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| 1 | Efficacy and safety of standard and anti-reflux self-expanding metal stent: A systematic review and meta-analysis of randomized controlled trials显示文摘BACKGROUND Self-expanding metal stents are the main palliative treatment modality for unresectable esophageal cancer. Gastroesophageal reflux is a common adverse outcome after placement of esophageal stent for cancer involving the gastroesophageal junction and the gastric cardia. Anti-reflux stents with valve have been designed to prevent the acid reflux. The superiority of anti-reflux stent over standard stent in preventing gastroesophageal reflux has not been established well. This study compares the anti-reflux stent and the standard stent in terms of their efficacy to prevent acid reflux.AIM To compare the standard and the anti-reflux stents in terms of their efficacy,safety, and complications.METHODS The meta-analysis included 8 randomized clinical trials(RCTs) to compare pooled outcomes of total 395 patients. Primary outcomes include improvement in reflux symptoms and dysphagia score. Secondary outcomes include complications of stent migration, occlusion, and bleeding.RESULTS A total of eight RCTs were included in the meta-analysis. Compared to the standard stent, the anti-reflux stent showed a trend towards reduction in the dysphagia score without reaching a statistical significance [Standardized mean difference(SMD):-0.33(-0.71, 0.05); P = 0.09, I2: 37%]. There was no statistical difference in the gastrointestinal reflux(GER) scores between the two types of stents [SMD:-0.17(-0.78, 0.45); P = 0.008, I2: 74%]. Compared to standard stent,anti-reflux stent showed no difference in the risk of stent migration [OR: 1.37(0.66, 2.83); P = 0.40, I2: 0 %], bleeding [OR: 1.43(0.40, 5.13); P = 0.59, I2: 0 %], and obstruction [OR: 1.66(0.60, 4.60); P = 0.33, I2: 0 %].CONCLUSION Traditional self-expanding standard esophageal stent and anti-reflux stent with valve are similar in terms of outcomes and complications. | Sudha Pandit Hrishikesh Samant James Morris Steven J Alexander | 2019 | World Journal of Gastrointestinal Endoscopy2019，11，4： | 2 |
| 2 | Diphtheria toxoid loaded poly-(ε-caprolactone) nanoparticles as mucosal vaccine delivery systems显示文摘 | Singh J Pandit S Bramwell VW | 2006 | Methods2006，38，： | 1 |
| 3 | Neisseria gonorrhoeae porin modifies the oxidative burst of human professional phagocytes显示文摘 | Lorenzen DR Gunther D Pandit J | 2000 | Infect Immun2000，68，11： | 1 |
| 4 | Survival data from a phase II, open- label study of pazopanib or lapatinib monotherapy in patients with advanced and recurrent cervical cancer 显示文摘 | Monk B J Pandite LN | 2011 | J Clin Oncol2011，29，36： | 1 |
| 5 | Study of Geldart's Group A behaviour using the discrete element method simulation 显示文摘 | Pandit J K Wang X S Rhodes M J | 2005 | Powder Technology2005，160，1： | 1 |
| 6 | Post-traumatic epilep- sy:an overview显示文摘 | Agrawal A Timothy J Pandit L | 2006 | Clin Neurol Neuroaurg2006，108，5： | 1 |
| 7 | Diphtheria toxoid loaded poly-(epsilon-caprolactone) nanoparticles as mucosal vaccine delivery systems显示文摘 | Singh J Pandit S Bramwell VW | 2006 | Methods2006，38，2： | 1 |
| 8 | Mecha- nism for the allosteric regulation of phosphodiester- ase 2A deduced from the X-ray structure of a near full-length construct显示文摘 | Pandit J Forman MD Fennell KF | 2009 | PNAS2009，106，43： | 1 |
| 9 | Design and a- nalysis of a novel mechanical loading machine for dynamic in vivo axial loading显示文摘 | MACIONE J NESBITT S PANDIT V | 2012 | Review of scientific instruments2012，83，2： | 1 |
| 10 | Using mean duration and variation of procedure times to plan a list of surgical operations to fit into the scheduled list time显示文摘 | Pandit J J Tavare A | 2011 | Eur J Anaesthesiol2011，28，7： | 1 |
| 11 | Gas hold-up behavior of mechaniaclly agitated gas- liquid reactors using pitched blade downflow turbines显示文摘 | Rewatkar V B Deshpande A J Pandit A B | 1993 | Can J Chem Eng1993，，： | 1 |
| 12 | Hydrolysis of fatty oils-effect of cavitation 显示文摘 | Pandit A B Joshi J B | 1993 | Chemical Engineering Science1993，48，19： | 1 |
| 13 | Neisseria gonorrhoeae porin modifies the oxidative burst of human professional phagocytes 显示文摘 | Lorenzen D Gunther D Pandit J | 2000 | Infect Immun2000，68，11： | 1 |
| 14 | Crystal structure of human squalene synthasc - A key enzyme in cholesterol biosynthesis显示文摘 | Pandit J Danley DE Schuhe GK | 2000 | J Biol Chem2000，275，30： | 1 |
| 15 | Profibrotic role of miR-154 in pulmonary fibrosis 显示文摘 | Milosevic J Pandit K Magister M | 2012 | Am J Respir Cell Mol Biol2012，47，6： | 1 |
| 16 | One-dimensional Schrodinger equation with an almost periodic potential 显示文摘 | Osflund S Pandit R Rand D Sehellnhuber H J Siggia E D | 1983 | Phys Rev Lett1983，50，： | 1 |
| 17 | Post trau- matic epilepsy: an overview显示文摘 | AGRAWAL A TIMOTHY J PANDIT L | 2006 | Clinical Neurology and Neuro surgery2006，108，5： | 1 |
| 18 | Capsular hyaluronic acid in Pasteurella multocida type A and its counterpart in type D显示文摘 | Pandit K K Smith J E | 1993 | Res Vet Sci1993，54，1： | 1 |
| 19 | Effect of cyclodextrins on the complexation and transdermal delivery of bupranolol through rat skin显示文摘 | Babu R J Pandit J K | 2004 | Int J Pharm2004，271，： | 1 |
| 20 | Superficial or deep cervical plexus block for earotid endartereetomy: a systematic review of complications显示文摘 | Pandit J J Satya-Krishna R Gration P | 2007 | Br J Anaesth2007，99，2： | 1 |
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