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| 1 | Whole-genome sequencing to detect mutations associated with resistance to insecticides and Bt proteins in Spodoptera frugiperda显示文摘The fall armyworm(FAW),Spodoptera frugiperda,is a major pest native to the Americas that has recently invaded the Old World.Point mutations in the target-site proteins acetylcholinesterase-1(ace-1),voltage-gated sodium channel(VGSC)and ryanodine receptor(RyR)have been identified in S.frugiperda as major resistance mechanisms to organophosphate,pyrethroid and diamide insecticides respectively.Mutations in the adenosine triphosphate-binding cassette transporter C2 gene(ABCC2)have also been identified to confer resistance to Cry IF protein.In this study,we applied a whole-genome sequencing(WGS)approach to identify point mutations in the target-site genes in 150 FAW individuals collected from China,Malawi,Uganda and Brazil.This approach revealed three amino acid substitutions(A201S,G227A and F290V)of S.frugiperda ace-1,which are known to be associated with organophosphate resistance.The Brazilian population had all three ace-1 point mutations and the 227A allele(mean frequency=0.54)was the most common.Populations from China,Malawi and Uganda harbored two of the three ace-1 point mutations(A201S and F290V)with the 290V allele(0.47-0.58)as the dominant allele.Point mutations in VGSC(T929I,L932F and L1014F)and RyR(I4790M and G4946E)were not detected in any of the 150 individuals.A novel 12-bp insertion mutation in exon 15 of the ABCC2 gene was identified in some of the Brazilian individuals but absent in the invasive populations.Our results not only demonstrate robustness of the WGS-based genomic approach for detection of resistance mutations,but also provide insights for improvement of resistance management tactics in S.frugiperda. | Fang Guan Jianpeng Zhang Huiwen Shen Xingliang Wang Amanda Padovan Tom K.Walsh Wee Tek Tay Karl H.J.Gordon William James Cecilia Czepak Michael Hilary Otim Donald Kachigamba Yidong Wu | 2021 | Insect Science2021，28，3： | 6 |
| 2 | Surface area and pore texture of catalysts显示文摘 | G Leofanti M Padovan G Tozzola B Venturelli | 1998 | Catalysis Today1998，，1： | 2 |
| 3 | Non-Linear Transient Analysis of Rotor-Casing Rub Events显示文摘 | Choy F K Padovan J | 1987 | Journal of Sound and Vibration1987，113，3： | 2 |
| 4 | Malignant gliomas actively recruit bone marrow stromal cells by secreting angiogenic cytokines显示文摘 | Tobias Birnbaum Julia Roider Christoph J. Schankin Claudio S. Padovan Christian Schichor Roland Goldbrunner Andreas Straube | 2007 | Journal of Neuro - Oncology2007，，3： | 2 |
| 5 | Characterization of protein hydrolysates prepared for enteral nutrition 显示文摘 | Freitas O Padovan G J Vilela L | 1993 | Agric Food Chem1993，41，： | 1 |
| 6 | Computational algorithms for FE formulations involving fractional operators显示文摘 | J. Padovan | 1987 | Computational Mechanics1987，，4： | 1 |
| 7 | Higher SOD1 gene expression in cumulus cells from infertile women with moderate and severe endometriosis显示文摘 | Donabela FC Meola J Padovan CC | 2015 | Reprod Sci2015，22，11： | 1 |
| 8 | p53 gene mutations and protein nuclear accumulation are early events in intestinal type gastric cancer but late events in diffuse type 显示文摘 | Luinetti O Padovan LS | 1995 | Cancer Epidemiol Biomarkers Prev1995，4，： | 1 |
| 9 | Physiology of geosmin production by Anabaena circinalis isolated from the Murrumbidgtee River, Australia显示文摘 | BOWMER K H PADOVAN A OLIVER R L | 1992 | Water Science and Technology1992，25，： | 1 |
| 10 | Semi - analytical finite element procedure for con- duction in anisotropic axisymmetric solids 显示文摘 | Padovan J | 1974 | International Journal for Numerical Methods in Engineering1974，，8： | 1 |
| 11 | Angiitis of the central nervous system after allogeneic bone marrow transplantation 显示文摘 | Padovan CS Bise K Hahn J | 1999 | Stroke1999，30，8： | 1 |
| 12 | Recent advances and perspective in neuroimaging in neuropsychiatric systemic lupus erythematosus显示文摘 | Govoi M Castellino G Padovan M | 2004 | Lupus2004，13，3： | 1 |
| 13 | Surface area and pore texture of catalysts 显示文摘 | Leofanti M Padovan G Tozzola Venturelli B | 1998 | Catal Today1998，41，： | 1 |
| 14 | Grain yield, nitrogen-use efficiency and baking quality of old and modem Italian bread- wheat cultivars grown at different nitrogen levels显示文摘 | Guarda G Padovan S Delogu G | 2004 | Euro- pean Journal of Agronomy2004，21，2： | 1 |
| 15 | Fungi evolution revisited: Application of the penalized likelihood method to a Bayesian fungal phylogeny provides a new perspective on phylogenetic relationships and divergence dates of Ascomycota groups 显示文摘 | Padovan A C B Sanson G F O Brunstein A Briones M R S | 2005 | J Mol Evol2005，60，： | 1 |
| 16 | Three-dimensional finite element stress analysis of the polypropylene, ankle-foot orthosis: static analysis显示文摘 | Chu TM Reddy NP Padovan J | 1995 | Med Eng Phys1995，17，5： | 1 |
| 17 | IFN - α2α induces IP- 10/CXCLIO and MIG/CXCL9 production in monocyte -derived dendritic ceils and enhances their capacity to attract and stimulate CD8 + effector T cells 显示文摘 | Padovan E Spagnoli GC Ferrantini M | 2002 | J Leukoc Biol2002，71，4： | 1 |
| 18 | Computational algorithms for FE formulations involving fractional operators 显示文摘 | Padovan J | 1987 | Computational Mechanics1987，2，4： | 1 |
| 19 | Expression of neuronal markers in differentiated marrow stromal cells and CD133 ~ stem - like cells 显示文摘 | PADOVAN C S JAHN K BIRNBAUM T | 2003 | Cell Transplant2003，12，8： | 1 |
| 20 | Detection of adulteration of commercial honey samples by the 13C/12C isotopic ratio 显示文摘 | PADOVAN G J JONG D D RODRIGUES L P | 2003 | Food Chemistry2003，82，4： | 1 |
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