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| 1 | Pyogenic liver abscess:An audit of 10 years’experience显示文摘AIM:To describe our own experience with pyogenic liver abscesses over the past 10 years and investigate the risk factors associated with failure of initial percutaneous therapy.METHODS:A retrospective study of records of 63 PLA patients presenting between 1998 and 2008 to Australian tertiary referral centre,were reviewed.Amoebic and hydatid abscesses were excluded.Demographic,clinical,radiological,and microbiological characteristics,as well as surgical/radiological interventions,were recorded.RESULTS:Sixty-three patients(42 males,21 females) aged 65(±14) years[mean±(SD) ]had prodromal symptoms for a median(interquartile range;IQR) of 7(5-14) d.Only 59%of patients were febrile at presentation;however,the serum C-reactive protein was elevated in all 47 in whom it was measured.Liver function tests were non-specifically abnormal.67%of patients had a solitary abscess,while 32%had>3 abscesses with a median(IQR) diameter of 6.3(4-9) cm.Causative organisms were:Streptococcus milleri 25%,Klebsiella pneumoniae 21%,and Escherichia coli 16%.A presumptive cryptogenic cause was most common (34%).Four patients died in this series:one from sepsis,two from advanced cancer,and one from acute myocardial infarction.The initial procedure was radiological aspiration±drainage in 54 and surgery in two patients.17%underwent surgical management during their hospitalization.Serum hypoalbuminaemia[mean (95%CI) :32(29-35) g/L vs 28(25-31) g/L,P=0.045] on presentation was found to be the only factor related to failure of initial percutaneous therapy on univariate analysis.CONCLUSION:PLA is a diagnostic challenge,because the presentation of this condition is non-specific.Intravenous antibiotics and radiological drainage in the first instance allows resolution of most PLAs;However,a small proportion of patients still require surgical drainage. | Tony CY Pang Thomas Fung Jaswinder Samra Thomas J Hugh Ross C Smith | 2011 | World Journal of Gastroenterology2011，17，12： | 46 |
| 2 | DNA damage induced by chronic inflammation contributes to colon carcinogenesis in mice显示文摘 | Meira Lisiane B Bugni James M Green Stephanie L Lee Chung-Wei Pang Bo Borenshtein Diana Rickman Barry H Rogers Arlin B Moroski-Erkul Catherine A McFaline Jose L Schauer David B Dedon Peter C Fox James G Samson Leona D | 2008 | Journal of Clinical Investigation2008，，7： | 2 |
| 3 | Genetic transformation of wheat mediated by Agrobacterium tumefaciens显示文摘 | Cheng M Fry J E Pang S Zhou H Hironaka C M Duncan D R Conner T W Wan Y | 1997 | Plant Physiol1997，，： | 2 |
| 4 | Origin and therapy for hypertriglyceridaemia in type 2 diabetes显示文摘Hypertriglyceridaemia(HTG) is a risk factor for cardiovascular disease(CVD) in type 2 diabetes and is caused by the interaction of genes and non-genetic factors, specifically poor glycaemic control and obesity. In spite of statin treatment, residual risk of CVD remains high in type 2 diabetes, and this may relate to HTG and atherogenic dyslipidemia. Treatment of HTG emphasises correcting secondary factors and adverse lifestyles, in particular, diet and exercise. Pharmacotherapy is also required in most type 2 diabetic patients. Statins are the first-line therapy to achieve recommended therapeutic targets of plasma low-density lipoprotein cholesterol and non-high-density lipoprotein cholesterol. Fibrates, ezetimibe and n-3 fatty acids are adjunctive treatment options for residual and persistent HTG. Evidence for the use of niacin has been challenged by