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| 1 | Viral hepatitis update: Progress and perspectives显示文摘Viral hepatitis,secondary to infection with hepatitis A,B,C,D,and E viruses,are a major public health problem and an important cause of morbidity and mortality.Despite the huge medical advances achieved in recent years,there are still points of conflict concerning the pathogenesis,immune response,development of new and more effective vaccines,therapies,and treatment.This review focuses on the most important research topics that deal with issues that are currently being solved,those that remain to be solved,and future research directions.For hepatitis A virus we will address epidemiology,molecular surveillance,new susceptible populations as well as environmental and food detections.In the case of hepatitis B virus,we will discuss host factors related to disease,diagnosis,therapy,and vaccine improvement.On hepatitis C virus,we will focus on pathogenesis,immune response,direct action antivirals treatment in the context of solid organ transplantation,issues related to hepatocellular carcinoma development,direct action antivirals resistance due to selection of resistanceassociated variants,and vaccination.Regarding hepatitis D virus,we describe diagnostic methodology,pathogenesis,and therapy.Finally,for hepatitis E virus,we will address epidemiology(including new emerging species),diagnosis,clinical aspects,treatment,the development of a vaccine,and environmental surveillance. | María B Pisano Cecilia G Giadans Diego M Flichman Viviana E Ré María V Preciado Pamela Valva | 2021 | World Journal of Gastroenterology2021，27，26： | 8 |
| 2 | Prenatal diagnosis and assessment of congenital spinal anomalies: Review for prenatal counseling显示文摘The last two decades have seen continuous advances in prenatal ultrasonography and in utero magnetic resonance imaging. These technologies have increasingly enabled the identification of various spinal pathologies during early stages of gestation. The purpose of this paper is to review the range of fetal spine anomalies and their management, with the goal of improving the clinician's ability to counsel expectant parents prenatally. | Vidyadhar V Upasani Pamela Deaver Ketwaroo Judy A Estroff Benjamin C Warf John B Emans Michael P Glotzbecker | 2016 | World Journal of Orthopedics2016，7，7： | 4 |
| 3 | Chronic hepatitis C virus infection:Serum biomarkers inpredicting liver damage显示文摘Currently, a major clinical challenge in the management of the increasing number of hepatitis C virus(HCV) infected patients is determining the best means for evaluating liver impairment. Prognosis and treatment of chronic hepatitis C(CHC) are partly dependent on the assessment of histological activity, namely cell necrosis and inflammation, and the degree of liver fibrosis. These parameters can be provided by liver biopsy; however, in addition to the risks related to an invasive procedure, liver biopsy has been associated with sampling error mostly due to suboptimal biopsy size. To avoid these pitfalls, several markers have been proposed as non-invasive alternatives for the diagnosis of liver damage. Distinct approaches among the currently available non-invasive methods are(1) the physical ones based on imaging techniques; and(2) the biological ones based on serum biomarkers. In this review, we discuss these approaches with special focus on currently available non-invasive serum markers. We will discuss:(1) class?Ⅰ?serum biomarkers individually and as combined panels, particularly those that mirror the metabolism of liver extracellular matrix turnover and/or fibrogenic cell changes;(2) class Ⅱ biomarkers that are indirect serum markers and are based on the evaluation of common functional alterations in the liver; and(3) biomarkers of liver cell death, since hepatocyte apoptosis plays a significant role in the pathogenesis of HCV infection. We highlight in this review the evidence behind the use of these markers and assess the diagnostic accuracy as well as advantages, limitations, and application in clinical practice of each test for predicting liver damage in CHC. | Pamela Valva Daniela A Ríos Elena De Matteo Maria V Preciado | 2016 | World Journal of Gastroenterology2016，22，4： | 2 |
| 4 | Body shape assessment scale: instrument development for analyzing female figures 显示文摘 | Lenda J C Pamela V U Evelyn L | 2006 | Clothing and Textiles Research Journal2006，24，2： | 1 |
| 5 | Safety and effecacy of adefovir dipivoxil in patients infected with lamivudine-resistant hepatitis B and HIV-1显示文摘 | YVES B VINCENT T PAMELA V | 2006 | Hepatology2006，44，1： | 1 |
| 6 | Zero mortality after 152 consecutive pancreaticoduodenectomies with pancreaticogastrostomy显示文摘 | Gerard V Aranha Pamela J Hodul Steven Creech William Jacobs | 2003 | Journal of the American College of Surgeons2003，，2： | 1 |
| 7 | Subglottic secretion viscosity and evacuation effi ciency显示文摘 | Pamela V Cindy L | 2007 | Biological Research for Nursing2007，8，3： | 1 |
| 8 | Neurobiology of chronic mild stress: Parallels to major depression 显示文摘 | Matthew NH Kim GCH Pamela V | 2012 | Neurosci Biobehav Rev2012，36，9： | 1 |
| 9 | Sarcomatoid renal cell carcinoma显示文摘 | Arnoux V Lecbevallier E Pamela A | 2013 | Prog Urol2013，23，7： | 1 |
| 10 | Crystal structures of human cytochrome P450 3A4 bound to metyrapone and progesterone显示文摘 | PAMELA A W JOSE C DIJANA M V | 2004 | Science2004，305，5684： | 1 |
| 11 | Menthol cigarettes: setting the research agenda 显示文摘 | PAMELA I C PHILLIP S G MIRJANA V D | 2004 | Nicotine & Tob Res2004，6，1： | 1 |
| 12 | Comparing perceived burden for Korean and American informal caregivers of stroke survivors显示文摘 | Smi Choi-Kwon Pamela H Richard V | 2009 | Rehabil Nurs2009，34，4： | 1 |
| 13 | A survey on yeast microbiota associated with an Italian traditional sweet-leavened baked good fermentations显示文摘 | Pamela V Sara V | 2004 | Food Research International2004，37，： | 1 |
| 14 | Determinants of User Innovation and Innovation Sharing in a Local Market 显示文摘 | PAMELA D MORRISON J H R HIPPEL E V | 2000 | Management Sci- ence2000，46，12： | 1 |
| 15 | Global wa-ter resources:Vulnerability from climate change and populationgrowth显示文摘 | Charles J V Pamela Green Joseph Salisbury | 2000 | Science2000，289，5477： | 1 |
| 16 | Hepatic stem cells显示文摘 | Stuart F Pamela V Richard P | 2002 | Am J Pathol2002，197，5： | 1 |
| 17 | Thermodynamic control of gold nanocrystal sizee Experiment and theory显示文摘 | DANIEL V L PAMELA C O JAMES R H | 1995 | Phys Chem1995，99，18： | 1 |
| 18 | Sarcomatoid re- nal cell carcinoma显示文摘 | Arnoux V Lechevallier E Pamela A | 2013 | Prog Urol2013，23，7： | 1 |
| 19 | Differentiating between igutismspectrum disoorders and other developmental disabilities in children who failed a screening in strument for ASD显示文摘 | Pamela V Jamie Juhi | 2007 | JAutism Dev Disord2007，37，3： | 1 |
| 20 | IL-1 and IL-23 Mediate Early IL-17A Production in Pulmonary Inflammation Leading to Late Fibrosis显示文摘 | Pamela G Nicolas R Rachel V | 2011 | PLoS One2011，6，8： | 1 |
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