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| 1 | A review on medicinal importance,pharmacological activity and bioanalytical aspects of beta-carboline alkaloid 'Harmine'显示文摘Harmine,a beta-carboline alkaloid,is widely distributed in the plants,marine creatures,insects, mammalians as well as in human tissues and body fluids.Harmine was originally isolated from seeds of Peganum harmal in 1847 having a core indole structure and a pyridine ring.Harmine has various types of pharmacological activities such as antimicrobial,antifungal,antitumor,cytotoxic, antiplasmodial,antioxidaant,antimutagenic,antigenotoxic and hallucinogenic properties.It acts on gamma-aminobutyric acid type A and monoamine oxidase A or B receptor,enhances insulin sensitivity and also produces vasorelaxant effect.Harmine prevents bone loss by suppressing osteoclastogenesis.The current review gives an overview on pharmacological activity and analytical techniques of harmine,which may be useful for researcheres to explore the hidden potential of harmine and and will also help in developing new drugs for the treatment of various diseases. | K Patel M Gadewar R Tripathi SK Prasad Dinesh Kumar Patel | 2012 | Asian Pacific Journal of Tropical Biomedicine2012，2，8： | 17 |
| 2 | Assessment of the diagnostic performance and interobserver variability of endocytoscopy in Barrett's esophagus:A pilot ex-vivo study显示文摘AIM:To investigate a classification of endocytoscopy(ECS)images in Barrett’s esophagus(BE)and evaluate its diagnostic performance and interobserver variability.METHODS:ECS was applied to surveillance endoscopic mucosal resection(EMR)specimens of BE ex-vivo.The mucosal surface of specimen was stained with 1%methylene blue and surveyed with a catheter-type endocytoscope.We selected still images that were most representative of the endoscopically suspect lesion and matched with the final histopathological diagnosis to accomplish accurate correlation.The diagnostic performance and inter-observer variability of the new classification scheme were assessed in a blinded fashion by physicians with expertise in both BE and ECS and inexperienced physicians with no prior exposure to ECS.RESULTS:Three staff physicians and 22 gastroenterology fellows classified eight randomly assigned unknown still ECS pictures(two images per each classification)into one of four histopathologic categories as follows:(1)BEC1-squamous epithelium;(2)BEC2-BE without dysplasia;(3)BEC3-BE with dysplasia;and(4)BEC4-esophageal adenocarcinoma(EAC)in BE.Accuracy of diagnosis in staff physicians and clinical fellows were,respectively,100%and 99.4%for BEC1,95.8%and83.0%for BEC2,91.7%and 83.0%for BEC3,and95.8%and 98.3%for BEC4.Interobserver agreement of the faculty physicians and fellows in classifying each category were 0.932 and 0.897,respectively.CONCLUSION:This is the first study to investigate classification system of ECS in BE.This ex-vivo pilot study demonstrated acceptable diagnostic accuracy and excellent interobserver agreement. | Yutaka Tomizawa Prasad G Iyer Louis M Wongkeesong Navtej S Buttar Lori S Lutzke Tsung-Teh Wu Kenneth K Wang | 2013 | World Journal of Gastroenterology2013，19，46： | 2 |
| 3 | Cardiovascular magnetic resonance: Diagnostic utility and specific considerations in the pediatric population显示文摘Cardiovascular magnetic resonance is a non-invasive imaging modality which is emerging as important tool for the investigation and management of pediatric cardiovascular disease. In this review we describe the key technical and practical differences between scanning children and adults, and highlight some important considerations that must be taken into account for this patient population. Using case examples commonly seen in clinical practice, we discuss the important clinical applications of cardiovascular magnetic resonance, and briefly highlight key future developments in this field. | Frances M Mitchell Sanjay K Prasad Gerald F Greil Peter Drivas Vassilios S Vassiliou Claire E Raphael | 2016 | World Journal of Clinical Pediatrics2016，5，1： | 2 |
