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| 1 | Effects of carob-bean gum thickened formulas on infants' reflux and tolerance indices显示文摘AIM: To examine the effect of carob-bean gum(CBG) thickened-formulas on reflux and tolerance indices in infants with gastro-esophageal reflux(GER). METHODS: Fifty-six eligible infants(1-6 mo old) were randomly allocated to receive for two weeks a formula with either 0.33 g/100 m L(Formula A) or 0.45 g/100 m L(Formula B) of cold soluble CBG galactomannans respectively, or a formula with 0.45 g/100 m L of hot soluble CBG galactomannans(Formula C). No control group receiving standard formula was included in the study. Data on the following indices were obtained both at baseline and follow-up from all study participants: 24 h esophageal p H monitoring indices, anthropometrical indices(i.e., body weight and length) and tolerance indices(i.e., frequency of colics; type and frequency ofdefecations). From the eligible infants, forty seven were included in an intention-to-treat analysis to examine the effects of the two-week trial on esophageal 24 h p H monitoring, growth and tolerance indices. Repeated Measures ANOVA was used to examine the research hypothesis.RESULTS: Regarding changes in 24 h p H monitoring indices, significant decreases from baseline to followup were observed in the 'Boix Ochoa Score'(i.e., an index of esophageal acid exposure), in the total number of visible refluxes and in all symptoms related indices due to acid reflux only for infants provided with Formula A, while no significant changes were observed for infants provided with Formulas B and C. In addition, the significant decreases observed in two symptoms related p H monitoring indices(i.e., 'Symptom index for reflux' and 'Percentage of all reflux') for infants provided with Formula A were also found to differentiate significantly compared to the changes observed in the other two groups(P = 0.048 and P = 0.014 respectively). Concerning changes in anthropometric indices, body weight significantly increased among infants provided with Formulas A and C, but not for infants provided with Formula B. As far as tolerance indices were concerned, the numbers of total and diarrheic defecations increased significantly only in infants provided with Formula B and these changes were significantly higher compared to the decreases observed in infants fed with Formulas A and C(P = 0.003 and P = 0.015 respectively. Lastly the number of colics significantly decreased in all infants, irrespective of the tested formula. CONCLUSION: Formula A(i.e., 0.33 g/100 m L of cold galactomannans) was effective in reducing certain p Hmonitoring indices of uncomplicated GER, increased body weight and was well-tolerated by infants. | Miglena Georgieva Yannis Manios Niya Rasheva Ruzha Pancheva Elena Dimitrova Anne Schaafsma | 2016 | World Journal of Clinical Pediatrics2016,5,1: | 2 |
| 2 | Effects of salicylic acid on growth and photosynthesis in barley plants 显示文摘 | PANCHEVA T V POPOVA L P UZUNOVA A N | 1996 | Journal of Plant Physiology1996,149,12: | 1 |
| 3 | Limit Theorems for Extreme Order Statistics Under Nonlinear Normatization 显示文摘 | PANCHEVA E | 1985 | Lecture Notes in Mathematics1985,,1155: | 1 |
| 4 | Heat shock and osmotically dependent steps by DNA uptake after Escherichia coli electroporation显示文摘 | Antonov PA Maxinova VA Pancheva RP | 1993 | Biochim Biophys Acta1993,1216,: | 1 |
| 5 | Electrochemically pre- pared and optimized membrane compositions for silver ( Ⅰ ) :Responsive chalcogenide-based ion-selective electrodes显示文摘 | Neshkova M T Pancheva E M | 1996 | Electroanal1996,8,6: | 1 |
| 6 | An explanation for the seasonal dependence of midlatitude sporadic E layer显示文摘 | Haldoupis C Pancheva D Singer W | | 0,,: | 1 |
| 7 | Design and synthesis of highly selective in vitro and in vivo uterine receptor antagonists of oxytocin: comparisons with Atosiban显示文摘 | Manning M Miteva K Pancheva S | 1995 | Int J Pept Protein Res1995,46,3: | 1 |
| 8 | Terdiurnal tidelike variability in sporadic E layers显示文摘 | Haldoupis C Pancheva D | | 0,,: | 1 |
| 9 | A study of tidal and planetary wave periodicities present in midlatitude sporadic E layers显示文摘 | Haldoupis C Pancheva D Mitchell N J | | 0,,: | 1 |
| 10 | An explana- tion for the seasonal dependence of midlatitude sporadic E layers 显示文摘 | Haldoupis C Pancheva D Singer W | 2007 | Journal of Geophysical Research2007,112,: | 1 |
| 11 | Neural correlates of lexicon grammar:,evidence from the production,reading,and judgment inflection in aphasia显示文摘 | Ullman MT Pancheva R Love T | 2005 | Brain Lang2005,93,: | 1 |
| 12 | Effect of salicylic acid on the synthesis of ribulose-1,5-bisphosphate carboxylase/oxygenase in barleyleaves 显示文摘 | PANCHEVA T V POPOV A L P | 1998 | Journal of Plant Physiology1998,152,45: | 1 |
| 13 | Effect of salicylic acid on growth and photosynthesis in barley plants 显示文摘 | PANCHEVA T V POPOV A L P UZUNOVA A M | 1996 | J ournalof Plant1996,149,12: | 1 |
| 14 | Evidence for nonlinear coupling of planetary wave and tides in the lower thermosphere over Bulgaria显示文摘 | PANCHEVA D | 2000 | J Atmos Solar-Terr Phys2000,62,2: | 1 |
| 15 | Effects of salicylic acid on growth and photosynthesis in barley plants 显示文摘 | Pancheva T V Popova L P Uzunova A N | 1996 | Journal of Plant Physiology1996,149,12: | 1 |
| 16 | Effects of salicylic acid on growth and photosynthesis in barley plants显示文摘 | Pancheva T V Popowa L P Uzunova A N | 1996 | Plant Physiol1996,,149: | 1 |
| 17 | Effects of salicylic acid on growth and photosynthesis in barley plants显示文摘 | Pancheva T V Popova L P Uzunova A N | 1996 | Joumal of Plant Physiology1996,149,: | 1 |
| 18 | Effects of salicylic acid on growth and photosynthesis in harley plants 显示文摘 | Pancheva T V Popowa L P Uzunova A N | 1996 | Journal of Plant Physiology1996,149,: | 1 |
| 19 | Effect of salicylic acid on growth and photosynthesis in barley plants显示文摘 | PANCHEVA T V POPOVA L P UZUNOVA A M | 1996 | Journal of Plant Physiology1996,149,: | 1 |
| 20 | Salicylic acid:properties,biosynthesis and physiological role 显示文摘 | Popova L Pancheva T Uzunova A | 1997 | Bulg J Plant Physiol1997,,23: | 1 |