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| 1 | Cardiotrophin 1 stimulates beneficial myogenic and vascular remodeling of the heart显示文摘出生后的心通过 hypertrophic 生长适应应力和超载,可能病理学或有益的一个过程(生理的肥大) 。生理的肥大改进心脏的性能在健康并且 diseased 个人,然而,宣传这有利改编的机制仍然保持糟糕定义。我们识别 cytokine cardiotrophin (CT1 ) 1 作为能够包括导致的导出 cardiomyocyte 的 angiogenic 信号的心肌层,和刺激的短暂、可逆的肥大概括心的生理的生长的特色的一个因素增加了由脉管形成。CT1 的能力从 caspase 激活的调停 CK2 的制止发源导致生理的肥大,阻止到无限制的病理学的生长的转变。外长的 CT1 蛋白质交货稀释了病理并且在正确的心失败的一个严格的模型恢复了可收缩的功能,建议为这难处理的心脏病的一种新奇处理选择。 | Mohammad Abdul-Ghani Colin Suen Baohua Jiang Yupu Deng Jonathan J Weldrick Charis Putinski Steve Brunette Pasan Femando Tom T Lee Peter Flynn Frans H H Leenen Patrick G Burgon Duncan J Stewar Lynn A Megeney | 2017 | Cell Research2017，27，10： | 8 |
| 2 | Dinuclear and twoand three-dimensional gadolinium(Ⅲ) complexes with mono-and dicarboxylate ligands:synthesis,structure and magnetic properties显示文摘 | Canadillas-Delgado L Fabelo O Cano J Pasan J Delgado F S Lloret F Julve M Ruiz-Perez C | | 0，，10： | 1 |
| 3 | Clinical trials with pseudomonas exotoxin immunotoxins显示文摘 | Pai LH Pasan I | 1998 | Curt Top Mierobiol Immunol1998，234，： | 1 |
| 4 | Structural versatility of the malonate ligand as a tool for crystal engineering in the design of molecular magnets显示文摘 | Rodriguez-Martin Y Hemandez-Molina M Delgado F S Pasan J Ruiz-Perez C Sanchiz J Lloret F Julve M | | 0，，87： | 1 |
| 5 | Dialysis therapy显示文摘 | BAILEY J | 1998 | N Engl J Med1998，338，： | 1 |
| 6 | Novel cobalt( II ) coordination poly- mers based on 1,2,4,5-benzenetetracarboxylic acid and extended bis-mortodentate ligands 显示文摘 | FABELO O PASAN J CAlqIADILLAS-DELGA- DO L | 2009 | Cryst Eng Comm2009，11，： | 1 |
| 7 | Hypoxia and oxidative stress:The role of the anaerobic gut,the hepatic arterial buffer response and other defence mechanisms of the liver显示文摘The liver is considered a vital organ and is the hub for multiple chemical functions,such as intermediary metabolism and the detoxification of ingested toxins,which are essential for the preservation of life,hence,the origin or the word“liver”.The liver has enormous,highly diversified catalytic potential.This enormous catalytic potential generates massive oxidative stress,which is important for the functions of the liver but is detrimental to the viability of the liver.The liver receives approximately 80%of its blood supply from the portal vein,which brings less saturated blood from the gastrointestinal tract.Hepatocytes operate in a relatively hypoxic microenvironment due to this portal inflow.The development of this hypoxic microenvironment of the liver is an important evolutionary adaptation for its detoxification function that is not recognized in the literature as a defence mechanism against the oxidative stress generated during the detoxification process.This review describes liver function in relation to its oxidative catalytic potential and the oxidative stress generated by it as well as the evolutionary defence mechanisms present in the liver against this oxidative stress to provide new insights into liver function. | Samapriya Pasan Hewawasam | 2020 | World Journal of Meta-Analysis2020，8，2： | 0 |
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