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12篇 您的检索式：作者名="Paulo CS"

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		题名	作者	年代	出处	被引量
	1	IL-2 and IL-21 confer opposing differentiation programs to CD8 ^+ T cells for adoptive immunotherapy 显示文摘	Hinrichs CS Spolski R Paulos CM	2008	Blood2008，111，11：	1
	2	Dispersal of Aedes aegypti and Aedes albopictus (Diptera: Culicidae) in an Urban Endemic Dengue Area in the State of Rio de Janeiro, Brazil显示文摘	Nildimar AH Wellington CS Paulo JL	2003	Rio de Janeiro2003，98，：	1
	3	Type 17 CD8+T cells display enhanced anti-tumor immunity显示文摘	Hinrichs CS Kaiser A Paulos CM	2009	Blood2009，114，：	1
	4	Type 17 CD8+ T cells display enhanced antitumor immunity 显示文摘	Hinrichs CS Kaiser A Paulos CM	2009	Blood2009，114，3：	1
	5	Bedside transpyloric tube placement in the pediatric in-tensive care unit:a modified insufflation air technique显示文摘	Da Silva PS Paulo CS De Oliveira Iglesias SB	2002	Intensive Care Med2002，28，7：	1
	6	IL-2 and IL-21 confer opposing differentiation programs to CD8 + T ceils for adoptive immunotherapy显示文摘	Hinrichs CS Spolski R Paulos CM	2008	Blood2008，111，11：	1
	7	IL-2 and IL-21 confer opposing differentiation programs to CD8 for adoptive immunotherapy显示文摘	Hinrichs CS Spolski R Paulos CM	2008	Blood2008，111，11：	1
	8	IL-2 and IL-21 confer opposing differentiation programs to CD8^+ T cells for adoptive immunotherapy 显示文摘	Hinrichs CS Spolski R Paulos CM	2008	Blood2008，111，：	1
	9	Type 17 CD8+ T cells display enhanced antitumor immunity 显示文摘	Hinrichs CS Kaiser A Paulos CM	2009	Blood2009，114，3：	1
	10	Differential internalization of amphotericin B-conjugated nanoparticles in human cells and the expression of heat shock protein 70显示文摘	Paulo CS Lino MM Matos AA	2013	Biomaterials2013，34，21：	1
	11	Type 17CD8+T cells display enhanced antitumor immunity显示文摘	Hinrichs CS Kaiser A Paulos CM	2009	Blood2009，114，：	1
	12	Restoration of Motor Function through Delayed Intraspinal Delivery of Human IL-10-Encoding Nucleoside-Modified mRNA after Spinal Cord Injury显示文摘Efficient in vivo delivery of anti-inflammatory proteins to modulate the microenvironment of an injured spinal cord and promote neuroprotection and functional recovery is a great challenge.Nucleoside-modified messenger RNA(mRNA)has become a promising new modality that can be utilized for the safe and efficient delivery of therapeutic proteins.Here,we used lipid nanoparticle(LNP)-encapsulated human interleukin-10(hIL-10)-encoding nucleoside-modified mRNA to induce neuroprotection and functional recovery following rat spinal cord contusion injury.Intralesional administration of hIL-10 mRNA-LNP to rats led to a remarkable reduction of the microglia/macrophage reaction in the injured spinal segment and induced significant functional recovery compared to controls.Furthermore,hIL-10 mRNA treatment induced increased expression in tissue inhibitor of matrix metalloproteinase 1 and ciliary neurotrophic factor levels in the affected spinal segment indicating a time-delayed secondary effect of IL-105 d after injection.Our results suggest that treatment with nucleoside-modified mRNAs encoding neuroprotective factors is an effective strategy for spinal cord injury repair.	LászlóGál Tamás Bellák Annamária Marton Zoltán Fekécs Drew Weissman Dénes Török Rachana Biju Csaba Vizler Rebeka Kristóf Mitchell B.Beattie Paulo J.C.Lin Norbert Pardi Antal Nógrádi Krisztián Pajer	2023	Research2023，，4：	0

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