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| 1 | Miniature gastrointestinal endoscopy: Now and the future显示文摘Since its original application,gastrointestinal(GI)endoscopy has undergone many innovative transformations aimed at expanding the scope,safety,accuracy,acceptability and cost-effectiveness of this area of clinical practice.One method of achieving this has been to reduce the caliber of endoscopic devices.We propose the collective term“Miniature GI Endoscopy”.In this Opinion Review,the innovations in this field are explored and discussed.The progress and clinical use of the three main areas of miniature GI endoscopy(ultrathin endoscopy,wireless endoscopy and scanning fiber endoscopy)are described.The opportunities presented by these technologies are set out in a clinical context,as are their current limitations.Many of the positive aspects of miniature endoscopy are clear,in that smaller devices provide access to potentially all of the alimentary canal,while conferring high patient acceptability.This must be balanced with the costs of new technologies and recognition of device specific challenges.Perspectives on future application are also considered and the efforts being made to bring new innovations to a clinical platform are outlined.Current devices demonstrate that miniature GI endoscopy has a valuable place in investigation of symptoms,therapeutic intervention and screening.Newer technologies give promise that the potential for enhancing the investigation and management of GI complaints is significant. | John J McGoran Mark E McAlindon Prasad G Iyer Eric J Seibel Rehan Haidry Laurence B Lovat Sarmed S Sami | 2019 | World Journal of Gastroenterology2019，25，30： | 4 |
| 2 | Long Term Salinity Stress Reveals Variety Specific Differences in Root Oxidative Stress Response显示文摘Salinity stress induces oxidative stress caused by reactive oxygen species(ROS):superoxide radicals,hydrogen peroxide(H2O2) and hydroxyl radicals.Activities of both enzymatic and non-enzymatic components of the antioxidant system and related growth parameters were studied in the roots of the salt tolerant rice variety FL478 and the sensitive variety IR29 in response to long term stress(12 d) induced by 50 mmol/L NaCl.The comparative study showed that FL478 maintained higher relative growth rate and lower Na+/K+ in the roots than IR29 due to a higher membrane stability index that effectively exclude Na+.Lower TBARS(thiobarbituric acid reactive substance) content in FL478 roots indicated that its membrane was relatively unaffected by ROS despite high H2O2 content recorded under the salinity stress.Relatively higher superoxide dismutase activity along with a parallel increase in transcript level of superoxide dismutase(Os07g46990) in FL478 indicated that this protein might make a vital contribution to salt stress tolerance.Although the content of ascorbic acid remained unchanged in FL478,the activity of ascorbic peroxidases(APOXs) was reduced comparably in the both varieties.Transcriptomic data showed that a larger number of peroxidase genes were upregulated in FL478 compared to IR29 and several of which might provide engineering targets to improve rice salt tolerance. | Prasad SENADHEERA Shamala TIRIMANNE Frans J M MAATHUIS | 2012 | Rice science2012，19，1： | 3 |
| 3 | Treatment of simulated Reactive Yellow 22 (Azo) dye effluents using Spirogyra species 显示文摘 | Mohan S V Rao N C Prasad K K J | 2002 | Waste Management2002，22，6： | 1 |
| 4 | Elevated serum levels of transforming growth factor beta1 in Epstein-Barr virus-associated nasopharyngeal carcinoma patients 显示文摘 | Menezes J Prasad U | 1999 | Int J Cancer1999，84，4： | 1 |
| 5 | Modular product design: A life cycle view 显示文摘 | GERSHENSON J K PRASAD G J ALLAMNENI S | 1999 | Journal of Integrated Design and Process Science1999，3，4： | 1 |
| 6 | Characterization of a MENI ortholog from Drosophila melanogaster显示文摘 | Guru S C Prasad N B Shin E J | 2001 | Gene2001，263，： | 1 |
| 7 | Establishment of primary cUltures of rat and human parotid epithelial cells for transfection experiment显示文摘 | Prasad KN Edwards-Prasad J Carvalho E | 1992 | In Vitro Cell Dev Biol1992，28，78： | 1 |
| 8 | Radioprotective effeats of diltiazem on cytogenetic damage and survival in gamma ray exposed mice显示文摘 | Goel HC Ganguly SK Prasad J | 1996 | Indian J Expertal Bio1996，34，12： | 1 |
| 9 | Synthesis of a re- usable oxotungsten-containing SBA-15 mesoporous catalyst for the organic solvent-free conversion of cyclohexene to a- dipic acid显示文摘 | Cheng C Y Lin K J Prasad M R | 2007 | Catal Commun2007，8，7： | 1 |
| 10 | Benzoyl Cyanide: A Mild and Efficient Reagent for Benzoylation of Nucleosides 显示文摘 | PRASAD A K KUMAR V MAITY J | 2005 | Synthetic Communications2005，35，： | 1 |
| 11 | NF-κB and cancer: how intimate is this relationship 显示文摘 | Prasad S Ravindran J Aggarwal BB | 2010 | Mol Cell Biochem2010，336，12： | 1 |
| 12 | Mammalian base excision repair: functional partnership between PARP - 1 and APE - 1 in AP - site repair显示文摘 | Prasad R Dyrkheeva N Williams J | 2015 | PLoS One2015，10，12： | 1 |
| 13 | Cardiovascular Magnetic Resonance in Cardiac Amyloidosis显示文摘 | Maceira AM Joshi J Prasad SK | 2005 | Circulation2005，111，2： | 1 |
| 14 | Cloning of the sodium-dependent,broad-scope,neutral amino acid transporter Bo from a human placental choriocarcinoma cell line显示文摘 | Kekuda R Prasad P D Fei Y J | 1996 | Biol Chem1996，271，18： | 1 |
| 15 | Safe administration of etoposide phosphate after hypersensitivity reaction to intravenous etoposide显示文摘 | Siderov J Prasad P De Boer R | 2002 | Br J Cancer2002，86，1： | 1 |
| 16 | Treatment of Simulated Reactive Yellow 22 (Azo) Dye Effluents Using Spirogyra Species 显示文摘 | VENKATA MOHAN S CHANDRASEKHAR RAO N KRISHNA PRASAD K KARTHIKEYAN J | 2002 | Waste Management2002，22，： | 1 |
| 17 | Modular Product Design : A Life - cycle View 显示文摘 | GERSHENSON J PRASAD J ALLAMNENI S | 1999 | Journal of Integrated Design and Process Science1999，3，4： | 1 |
| 18 | Adult rat ventricular myocytes cultured in defined medium: phenotype and electromechanical function 显示文摘 | ELLINGSEN O DAVIDOFF A J PRASAD S K | 1993 | AmJ Physiol1993，265，： | 1 |
| 19 | The Cox maze IIIproce- dure for atrial fibrillation: Long-term efficacy in patients undergoin- glone versus concomitant procedure 显示文摘 | Prasad SM Maniar HS Camillo C J | 2003 | J Thorac Cardiovasc Surg2003，126，6： | 1 |
| 20 | Antidyslipidemie and antioxidant activity of an unusual amino acid (2-amino-5-hydroxyhexanoie acid ) isolated from the seeds of Crotalaria juncea显示文摘 | PRASAD J SINGH V K SHRIVASTAVA A | 2013 | Phytomedicine2013，21，1： | 1 |
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