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54篇 您的检索式:作者名="Pamula"
    题名 作者 年代 出处 被引量
1Sodium alendronate loaded poly(L-lactideco-glycolide)microparticles immobilized on ceramic scaffolds for local treatment of bone defects显示文摘Bone tissue regeneration in critical-size defects is possible after implantation of a 3D scaffold and can be additionally enhanced once the scaffold is enriched with drugs or other factors supporting bone remodelling and healing.Sodium alendronate(Aln),a widely used anti-osteoporosis drug,exhibits strong inhibitory effect on bone resorption performed by osteoclasts.Thus,we propose a new approach for the treatment of bone defects in craniofacial region combining biocompatible titanium dioxide scaffolds and poly(L-lactide-co-glycolide)microparticles(MPs)loaded with Aln.The MPs were effectively attached to the surface of the scaffolds’pore walls by human recombinant collagen.Drug release from the scaffolds was characterized by initial burst(2466% of the drug released within first 24 h)followed by a sustained release phase(on average 5 mg of Aln released per day from Day 3 to Day 18).In vitro tests evidenced that Aln at concentrations of 5 and 2.5 mg/ml was not cytotoxic for MG-63 osteoblast-like cells(viability between 8166% and 9863% of control),but it prevented RANKL-induced formation of osteoclast-like cells from macrophages derived from peripheral blood mononuclear cells,as shown by reduced fusion capability and decreased tartrateresistant acid phosphatase 5b activity(5665% reduction in comparison to control after 8 days of culture).Results show that it is feasible to design the scaffolds providing required doses of Aln inhibiting osteoclastogenesis,reducing osteoclast activity,but not affecting osteoblast functions,which may be beneficial in the treatment of critical-size bone tissue defects.Lucja Rumian Cornelia Wolf-Brandstetter Sina Roβler Katarzyna Reczynska Hanna Tiainen Havard J.Haugen Dieter Scharnweber Elzbieta Pamula 2020Regenerative Biomaterials2020,7,3:5
2Electrowetting-based droplet mixers for microfluidic systems 显示文摘Paik P Pamula V K Pollack M G 2003Lab on a Chip2003,3,1:1
3An Integrated Digital Microfluidic Lab-On-A-Chip for Clinical Diagnostics on Human Physiological Fluids显示文摘Srinivasan V Pamula V K Fair R B 2004Lab on a Chip2004,4,:1
4Bulk and surface chemical functionalities of type III PAN based carbon fibers显示文摘Pamula E Rouxhet G P 2003Carbon2003,41,10:1
5A680nA ECG acqui- sition IC for leadless pacemaker applications 显示文摘Long Y Harpe P Pamula V R 2014IEEE Transactions on Biomedical Circuits and Systems2014,8,6:1
6Electrowetting- Based Droplet Mixers for Microfluidic Systems 显示文摘Paik P Pamula V K Pollack M G 2003Lab Chip2003,3,1:1
7Nanoscale organization of adsorbed collagen: influence of substrate hydrophobicity and adsorption time 显示文摘PAMULA E DE CUPERE V M DUFRENE Y F 2004J Colloid Interface Sci2004,271,1:1
8An integrated digital mi-crofluidic lab-on-a-chip for clinical diagnostics on human physi-ological fluids 显示文摘Srinivasan V Pamula VK Fair RB 2004Lab Chip2004,4,4:1
9Rapid droplet mixers for digital mierofluidic systems显示文摘PAIK P PAMULA V K FAIR R B 2003Lab Chip2003,3,4:1
10Detailed Heat Transfer Measurements Inside Straight and Tapered Two-Pass Channels with Rib Turbulators显示文摘Srinath V Ekkad Gautam Pamula Manoj Shantiniketanam 2000Experimental Thermal and Fluid Science2000,22,34:1
11Polymorphisms in the KDR and POSTN Genes: Association with Breast Cancer Susceptibility and Prognosis显示文摘Asta F?rsti Qianren Jin Andrea Altieri Robert Johansson Kerstin Wagner Kerstin Enquist Ewa Grzybowska Jolanta Pamula Wioletta Pekala G?ran Hallmans Per Lenner Kari Hemminki 2007Breast Cancer Research and Treatment2007,,:1
12Vanoscale organization of adsorbed collagen: influence of substrate hydrophobicity and adsorption time 显示文摘Pamula E Cupere V D Dufrene Y F 2004Journal of Colloid and Interface Science2004,271,:1
13Nanostructured collagen layers obtained by adsorption and drying 显示文摘Jacquemart I Pamula E 2004Journal of Colloid and Interface Science2004,278,:1
14Bulk and surface chemical functionalities of type III PAN- based carbon fibres 显示文摘PAMULA E ROUXHET P G 2003Carbon2003,41,10:1
15Detailed Heat Transfer Measurements Inside Straight and Tapered Two-Pass Channels with Rib Turbulators显示文摘Srinath V Ekkad Gautam Pamula Manoj Shantiniketanam 2000Experimental Thermal and Fluid Science2000,22,:1
16Polymorphisms in the KDR and POSTN Genes: Association with Breast Cancer Susceptibility and Prognosis显示文摘Asta F?rsti Qianren Jin Andrea Altieri Robert Johansson Kerstin Wagner Kerstin Enquist Ewa Grzybowska Jolanta Pamula Wioletta Pekala G?ran Hallmans Per Lenner Kari Hemminki 2007Breast Cancer Research and Treatment2007,,1:1
17Bulk and surface chemicalfunctionalities of type III PAN-based carbon fibers显示文摘ELZBIETA Pamula PAUL G R 2003Carbon2003,41,10:1
18An integrated digital microfluidic lab-on-a-chip for clinical diagnostics on human physiological fluids显示文摘SRINIVASAN V PAMULA K FAIR B 2004Lab Chip2004,4,4:1
19Detailed Heat Transfer Measurements Inside Straight and Tapered Two-Pass Channels with Rib Turbulators显示文摘Srinath V Ekkad Gautam Pamula Manoj Shantiniketanam 2000Experimental Thermal and Fluid Science2000,22,:1
20Influence of crossflow- induced swirl and impingement on heat transfer in a two- pass channel connected by two rows of holes 显示文摘Pamula G Ekkad S V Acharya S 2001ASME Journal of Turbomachinery2001,123,2:1
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