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| 1 | Triglyceride levels and apolipoprotein E polymorphism in patients with acute pancreatitis显示文摘BACKGROUND:Hypertriglyceridemia is an unusual cause of acute pancreatitis and sometimes considered to be an epiphenomenon.This study aimed to investigate the clinical and analytical features and the APOE genotypes in patients with acute pancreatitis and severe hypertriglyceridemia.METHODS:We undertook a one-year,prospective study of patients with acute pancreatitis whose first laboratory analysis on admission to the emergency department included measurement of serum triglycerides.The APOE genotype was determined and the patients answered an established questionnaire within the first 24 hours concerning their alcohol consumption,the presence of co-morbidities and any medications being taken.The patients' progression,etiological diagnosis,hospital stay and clinical and radiological severity were all recorded.RESULTS:Hypertriglyceridemia was responsible for 7 of 133 cases of pancreatitis (5%);the remaining cases were of biliary (53%),idiopathic (26%),alcoholic (11%) or other (5%) origin.Compared with these remaining cases,the patients with hypertriglyceridemia were significantly younger,had more relapses,and more often had diabetes mellitus.They usually consumed alcohol or consumed it excessively on the days before admission.Also,the ε4 allele of the APOE gene was more common in this group (P<0.05).CONCLUSION:One of 20 episodes of acute pancreatitis is caused by hypertriglyceridemia and it is linked to genetic (ε4 allele) and comorbid factors such as diabetes and,especially,alcohol consumption. | Radka Ivanova Susana Puerta Alfonso Garrido Ignacio Cueto Ana Ferro María José Ariza Andrés Cobos Pedro González-Santos Pedro Valdivielso | 2012 | Hepatobiliary & Pancreatic Diseases International2012，11，1： | 26 |
| 2 | Nuclear domain 10 of the viral aspect显示文摘Nuclear domain 10(ND10) are spherical bodies distributed throughout the nucleoplasm and measuring around 0.2-1.0 μm. First observed under an electron microscope, they were originally described as dense bodies found in the nucleus. They are known by a number of other names, including Promyelocytic Leukemia bodies(PML bodies), Kremer bodies, and PML oncogenic domains. ND10 are frequently associated with Cajal bodies and cleavage bodies. It has been suggested that they play a role in regulating gene transcription. ND10 were originally characterized using human autoantisera, which recognizes Speckled Protein of 100 kD a, from patients with primary biliary cirrhosis. At the immunohistochemical level, ND10 appear as nuclear punctate structures, with 10 indicating the approximate number of dots per nucleus observed. ND10 do not colocalize with kinetochores, centromeres, sites of mR NA processing, or chromosomes. Resistance of ND10 antigens to nuclease digestion and salt extraction suggest that ND10 are associated with the nuclear matrix.They are often identified by immunofluorescent assay using specific antibodies against PML, Death domainassociated protein, nuclear dot protein(NDP55), and so on. The role of ND10 has long been the subject of investigation, with the specific connection of ND10 and viral infection having been a particular focus for almost 20 years. This review summarizes the relationship of ND10 and viral infection. Some future study directions are also discussed. | Yisel A Rivera-Molina Francisco Puerta Martínez Qiyi Tang | 2013 | World Journal of Virology2013，2，3： | 7 |
| 3 | Alkali-activated slag cements:kinetic studies显示文摘 | FERNANDEZ-JIMENEZ A PUERTAS F | 1997 | Cem Concr Res1997，27，3： | 1 |
| 4 | Leptin administration to cold acclimated rats reduces both food intake and brown adipose tissue thermogenesis 显示文摘 | Abelenda M Ledesma A Rial E Puerta M | 2003 | Journal of Thermal Biology2003，28，： | 1 |
| 5 | Colloidal Stability of Polymer Colloids with Variable Surface Charge 显示文摘 | PUERTAS A M NIEVES F J D L | 1999 | Journal ofColloid and Interface Science1999，216，2： | 1 |
| 6 | Determination of kinetic equations of alkaline activation of blast furnace slag by means of calorimetric data显示文摘 | FERNANDEZ-JIMENEZ A PUERTAS F ARTEAGA A | 1998 | J Therm Anal Calori1998，52，2： | 1 |
| 7 | Development of an immunochromatographic method to determineβ–lactoglobulin at trace levels显示文摘 | Puerta A Diez–Masa J C Frutos M | 2005 | Analytica Chimica Acta2005，537，： | 1 |
| 8 | Determination of volatile aldehydes forevaluafionof in vitro antioxidant activity 显示文摘 | Elena E Stashenko M A Puertas J R | 2002 | Anal Bioanal Chem2002，373，： | 1 |
| 9 | A GRASP algorithm for fast hybrid (filterwrapper) feature subset selection in highdimensional datasets显示文摘 | BERMEJO P GMEZ J A PUERTA J M | 2011 | Pattern Recognition Letters2011，32，5： | 1 |
| 10 | Copper tolerance mediated by polyphosphate degradation and low - af- finity inorganic phosphate transport system in Escherichia coli 显示文摘 | Grillo - Puertas M Schurig - Briccio L A Rodriguez - Montelongo L | 2014 | BMC Microbiol2014，14，： | 1 |
| 11 | Bakri balloon for the management of postpartum hemorrhage 显示文摘 | AIBAR L AGUILAR MT PUERTAS A | 2013 | Acta obstetricia et gynecologica Scandinavica2013，92，4： | 1 |
| 12 | Martfnez SPME determination of volatile aldehydes for evaluation of in - vitro antioxidant activity 显示文摘 | Elena E Stashenko Miguel A Puertas Jairo R | 2002 | Anal Bioanal Chem2002，373，： | 1 |
| 13 | Alkaliaggregate behaviour of alkali-activated slag mortars: effect of aggregate type显示文摘 | Puertas F Palacios M Gil-maroto A | 2009 | Cement and Concrete Composites2009，31，5： | 1 |
| 14 | Neuro- immune interactions via the cholinergic anti - inflammatory pathway 显示文摘 | GALLOWITSCH PUERTA M PAVLOV V A | 2007 | Life Sci2007，80，2425： | 1 |
| 15 | Inhibition of HIV-1 replication by RNA targeted against the LTR region显示文摘 | Barroso A Romero C | 2005 | AIDS2005，19，9： | 1 |
| 16 | Ceramic wastes as alternative raw materials for Portland cement clinker production显示文摘 | Puertas F Garcia-Diaz I Barba A | 2008 | Cement & Concrete Composites2008，30，： | 1 |
| 17 | Identification and functional analysis of pistil self-incompatibility factor HT-B of Petunia显示文摘 | PUERTA A R USHUIMA K KOKA T SASSA H | 2009 | Journal of Experimental Botany2009，60，4： | 1 |
| 18 | Bakri balloon for the man- agement of postpartum hemorrhage显示文摘 | Aibar L Aguilar M T Puertas A | 2013 | Acta Obstet Gynecol2013，92，： | 1 |
| 19 | A study of industry evolution in the face of maior environmental disturbances: group and firm strategic behavior of Spanish banks, 1983-1997显示文摘 | ZUNIGA-VICENTE J A FUENTE-SABATE J M RO DRIGUEZ PUERTA J | 2004 | British Journal of Management2004，，： | 1 |
| 20 | Martinez SPME determination of volatile aldehydes for evaluation of in - vitro antioxidant activity 显示文摘 | Elena E Stashenko Miguel A Puertas Jairo R | 2002 | Anal Bioanal Chem2002，373，： | 1 |
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