| 4 | Simulation of Frontal Barrier Offset Impacts and Comparison of Intrusions and Decelerations 显示文摘 | SAHA N K CALSO S M PRASAD P | 1995 | SAE Transactions1995，104，1： | 1 |
| 5 | Synthesis of a re- usable oxotungsten-containing SBA-15 mesoporous catalyst for the organic solvent-free conversion of cyclohexene to a- dipic acid显示文摘 | Cheng C Y Lin K J Prasad M R | 2007 | Catal Commun2007，8，7： | 1 |
| 6 | Experimen- tal study of an air-cooled thermal rnanagement system for high capacity lithium-titanate batteries 显示文摘 | Giuliano M R Ajay Prasad K Advani S G | 2012 | Journal of Power Sources2012，216，： | 1 |
| 7 | Characteriza- tion of phosphorus fractions in the sediments of a tropical in- tertidal mangrove ecosystem显示文摘 | BALA K PRASAD M R AM AN ATH AN A L | 2010 | Wetland Ecology and Man- agement2010，18，2： | 1 |
| 8 | Evidence for chilling-induced oxidative stress in maize seedlings and a regulatory role for hydrogen peroxide显示文摘 | Prasad T K Anderson M D Martin B A | 1994 | Plant Cell1994，6，： | 1 |
| 9 | Adsorption of benzaldehyde on granular activated carbon:Kinetics,equilibrium,andthermodynamic source显示文摘 | Rajoriya R K Prasad B Mishra I M | 2007 | Chemical and Biochemical Engineering Quarterly2007，21，3： | 1 |
| 10 | Rigid nasal en- doscopy in the diagnosis and treatment of epistaxis 显示文摘 | Kumar M V V Prasad K U R Gowda P R B | 2013 | J Clin Diagn Res2013，7，5： | 1 |
| 11 | Evidence for chilling- induced oxidative stress in maize seedlings and a regulatory role for hydrogen peroxide 显示文摘 | Prasad T K Anderson M D Martin B A | 1994 | The Plant Cell1994，，6： | 1 |
| 12 | Insights into heap bioleaching of low grade chalcopyrite ores--A pilot scale study显示文摘 | PANDA S SAN JAY K SUKLA L B PRADHAN N SUBBAIAH T MISHRA B K PRASAD M S R RAY S K | 2012 | Hydrometallurgy2012，125，： | 1 |
| 13 | Differential gene expression in chilling-acclimated maize seedlings and evidence for the involvement of abscisic acid in chilling tolerance显示文摘 | Anderson M D Prasad T K Martin B A | 1994 | Plant Physiol1994，105，： | 1 |
| 14 | Inter-conversion of 1-D coordination polymers in the Ce-Sr-dipicH2 syntem(dipicH2=dipicolinic acid)显示文摘 | Prasad T K Rajasekharan M V | 2005 | Inorg Chem Comm2005，8，12： | 1 |
| 15 | Evidence for chilling induced oxidative stress in maize seedlings and a regulatory role for hydrogen peroxide显示文摘 | Prasad T K Anderson M P Martin B A | 1994 | Plant Cell1994，6，： | 1 |
| 16 | A Study on Curing between Shellac and Polyamide Resin by Dielectric Measurements显示文摘 | K M Prasad P C Jha | 2003 | Asian Journal of Chemistry2003，15，3： | 1 |
| 17 | Modeling of dynamic material behavior in hot deformation:Forging of Ti-6242显示文摘 | Prasad Y V R K Gegel H L Doraivelu S M | | 0，，10： | 1 |
| 18 | Prediction of grain size of Al-7Si alloy by neural networks 显示文摘 | REDDY N S PRASAD R A K CHAKRABORTY M MURTY B S | 2005 | Materials Science and Engineering A2005，391，： | 1 |
| 19 | Differential methods for the performance prediction of multistream plate-fin heat exchangers显示文摘 | Prasad B S V Gurukul S M K A | 1992 | Journal of Heat Transfer1992，114，1： | 1 |
| 20 | Single nueleotide polymorphisms: a new paradigm for molecular marker technology and DNA polymorphism detection with emphasis on their use in plants显示文摘 | Gupta P K Roy J K Prasad M | 2001 | Currret Science2001，80，： | 1 |
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