producers,capturers,and sinks.The estimation of the organic carbon accumulation rate(OCAR)in mangrove sediments is fundamental for elucidating the role of mangroves in the global carbon budget.In particular,understanding the past changes in the OCAR in mangrove sediments is vital for predicting the future role of mangroves in the rapidly changing environment.In this study,three dated sediment cores from interior and fringe of mangroves in the Yingluo Bay,China,were used to reconstruct the spatiotemporal variations of the calculated OCAR since 1900 in this area.The increasing OCAR in the mangrove interior was attributed to mangrove flourishment induced by climate change characterized by the rising temperature.However,in the mangrove fringe,the strengthening hydrodynamic conditions under the sea level rise were responsible for the decreasing OCAR,particularly after the1940 s.Furthermore,the duration of inundation by seawater was the primary factors controlling the spatial variability of the OCAR from the mangrove fringe to interior,while the strengthened hydrodynamic conditions after the 1940 s broke this original pattern. | Yao Zhang Xianwei Meng PengXia Jun Zhang Dahai Liu Zhen Li Wanzhu Wang | 2021 | Acta Oceanologica Sinica2021，40，8： | 0 |
| 12 | Melatonin delays leaf senescence in pak choi(Brassica rapa subsp.chinensis)by regulating biosynthesis of the second messenger cGMP显示文摘Melatonin(MT)is a low molecular weight compound with multiple biological functions in plants.It is known to delay leaf senescence in various species.However,no data are available on the MT signaling pathway in postharvest vegetables.This study demonstrates that MT increases cGMP concentration and the expression of the cGMP synthesis gene BcGC1 in pak choi.The c GMP inhibitor LY83583 destroys effect of MT delaying the leaf senescence.LY83583 also prevents MT treatment from reducing the expression of chlorophyll metabolism-related genes(BcNYC1,BcNOL,BcPPH1/2,BcSGR1/2,and BcPAO)and senescence genes(BcSAG12 and BcSAG21).It also inhibits MT from reducing the activity of the key chlorophyll catabolism enzymes Mg-dechelatase,pheophytinase,and pheide a oxygenase.Thus,the ability of MT to maintain high levels of chlorophyll metabolites is also destroyed.The Arabidopsis c GMP synthetic gene mutant atgc1 was used to confirm that delayed leaf senescence caused by MT is mediated,at least in part,by the second messenger c GMP. | Xuesong Liu Ronghui An Guofeng Li Shufen Luo Huali Hu Pengxia Li | 2024 | Horticultural Plant Journal2024，10，1： | 0 |
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