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| 1 | What will the future hold for artificial organs in the service of assisted reproduction: prospects and considerations显示文摘Assisted reproduction provides a wide spectrum of treatments and strategies addressing infertility.However,distinct groups of infertile patients with unexplained infertility,congenital disorders,and other complex cases pose a challenge in in vitro fertilization(IVF)practices.This special cohort of patients is associated with futile attempts,IVF overuse,and dead ends in management.Cutting edge research on animal models introduced this concept,along with the development of artificial organs with the aim to mimic the respective physiological functions in reproduction.Extrapolation on clinical application leads to the future use of infertility management in humans.To date,the successful clinical application of artificial reproductive organs in humans is not feasible because further animal model studies are required prior to clinical trials.The application of these artificial organs could provide a solution to infertility cases with no other options.This manuscript presents an overview on the current status,future prospects,and considerations on the potential clinical application of artificial ovary,uterus,and gametes in humans.This paper presents how the IVF practice landscape may be shaped and challenged in the future,along with the subsequent concerns in assisted reproductive treatments. | Mara Simopoulou Konstantinos Sfakianoudis Petroula Tsioulou Anna Rapani Polina Giannelou Nikolaos Kiriakopoulos Agni Pantou Nikolaos Vlahos George Anifandis Stamatis Bolaris Konstantinos Pantos Michael Koutsilieri | 2019 | Frontiers of Medicine2019，13，6： | 2 |
| 2 | Time-dependent changes in the expression of thyroid hormone receptor alpha 1 in the myocardium after acute myocardial infarction: possible implications in cardiac remodelling显示文摘 | Pantos C Mourouzis I Xinaris C | 2007 | Eur J Endocrinol2007，156，4： | 1 |
| 3 | Thyroid hormone and phenotypes of cardioprotection显示文摘 | Pantos C Malliopoulou V Varonos DD | 2004 | Basic Res Cardiol2004，99，2： | 1 |
| 4 | Experimental study of void formation in eutectic and lead-free solder bumps of flip-chip assemblies 显示文摘 | Wang D J Panto R L | 2006 | Journal of Electronic Packaging2006，128，： | 1 |
| 5 | Thyroid hormone improves postischaemic recovery of function while limiting apoptosis: a new therapeutic approach to support hemodynamics in the setting of ischaemia-reperfusion?显示文摘 | PANTOS C MOUROUZIS I SARANTEAS T | 2009 | Basic Res Cardiol2009，104，： | 1 |
| 6 | Fine Tuning the Anion Binding Properties of 2,6-Diamidopyridine Dipyrromethane Hybrid Macrocycle 显示文摘 | Seller J L Katayev E Pantos G D | 2005 | J Am Chem Soc2005，127，11： | 1 |
| 7 | Hyperthyroid hearts display a phenotype of cardioprotection against ischemic stress:a possible involvemant of heat shock protein 70 显示文摘 | Pantos C Malliopoulou V Mourouzis I | 2006 | Horm Metab Res2006，38，5： | 1 |
| 8 | Thyroid hormone receptors alpha1 and beta1 are downregulated in the post-infarcted rat heart:consequences on the response to ischaemia-reperfusion显示文摘 | Pantos C Mourouzis I Saranteas T | 2005 | Basic Res Cardiol2005，100，6： | 1 |
| 9 | A novel strategy for variable-speed wind turbines' participation in primary frequency control显示文摘 | Zertek A Verbic G Pantos M | 2012 | IEEE Transactions on Sustainable Energy2012，3，4： | 1 |
| 10 | Rebuilding the post-infarcted myocardium by activating 'physiologic' hypertrophic signaling pathways:the thyroid hormone paradigm,Heart Failure Reviews显示文摘 | Pantos C Mourouzis I Cokkinos DV | 2008 | Heart Fail Rev2008，，： | 1 |
| 11 | Optimised Control Approach for Frequency Control Contribution of Variable Speed Wind Turbines显示文摘 | ZERTEK A VERBIC G PANTOS M | 2012 | IET Renewable Power Generation2012，6，1： | 1 |
| 12 | Thyroid hormone attenuates cardiac remodeling and improves hemodynamics early after acute myocardial infarction in rats显示文摘 | Pantos C Mourouzis I Markakis K | 2007 | Eur J Cardiothorac Surg2007，32，2： | 1 |
| 13 | Enhanced tolerance of the rat myocardium to ischemia and reperfusion injury early after acute myocardial infarction显示文摘 | Pantos C Mourouzis I Dimopoulos A | 2007 | Basic Res Cardiol2007，102，4： | 1 |
| 14 | Long-term thyroxine administration protects the heart in a pattern similar to ischemic preconditioning 显示文摘 | Pantos CI Malliopoulou VA Mourouzis IS | 2002 | Thyroid2002，12，4： | 1 |
| 15 | Thyroid hormone receptors alphal and betal are downregulated in the post- infarcted rat heart~ consequences on the response to ischaemia-reperfusion显示文摘 | Pantos C Mourouzis I Saranteas T | 2005 | Basic Res Cardiol2005，100，5： | 1 |
| 16 | Time- dependent changes in the expression of thyroid hormone receptor alpha 1 in the myocardium after acute myocardial infarction: Possible implications in cardiac remodeling显示文摘 | Pantos C Mourouzis I Xinaris C | 2007 | Eur J Endocrinol2007，156，4： | 1 |
| 17 | Thyroid hormone is a critical determinant of myocardial performance in patients with heart failure: potential therapeutic implications显示文摘 | PANTOS C DRITSAS A MOUROUZIS I | 2007 | Eur J Endocrinol2007，157，4： | 1 |
| 18 | TNF-α Administration in Neonatal Cardiomyocytes is Associated with Differential Expression of Thyroid Hormone Receptors: A Response Prevented by T3显示文摘 | C. Pantos C. Xinaris I. Mourouzis A. Kokkinos D. Cokkinos | 2008 | Horm Metab Res2008，，10： | 1 |
| 19 | Myocardial protection in man-from re- search concept to clinical practice 显示文摘 | Cokkinos D V Pantos C | 2007 | Heart Fail Rev2007，12，34： | 1 |
| 20 | Flow patterns at stented coronary bifurcations: computational fluid dynamics analysis 显示文摘 | KATRITSIS DG THEODORAKAKOS A PANTOS I | 2012 | Circul Cardiovasc Interv2012，5，4： | 1 |
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