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| 1 | The role of DJ-1 in the oxidative stress cell death cascade after stroke显示文摘Oxidative stress is closely associated with secondary cell death in many disorders of the central nervous system including stroke,Parkinson’s disease,Alzheimer’s disease.Among many aberrant oxidative stress-associated proteins,DJ-1 has been associated with the oxidative stress cell death cascade primarily in Parkinson’s disease.Although principally expressed in the cytoplasm and nucleus,DJ-1 can be secreted into the serum under pathological condition.Recently,a close pathological association between DJ-1 and oxidative stress in stroke has been implicated.To this end,we and others have demonstrated the important role of mitochondria in neuroprotection for stroke by demonstrating that the translocation of DJ-1 in the mitochondria could potentially mitigate mitochondrial injury.Here,we discuss our recent findings testing the hypothesis that DJ-1 not only functions as a form of intracellular protection from oxidative stress,but that it also utilizes paracrine and/or autocrine cues in order to accomplish extracellular signaling between neighboring neuronal cells,resulting in neuroprotection.This article highlights recent evidence supporting the status of DJ-1 as key anti-oxidative stress therapeutic target for stroke. | Paolina Pantcheva Maya Elias Kelsey Duncan Cesar V.Borlongan Naoki Tajiri Yuji Kaneko | 2014 | Neural Regeneration Research2014，9，15： | 5 |
| 2 | Drug-and cell-based therapies for targeting neuroinflammation in traumatic brain injury显示文摘TBI pathology:Traumatic brain injury(TBI)is caused by an external force to the head,resulting in trauma to the brain.Approximately 1.7 million Americans suffer from TBI every year.Out of the 1.7 million suffering from TBI,an estimated52,000 injuries result in death,leaving a mass amount of people with symptoms that could last a few days,a few years,or their entire life(Faul et al.,2010).TBI can be classified as mild,moderate and severe.Depending on the classification and | Sussannah Kaelber Paolina Pantcheva Cesar V.Borlongan | 2016 | Neural Regeneration Research2016，11，10： | 3 |
| 3 | Limit Theorems for Extreme Order Statistics Under Nonlinear Normalization 显示文摘 | Pantcheva E I | 1985 | Lecture Notes in Math1985，1155，： | 1 |
| 4 | Comparison of acute structural and histopathological changes of the porcine ciliary processes after endoscopic cyclophotocoagulation and transscleral cyclophotocoagulation显示文摘 | Pantcheva MB Kahook MY Schuman JS | 2007 | Clin Experiment Ophthalmol2007，35，3： | 1 |
| 5 | Comparison of acute structural and histopathological changes in human autopsy eyes after endoscopic cyclophotocoagulation and trans-scleral cyclophotocoagulation显示文摘 | Pantcheva MB Kahook MY Schuman JS | 2007 | Br J Ophthalmol2007，91，2： | 1 |
| 6 | Activation of caspase 9 in a rat model of experimental glaucoma显示文摘 | Hanninen VA Pantcheva MB Freeman EE | 2002 | Curr Eye Res2002，25，6： | 1 |
| 7 | Activation of caspase 9 in a rat model of experimental glaucoma 显示文摘 | Hanninen V A Pantcheva M B Freeman E E | 2002 | Curr Eye Res2002，25，6： | 1 |
| 8 | Comparison of acute structural and histopathological changes of the porcine ciliary processes after endoscopic cyclophotocoagulation and transscleral cyclophotocoagulation 显示文摘 | Pantcheva MB Kahook MY Schuman JS | 2007 | Clin Exp Ophthalmol2007，35，3： | 1 |
| 9 | Caspase activation in an experimental model of retinal detachment显示文摘 | Zacks DN Hanninen V Pantcheva M Ezra E Grosskreutz C Miller JW | 2003 | Invest Ophthalmol Vis Sci2003，44，3： | 1 |
| 10 | Tafluprost:a novel prostaglandin analog for treatment of glaucoma显示文摘 | Pantcheva MB Seibold LK Awadallah NS | | 0，，： | 1 |
| 11 | Comparison of acute structural and histopathological changes in human autopsy eyes after endoscopic cyclophotocoagulation and trans-scleral cyclo- photocoagulation 显示文摘 | Pantcheva MB Kahook MY Schuman J S | 2007 | Br J Ophthalmol2007，91，： | 1 |
| 12 | Activation of caspase 9 in a rat model of experimental glaucoma显示文摘 | Hanninen VA Pantcheva MB Freeman EE Poulin NR Grosskreutz CL | 2002 | Curt Eye Res2002，25，6： | 1 |
| 13 | Caspase activation in an experimental model of retinal detachment显示文摘 | Zacks DN Hanninen V Pantcheva M Ezra E Grosskreutz C Miller JW | 2003 | Invest Ophthalmol Vis Sci2003，44，3： | 1 |
| 14 | FKS06 blocks activation of the intrinsic caspase cascade after optic nerve crush 显示文摘 | Grosskreutz CL Hfinninen VA Pantcheva MB Huang W Poulin NR Dobberfuhl AP | 2005 | Exp Eye Res2005，80，5： | 1 |
| 15 | Ab Interno Trabeculectomy 显示文摘 | Pantcheva MB Kahook MY | 2010 | Middle East Afr J Ophthalmol2010，17，： | 1 |
| 16 | Corneal thickness and in- traocular pressure in edematous corneas before and after Descemet stripping with automated endothelial keratoplasty 显示文摘 | Chang D T Pantcheva M B Noecker R J | 2010 | Cornea2010，29，10： | 1 |
| 17 | The syntactic structure of Locations, Goals, and Sources显示文摘 | Marina Pantcheva | 2010 | Linguistics2010，，5： | 1 |
| 18 | Com- parison of acute structural and histopathological changes in hum an autopsy eyes after endoscopic cyclophotocoagulation and trans - seleral eyclophotocoagulation 显示文摘 | PANTCHEVA M B KAHOOK M Y SCHUMAN J S | 2007 | Br J Ophthalmol2007，91，2： | 1 |
| 19 | Com- parison of acute structural and histopatholagical changes of the por- cine ciliary processes after endoscopic cyclophotocoagulation and transscleral cyclophotocoagulation 显示文摘 | PANTCHEVA M B KAHOOK M Y SCHUMAN J S | 2007 | Clin Exp Ophthalmol2007，35，3： | 1 |
| 20 | Limit Theorems for Extreme Order Statistics Under Nonlinear Normalization 显示文摘 | PANTCHEVA E I | 1985 | Lecture Notes in Mathematics1985，1155，： | 1 |
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