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| 1 | Osteosarcopenia in autoimmune cholestatic liver diseases:Causes,management,and challenges显示文摘Primary biliary cholangitis and primary sclerosing cholangitis(PSC)are the most common cholestatic liver diseases(CLD)in adults and are both characterized by an immune pathogenesis.While primary biliary cholangitis is a model autoimmune disease,with over 90%of patients presenting very specific autoantibodies against mitochondrial antigens,PSC is considered an immune mediated disease.Osteoporosis is the most common bone disease in CLD,resulting in frequent fractures and leading to significant morbidity.Further,sarcopenia is emerging as a frequent complication of chronic liver diseases with a significant prognostic impact and severe implications on the quality of life of patients.The mechanisms underlying osteoporosis and sarcopenia in CLD are still largely unknown and the association between these clinical conditions remains to be dissected.Although timely diagnosis,prevention,and management of osteosarcopenia are crucial to limit the consequences,there are no specific guidelines for management of osteoporosis and sarcopenia in patients with CLD.International guidelines recommend screening for bone disease at the time of diagnosis of CLD.However,the optimal monitoring strategies and treatments have not been defined yet and vary among centers.We herein aim to comprehensively outline the pathogenic mechanisms and clinical implications of osteosarcopenia in CLD,and to summarize expert recommendations for appropriate diagnostic and therapeutic approaches. | Nicola Pugliese Ivan Arcari Alessio Aghemo Andrea G Lania Ana Lleo Gherardo Mazziotti | 2022 | World Journal of Gastroenterology2022，28，14： | 2 |
| 2 | The Chronic Kidney Disease Epidemiology Collaboration ( CKD- EPI ) e- quation provides a better definition of cardiovascular burden associated with CKD than the Modification of Diet in Renal Disease( MDRD)Study formula in subjects with type 2 dia- betes显示文摘 | PUGLIESE G SOLINI A BONORA E | 2011 | Atherosclerosis2011，218，1： | 1 |
| 3 | Endoscopic retrograde forceps biopsy and brush cytology of biliary structure : a prospective study显示文摘 | Pugliese V Conio M Nicolo G | 1995 | Gastrointest Endosc1995，42，6： | 1 |
| 4 | Interaction of human plasma fibronectin with viral proteins of human immunodeficiency virus显示文摘 | Torre D Pugliese A Ferrario G | 1994 | FEMS Immunol Med Microbiol1994，8，2： | 1 |
| 5 | Diagnostic accuracy of non-invasive 64-slice CT coronary angiography in patients with stable angina pectoris 显示文摘 | Pugliese F Mollet NR Runza G | 2006 | Eur Radiol2006，16，： | 1 |
| 6 | The chronic kidney disease ep- idemiology collaboration ( CKD - EPI) equation provides a better defi- nition of cardiovascular burden associated with CKD than the modifi- cation of diet in renal disease (MDRD) study formula in subjects with type 2 diabetes 显示文摘 | Pugliese G Solini A Bonora E | 2011 | Atherosclerosis2011，218，： | 1 |
| 7 | Tricuspid valve annuloplasty using a partial flexible ring:mid-term follow-up显示文摘 | Pacilli P Pugliese P | 2003 | Ital Heart J2003，4，2： | 1 |
| 8 | Updating the natural history of diabetic nephropathy 显示文摘 | Pugliese G | 2014 | Acta Diabetol2014，51，6： | 1 |
| 9 | Diagnostic accuracy of non-invasive 64-slice CT coronary angiography in patients with stable angina pectoris显示文摘 | Pugliese F Mollet NR Runza G | 2006 | Eur Radiol2006，16，3： | 1 |
| 10 | Diagnostic: accuracy of non-invasive 64-slice CT coronary angiography in patients with stable angina pectoris 显示文摘 | Pugliese F Mollet NR Runza G | 2006 | Eur Radio2006，16，3： | 1 |
| 11 | Funetional sequ- elae f'ol]owing bilatera] mastectomy and immediate re- construction with latissimus dorsi flap: medium-term foIlow-up显示文摘 | Paolini G Amoroso M Pugliese P | 2014 | Plast Surg Hand Surg2014，48，99： | 1 |
| 12 | Accelerated diabetic glomerulopathy in galectin-3/AGE receptor 3 knockout mice显示文摘 | Pugliese G Pricci F Iacobini C | 2001 | FASEB2001，15，： | 1 |
| 13 | Alteration of complex Ⅳ and acetylcholine-related enzymes in experimental spinal cord injury显示文摘 | Brambilla G Sangiovanni G Pugliese R | 1996 | J Neurosurg Sci1996，40，34： | 1 |
| 14 | Effect of temperature and soil on Ortho-phthalaldehyde solution 显示文摘 | Favero MS | 2000 | Infection Control and Hospital Epidemiology2000，21，8： | 1 |
| 15 | Diagnostic accuracy of noninvasive 64-slice CT coronary angiography in patients with stable angina pectoris显示文摘 | Pugliese F Mollet NR Runza G | 2006 | Eur Radiol2006，16，3： | 1 |
| 16 | CT angiography versus colour-Doppler US in acute dissection of the vertebral artery显示文摘 | Pugliese F Crusco F Cardaioli G | | 0，，： | 1 |
| 17 | Devel- opmental patterns within a muhispecies reef fishery: manage- ment applications for essential fish habitats and protected areas显示文摘 | LINDEMAN K C PUGLIESE R WAUGH G T | 2000 | Bulletin of Marine Science2000，66，3： | 1 |
| 18 | Diagnostic accu- racy of noninvasive 64-slice CT coronary angiography in patients with stable angina pectoris 显示文摘 | Pugliese F Mollet NR Runza G | 2006 | Eur Radiol2006，16，3： | 1 |
| 19 | Implementation of epidural analgesia for labor:is the standard of effective analgesia reachable in all women An audit of two years显示文摘 | Pugliese PL Cinnella G Raimondo P | | 0，，09： | 1 |
| 20 | Histone deacetylase inhibition modulates e-cadherin expression and suppresses migration and invasion of anaplastic thyroid cancer cells显示文摘 | Catalano M G Fortunati N Pugliese M | 2012 | J Clin Endocrinol Metab2012，97，7： | 1 |
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