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	题名	作者	年代	出处	被引量
1	Synthesis and evaluation of novel analogues of mangiferin as potent antipyretic显示文摘Objective:To screen different analogues of mangiferin pharmacologically for antipyretic activity. Methods:The naturally occurring xanthone glycoside mangiferin was isolated by column chromatography from the elhanolic extract of stem bark of Mangifera indica.Mangiferin was further converted to 5-(N-phenylamino methyleno) mangiferin.5-(N-p-chlorophenylamino methyleno) mangiferin,5-(N-2-methyl phenylamino methyleno) mangiferin.5-(N-p-methoxy phenylamino methyleno) mangiferin.5-(N,N-diphenylamino methyleno) mangiferin,5-(N-α-napthylamino methyleno) mangiferin and 5-(N-4-methyl phenylamino methyleno) mangiferin analogues.The synthesized compounds were further screened for antipyretic activity along with mangiferin at a dose level of 100 and 200 tng/kg.Mangiferin and its analogues were characterized by melting point and R_f value determination and through spectral technique like UV,IR,and NMR spectral analysis.Results:The antipyretic activity of mangiferin as well as all analogues was found to be more significant in at higher dose ie.200 mg/kg which was depicted thmugh a decrease in rectal temperature up to 3 h.Conclusions:The antipyretic activity of mangiferin and its analogues may be attributed to inhibition in synthesis of TNF-αand anti-oxidant activity associated with amelioration of inflammatory actions of cytokines.	Shashi Kant Singh Saurabh K Sinha SK Prasad R Kumar Bhawani S Bithu S Sadish Kumar P Singh	2011	Asian Pacific Journal of Tropical Medicine2011，4，11：	4
2	Study of fractional softening in multi-stage hot deformation显示文摘	Rao K P Prasad Y K D V Hawboly E B	1998	J Mater Process Tech1998，77，13：	1
3	Simulation of Frontal Barrier Offset Impacts and Comparison of Intrusions and Decelerations 显示文摘	SAHA N K CALSO S M PRASAD P	1995	SAE Transactions1995，104，1：	1
4	Purification and partial chara -ctcrization of thcrmostablc scrinc alkaline protease from a newly isolated Bacillus subtilis PE-11 显示文摘	ADINARAYANA K ELLAIAH P PRASAD D S	2003	AAPS Pharmaceutical Science and Technology2003，4，4：	1
5	Zinc biosorption on Tectona grandis L leaves biomass:Equilibrium and kinetic studies显示文摘	Kumar Y P King P Prasad V S R K	2006	Chemical Engineering Journal2006，124，1：	1
6	Effect of zine on free radicals and proline in Brassica and Cajanus显示文摘	Alia K V Prasad S K Saradhi P P	1995	Phytochemistry1995，39，：	1
7	Efficacy of levamisole as an immunostimulant in Macrobrachium Rosenbergii ( De man ) 显示文摘	Baruah N D Prasad K P	2001	J Aquac Trop2001，16，：	1
8	Effect of zinc on free radicals and proline in Brassica and Cajanus显示文摘	Alia Prasad K V S K Saradhi P P	1995	Phytochemistry1995，39，1：	1
9	Voltammetric sensor for barbituric acid based on a solgel derivated molecularly imprinted polymer brush grafted to graphite electrode显示文摘	PATEL A K SHARMA P S PRASAD B B	2009	International Journal of Pharmaceutics2009，371，1：	1
10	Enhanced tolerance to photoinhibition in transgenic plants through targeting of glycinebetaine biosynthesis into the chloroplasts显示文摘	Prasad K V S K Saradhi P P	2004	Plant Science2004，166，5：	1
11	Rigid nasal en- doscopy in the diagnosis and treatment of epistaxis 显示文摘	Kumar M V V Prasad K U R Gowda P R B	2013	J Clin Diagn Res2013，7，5：	1
12	Evidence for chilling induced oxidative stress in maize seedlings and a regulatory role for hydrogen peroxide显示文摘	Prasad T K Anderson M P Martin B A	1994	Plant Cell1994，6，：	1
13	A Study on Curing between Shellac and Polyamide Resin by Dielectric Measurements显示文摘	K M Prasad P C Jha	2003	Asian Journal of Chemistry2003，15，3：	1
14	The phase mixing of moisture cured polyurethane-urea during cure显示文摘	Chattopadhyay D K Prasad P S R Sreedhar B	2005	Progress in Organic Coatings2005，54，4：	1
15	Ion imprinted polymer based sensor for monitoring toxic uranium in environmental samples 显示文摘	Metilda P Prasad K Kala R	2007	Analytica Chimica Acta2007，582，：	1
16	Evaluation of Bacillus subtilis as a probiotic to Indian major carp Labeo rohita 显示文摘	Kummar R Mukherjee S C Prasad K P	2006	Aquaculture Research2006，37，12：	1
17	Processing maps for hot deformation of rolled AZ31 magnesium alloy plate:anisotropy of hot workability 显示文摘	Prasad Y V R K Rao K P	2008	Materials Science and Engineering2008，487，：	1
18	Processing maps and rate control ling mechanisms of hot deformation of electrolytic tough pitch copper in the temperature range 300-950℃显示文摘	PRASAD Y V R K RAO K P	2005	Materials Science and Engineering: A2005，391，12：	1
19	Single nueleotide polymorphisms: a new paradigm for molecular marker technology and DNA polymorphism detection with emphasis on their use in plants显示文摘	Gupta P K Roy J K Prasad M	2001	Currret Science2001，80，：	1
20	Interface crack around circular inclusion: SIF, kinking, debonding energetics 显示文摘	Prasad P B N Simha K R Y	2003	Engineering Fracture Mechanics2003，70，：	1

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