2篇
您的检索式：作者名="Penglong Li"
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| 1 | Baicalin and rutin are major constituents in Shuanghuanglian injection involving anaphylactoid reaction显示文摘OBJECTIVE: To identify the constituents in Shuanghuanglian injection(SHLI) that correlate with anaphylactoid reaction.METHODS: Chemical fingerprints of 10 batches SHLI samples were determined by High Performance Liquid Chromatography(HPLC), and further investigated by similarity analysis. Combined with optical microscopy, both anaphylactoid experiments and confirmatory assay were displayed in Rat basophil leukemia cells(RBL-2H3) to obtain the histamine release inducing by SHLI. The content of histamine was tested by Enzyme-Linked Immuno Sorbent As-say method. Partial least squares regression(PLSR)method and HPLC-DAD-ESI-MSntechnology were conducted to analyze constituents in SHLI involving anaphylactoid reaction.RESULTS: The results of spectrum and effect relationships showed that the eight constituents were positively correlated with anaphylactoid reaction.Among which, nearly 90% of them were identified as baicalin and rutin with PLSR and HPLC-DAD-ESI-MSn. This result was in accordance with confirmatory assay on RBL-2H3 cells.CONCLUSION: Baicalin and rutin from SHLI were the main constituents involving anaphylactoid reaction. | Zhang Qi Cai Chengke Li Jian Wang Penglong Si Yinchu Ding Nan Gao Jing Zhang Yanqiu Ma Zhiqiang Lei Haimin Li Qiang | 2017 | Journal of Traditional Chinese Medicine2017，37，3： | 6 |
| 2 | Research on damage failure mechanism and dynamic mechanical behavior of layered shale with different angles under confining pressure显示文摘The hydrostatic or confining pressure of deep rocks has a significant impact on the mechanical behavior of brittle materials.Especially when confining pressure is applied,the mechanical properties of rock materials will undergo significant changes.Considering that the process of shale sample subjected to impact load is in a closed container in the dynamic triaxial SHPB test,the failure process of the sample cannot be observed.Meanwhile,the activation volume of the shale sample would be large and local failure would occur in the test under the high strain rate loading.Therefore,thefinite element model of shale considering the bedding effect under confining pressure was established in this study.Taking shale materials with different bedding dip angles as simulation objects,the dynamic failure characteristics of shale were studied using the dynamic analysis software ANSYS/LS‐DYNA from three aspects:stress‐strain curve,failure growth process,and failure morphology.The research results obtained can serve as the key technical parameters for deep resource extraction. | Ning Luo Haohao Zhang Yabo Chai Penglong Li Cheng Zhai Jianan Zhou Tianran Ma | 2023 | Deep Underground Science and Engineering2023，2，4： | 0 |
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