non-significant CVD outcomes in two recent large clinical trials. Further investigation is required to clarify the use of incretin-based therapies for HTG in type 2 diabetes. Extreme HTG, with risk of pancreatitis, may require insulin infusion therapy or apheresis.New therapies targeting HTG in diabetes need to be tested in clinical endpoint trials. The purpose of this review is to examine the current evidence and provide practical guidance on the management of HTG in type 2 diabetes. | Jing Pang Dick C Chan Gerald F Watts | 2014 | World Journal of Diabetes2014，5，2： | 2 |
| 5 | Chemical reactions on rutile TiO2(110)显示文摘 | Lun Pang C Lindsay R Thomton G | 2008 | Chem Soc Rev2008，37，10： | 1 |
| 6 | Fabric defect detection by Fourier analysis 显示文摘 | Chan C H Pang G K H | 2000 | IEEE Transactions on Industry Applications2000，36，5： | 1 |
| 7 | Impact of monsoonal climatic change on Holocene overbank flooding along Sushui River, middle reach of the Yellow River, China 显示文摘 | Huang C C Pang J L Zha X C | 2007 | Quaternary Science Reviews2007，26，： | 1 |
| 8 | Phosphorus fractions and phosphate sorption characteristics in relation to the sediment compositions of shallow lakes in the middle and lower reaches of Yangtze River region, China 显示文摘 | Wang S G Jin X C Pang Y | 2005 | Journal of Colloid and Interface Science2005，289，2： | 1 |
| 9 | Effects of heating rate and ion-exchangeable cations on the pyrolysis yields from a Victorian brown coal显示文摘 | SATHE C PANG Y LI C-Z | 1999 | Energy Fuels1999，13，3： | 1 |
| 10 | Strategic gaming analysis for electric power systems:an MPEC approach显示文摘 | Hobbs B F Metzler C B Pang J S | 2000 | IEEE Transactions on Power Systems2000，15，2： | 1 |
| 11 | An improved formalism for FDTD analysis of thin-slot problems by conformal mapping technique显示文摘 | Wu C T Pang Y H Wu R B | 2003 | IEEE Trans Antennas Propagation2003，51，9： | 1 |
| 12 | The effect of electric field, annealing temperature and filler loading on the percolation threshold of polystyrene containing carbon nanotubes and graphene nanosheets 显示文摘 | Pang H Chen C Zhang Y C Ren P G Yan D X Li Z M | 2011 | Carbon2011，49，6： | 1 |
| 13 | Behavior of reinforced concrete membrane elements in shear显示文摘 | Pang X B Hsu T T C | 1995 | ACI Structural Journal1995，92，6： | 1 |
| 14 | CD27 is a thymic determinant of the balance between interferon-γ- and interleukin-17-producing γδ T cell subsets显示文摘 | Ribot J C deBarros A Pang D J | 2009 | Nat Immunol2009，10，： | 1 |
| 15 | Molecular analysis of PinX1 in medulloblastomas显示文摘 | Chang Q Pang J C Li J | 2004 | Int J Cancer2004，109，2： | 1 |
| 16 | Engineering and economic applications of complementarity problems显示文摘 | Ferris M C Pang J S | 1997 | Siam Review1997，39，4： | 1 |
| 17 | De novo sequencing and transcriptome analysis of the desert shrub, Ammopiptanthus mongolicus, during cold acclimation using Illumina/Solexa 显示文摘 | PANG T YE C Y XIA X L | 2013 | BMC Genomics2013，14，： | 1 |
| 18 | Solution and Stability of a General Mixed Typecubic and Quartic Functional Equation显示文摘 | ZHAO X YANG X PANG C | 2013 | J Funct Spaces and Appl2013，，67： | 1 |
| 19 | Chcnlical and cnzym~ltic translbmaations of nimesulide to GSH conjugates through reductive and oxidative mechanisms显示文摘 | Zhou L Pang X Xie C el al | 2015 | Chem Res Toxicol2015，28，12： | 1 |
| 20 | Effect of duloxetine on pain,function,and quality of life among patients with chemotherapy-induced painful peripheral neuropathy:a randomized clinical trial显示文摘 | Smith E M Pang H Cirrincione C | 2013 | JAMA2013，309，13： | 1 |
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