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	题名	作者	年代	出处	被引量
1	Overexpression of Slug is associated with malignant progression of esophageal adenocarcinoma显示文摘AIM: To characterise expression of known E-cadherin repressors; Snail, Slug and Twist in the development of esophageal adenocarcinoma. METHODS: E-cadherin, Slug, Snail and Twist mRNA expression in Barrett's metaplasia and esophageal adenocarcinoma specimens was examined by real-time reverse transcription-polymerase chain reaction (RT-PCR). Semi-quantitative immunohistochemistry was used to examine cellular localisation and protein levels. The effect of Slug on epithelial mesenchymal transition (EMT) markers was examined by transfection of Slug into an adenocarcinoma line OE33.RESULTS: Cellular localisation of Slug in Barrett's metaplasia was largely cytoplasmic whilst in adenocarcinoma it was nuclear. Semi-quantitative analysis indicated that Slug was more abundant in adenocarcinoma compared to matched Barrett's metaplastic specimens. Snail and Twist were expressed in adenocarcinoma but were cytoplasmic in location and not induced compared to Barrett's mucosa. These observations were supported by mRNA studies where only Slug mRNA was shown to be over-expressed in adenocarcinoma and inversely correlated to E-cadherin expression. Overexpression of Slug in OE33 mediated E-cadherin repression and induced the mesenchymal markers vimentin and fibronectin.CONCLUSION: Progression to adenocarcinoma is associated with increased Slug expression and this may represent a mechanism of E-cadherin silencing.	Paras Jethwa Mushal Naqvi Robert G Hardy Neil A Hotchin Sally Roberts Robert Spychal Chris Tselepis	2008	World Journal of Gastroenterology2008，14，7：	24
2	Converting ceria polyhedral nanoparticles into single-crystal nanospheres 显示文摘	Feng X D Sayle D C Wang Z L Paras M S Santora B Sutorik A C Sayle T X T Yang Y Ding Y Wang X D Her Y S	2006	Science2006，312，5779：	1
3	PRR3 Is a vascular regulator of TOCI stability in the Arabidopsis circadian clock 显示文摘	PARA A FARRE E M IMAIZUMI T	2007	Plant Cell2007，19，11：	1
4	Risk factors of prolonged mechanicalventilation following open heart surgery:what has changed overthe last decade? 显示文摘	Siddiqui MM Paras I Jalal A	2012	Cardiovascular Diagnosis and Therapy2012，2，3：	1
5	Effect of liquid properties on the performance of bubble column reactors with fine pore spargers 显示文摘	MOUZA A A DALAKOGLOU G K PARAS S V	2005	Chem Eng Sci2005，60，：	1
6	Visual observa-tions of flooding in narrow rectangular channels 显示文摘	Vlachos N A Paras S V Monza A A	2001	Interna-tional Journal of Multiphase Flow2001，27，14：	1
7	Falling film andflooding phenomena in small diameter vertical tubes : Theinfluence of liquid properties 显示文摘	Mouza A A Pantzali M N Paras S V	2005	Chemical EngineeringScience2005，60，18：	1
8	Characteristics of developing free failing films at intermediate Reynolds and high Kapitza num- bers 显示文摘	DROSOS E I P PARAS S V KARABELAS A J	2004	International Journal of Multiphase Flow2004，30，：	1
9	A reinvestigation of the structure of biruloquinone, a 9,10-phenanthrenequinone isola- ted from Mycosphaerella rubella 显示文摘	Armone A Nasini G de Para OV	1991	Phytochemistry1991，31，：	1
10	LDA Measurements of Local Velocities Inside the Gas Phase in Horizontal Stratified/Atomization Two-phase Flow 显示文摘	Paras S V Vlachos N A Karabelas A J	1998	Int J Multiphase Flow1998，24，4：	1
11	A functional genomics approach reveals CHE as a component of the Arabidopsis circadian clock 显示文摘	PRUNEDA-PAZ J L BRETON G PARA A	2009	Science2009，323，5920：	1
12	Structural and molecular properties of dialdehyde starch显示文摘	Fiedorowicz M Para A	2006	Carbohydrate Polymers2006，63，3：	1
13	Bioconcentration factor estimates of polycyclic aromatic hydrocarbons in grains of corn plants cultivated in soils treated with sewage sludge显示文摘	PARAíBA L C QUEIROZ S C N MAIA A H N	2010	Science of the Total Environment2010，408，16：	1
14	C'ounter-current gas-liquid flow in a vertical narrow channel : Liquid film character-istics and flooding phenomena 显示文摘	Drosos E Paras S V Karabelas A J	2006	International Journal ofMultiphase Flow2006，32，1：	1
15	Graphene-aluminum nanocomposites显示文摘	Bartolucci S F Paras J Rafiee M A	2011	Materials Science and Engineering:A2011，528，27：	1
16	Structural and molecular properties of dialdehyde starch显示文摘	Fiedorowicz M Para A	2006	Carbohydr Polym2006，63，：	1
17	Pricing and Hedging Derivative Securities in Markets with Uncertain Volati显示文摘	Ave\|Ianeda M Levy A Paras A	1995	App Math Finance1995，2，2：	1
18	Converting ceria polyhedral nanoparticles into single-crystal nanospheres显示文摘	FENG Xiang-dong SAYLE D C WANG Zhong-lin PARAS M S SANTORA B SUTORIK A C SAYLE T X T YANG Yi DING Yong WANG Xu-dong HER Y S	2006	Science2006，312，：	1
19	Countercurrent gas-liquid flow in a vertical narrow channel-liquid film characteristics and flooding phenomena显示文摘	DROSOS E PARAS S V KARABELAS A J	2006	International Journal of Multiphase Flow2006，32，1：	1
20	Experimental study of bubble formation at metal porous spargers:Effect of liquid properties and sparger characteristics on the initial bubble size distribution 显示文摘	Kazakis N A Mouza A A Paras S V	2008	Chemical Engineering Science2008，137，：	1

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