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| 1 | Adipokines and ghrelin in gastric cancer cachexia显示文摘AIM:To investigate the roles of the adipocytokines,ghrelin and leptin in gastric cancer cachexia. METHODS:Resistin,ghrelin,leptin,adiponectin,insulin and insulin-like growth factor(IGF-Ⅰ),were measured in 30 healthy subjects,and 60 gastric cancer patients of which 30 suffered from cancer-induced cachexia and 30 served as a control group. The relationships between hormones,body mass index(BMI) loss ratio,age,gender,and Glasgow Prognostic Score(GPS) were investigated. RESULTS:Cachexia patients had higher tumor stage and GPS when compared with non-cachexia patients(P < 0.05). Ghrelin,resistin,leptin,adiponectin and IGF-Ⅰ,showed a significant correlation with BMI loss ratio and GPS(P < 0.05). A strong correlation was seen between GPS and BMI loss(R = -0.570,P < 0.0001). Multivariate analysis indicated that BMI loss was significantly independent as a predictor of ghrelin,resistin,leptin and IGF-Ⅰ(P < 0.05). Existence of an important significant relationship between resistin and insulin resistance was also noted. CONCLUSION:These results showed that serum ghrelin,leptin,adiponectin,and IGF-Ⅰ play important roles in cachexia-related gastric cancers. No relationshipwas found between resistin and cancer cachexia. Also,because of the correlation between these parameters and GPS,these parameters might be used as a predictor factor. | Mustafa Kerem Zafer Ferahkose Utku Tonguc Yilmaz Hatice Pasaoglu Ebru Ofluoglu Abdulkadir Bedirli Bulent Salman Tevfik Tolga Sahin Murat Akin | 2008 | World Journal of Gastroenterology2008，14，23： | 4 |
| 2 | Agenesis of the dorsal pancreas显示文摘Developmental anomalies of the pancreas have been reported but dorsal pancreatic agenesis is an extremely rare entity. We report an asymptomatic 62-year-old woman with complete agenesis of the dorsal pancreas. Abdominal computed tomography (CT) revealed a normal pancreatic head, but pancreatic body and tail were not visualized. Magnetic resonance imaging (MRI) findings were similar to CT. At magnetic resonance cholangiopancreatography (MRCP), the major pancreatic duct was short and the dorsal pancreatic duct was not visualized. The final diagnosis was dorsal pancreatic agenesis. | Lale Pasaoglu Murat Vural Hatice Gul Hatipoglu Gokce Tereklioglu Suha Koparal | 2008 | World Journal of Gastroenterology2008，14，18： | 3 |
| 3 | Improved heart preservation with UW preservation solution显示文摘 | SWANSON K D PASAOGLU I MANOS G F | 1988 | J Heart Transplant1988，7，2： | 1 |
| 4 | Extradural hematoma of the posterior cranial fossa显示文摘 | Pasaoglu A Menku A | 1998 | Neurosurg Rev1998，21，1： | 1 |
| 5 | Role of ghrelin and leptin in predicting the severity of acute pancreatitis 显示文摘 | Kerem M Bedirlia A Pasaoglu H | 2007 | Dig Dis Sci2007，52，4： | 1 |
| 6 | Extradural hematoma of the posterior cranial fossa显示文摘 | Pasaoglu A Menku A | 1998 | Neurosurg Rev1998，21，1： | 1 |
| 7 | Perioperative hyperglycemia is a strong correlate of postoperative infection in type Ⅱ diabetic patients after coronary artery bypass grafting显示文摘 | Guvener M Pasaoglu I Demircin M | 2002 | Endocr J2002，49，5： | 1 |
| 8 | The effects of caffeine on L-arginine metabolism in the brain of rats 显示文摘 | Ofluoglu E Pasaoglu H Pasaoglu A | 2009 | Neurochem Res2009，34，3： | 1 |
| 9 | Analyses of serum vitamin D-binding protein, eeruloplasmin and copper levels in preterm infants显示文摘 | Pasaoglu H Kurtoglu S Muhtaroglu S | 1992 | The Turkish Journal of Pediatrics1992，34，： | 1 |
| 10 | Atrial fibrillation after coronary artery bypass surgery: predictors and the role of MgSO4 replacement 显示文摘 | NUROZLER F TOKGOZOGLU L PASAOGLU I | 1996 | J Card Surg1996，11，6： | 1 |
| 11 | Comparison of World Health Organization 2000/2004 and World Health Organization 2010 classifications for gastrointestinal and pancreatic neuroendo- crine tumors显示文摘 | Pasaoglu E Dursun N Ozyalvacli G | 2015 | Ann Diagn Pathol2015，19，2： | 1 |
| 12 | Poten- tial vehicle fleet CO2 reductions and cost implications for various vehicle technology deployment scenarios in Europe显示文摘 | PASAOGLU G HONSELAAR M THIEL C | 2012 | Energy Policy2012，40，1： | 1 |
| 13 | Devega's Tricuspidannuloplasty: analysis of 195 patients 显示文摘 | Pasaoglu I Demicrin M Dogan R | 1990 | Thorac Cardiaovascular Surgery1990，38，6： | 1 |
| 14 | Somatosensory and auditory brain stem conduction after head injury:a comparison with clinical features in prediction of outcome显示文摘 | Lindsay K Pasaoglu A Hirst D | 1990 | Neurosurgery1990，26，2： | 1 |
| 15 | Change in the circulation endothelin and atrial natriuretic peptide levels during coronary artery bypass surgery显示文摘 | Pasaoglu L Erbas B Varoglu E | 1993 | Japan Heart J1993，34，： | 1 |
| 16 | Surgical management of craniocerebral gunshot wounds显示文摘 | Pasaoglu A Gok AV | 1992 | Neurosurg Rev1992，15，1： | 1 |
| 17 | Role of ghrelin and leptin in predicting the severity of acute pancreatitis显示文摘 | Kerem M Bedifli A Pasaoglu H | 2007 | Dig Dis Sci2007，52，4： | 1 |
| 18 | Clinical analysis and Results of operative treatment of 41 brain abscesses 显示文摘 | Yildizhan A Pasaoglu A Ozkul MH | 1991 | Neurosurg Rev1991，14，： | 1 |
| 19 | Endogenous neuropeptides in patients with acute traumatic head injury, I: Cerebrospinal fluid beta-endorphin levels are increased with in 24 hours following the trauma显示文摘 | Pasaoglu H InciKE Kurtsoy A | 1996 | Neuropeptides1996，30，1： | 1 |
| 20 | Clinical analysis and results of operative treatment of 41 brain abscesses显示文摘 | Yildizhan A Pasaoglu A Ozkul MH | 1991 | Neurosurgery Rev1991，14，： | 1 |
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