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210篇 您的检索式:作者名="POUWEL"
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1儿童早期发展综合干预策略对改善贫困农村地区0~35月龄儿童养育照护的效果显示文摘目的 分析儿童早期发展综合干预策略对改善贫困地区0~35月龄儿童早期家庭养育照护的效果.方法 儿童早期发展综合干预项目(IECD)于2014年开始在4个贫困县农村地区试点开展,通过多种途径为项目地区0~35月龄儿童及其看护人提供儿童养育照护多维度综合干预.采用人群干预对照设计,评价干预对看护人健康与心理、儿童营养、早期学习、儿童保护和社会保障等方面的改善效果,分别于2013年和2016年开展基线和中期调查,采用双重差分模型估计干预效果,并控制社会人口学特征等混杂因素.结果 基线调查纳入0~35月龄儿童干预组1 468名、对照组1 485名,中期调查分别纳入1 384名和1 361名.干预组通过2年的干预,看护人抑郁患病率下降9.1%[中期34.8% (479/1 377)比基线43.9% (621/1 414)],对照组下降1.6%[34.3% (464/1 353)比35.9%(509/1 419)],双重差分模型控制因素混杂后,结果显示干预组下降幅度较同期对照组高7.0%(P=0.008);6~23月龄儿童辅食添加频次合格的比例上升10.4%[69.0% (532/771)比58.6%(481/821)],对照组上升幅度2.9%[66.4% (469/706)比63.5%(508/800)],双重差分模型控制混杂因素后,干预组上升幅度比对照组高8.2%(P=0.021);干预组儿童遭受暴力管教的比例下降6.2% [49.1% (478/973)比55.3%(554/1 001)],同期对照组上升4.5%[58.4% (560/959)比53.9%(558/1 036)],双重差分模型控制混杂因素后,两组变化幅度相差11.0%(P=0.001);干预组家庭拥有儿童图书≥3本的比例上升12.7%[42.7% (588/1 378)比30.0% (432/1 440)],同期对照组上升幅度4.2%[25.7% (349/1 357)比21.5%(298/1 388)]双重差分模型控制混杂因素后,干预组比对照组幅度高6.1%(P=0.007).结论 多部门合作儿童早期发展综合干预策略可以有效改善看护人心理状况、促进儿童喂养、支持儿童早期学习,并减少暴力管教等不恰当的养育行为,从而为儿童早期健康发展创造良好养育照护环境.石慧峰 张敬旭 王晓莉 徐媛媛 董胜利 赵春霞 黄小娜 赵颀 陈学锋 周烨 Mayo O'Sullivan Ron Pouwels Robert W.Scherpbier 2018中华儿科杂志2018,56,2:17
2The C-terminal cytoplasmic region of the granulocyte colony-stimulating factor receptor mediates apoptosis in maturation incompetent routine cells显示文摘Dong F pouwel K Hoefsloot HL 1996Exp Hematol1996,24,:1
3Functions of S layers显示文摘Beveridge T J Pouwels P H Sdra M 1997FEMS Microbiol Rev1997,20,:1
4Metabolic alter- ations associated with schizophrenia: a critical evaluation of proton magnetic resonance spectroscopy studies显示文摘Schwerk A Alves FD Pouwels PJ 2014J Neurochem2014,128,1:1
5Increased serum levels of LL37, HMGB1 and S100A9 during exacerbation in COPD patients 显示文摘Pouwels SD Nawijn MC Bathoorn E 2015Eur Respir J2015,45,5:1
6Cloning and expression of a conjugated bile acid hydrolase gene from Lactobacillus plantarum by using a direct plate assay 显示文摘CHRISTIAENS H LEER R J POUWELS P H 1992Appl Environ Microbiol1992,58,12:1
7High-resolution segmented EPI in a motor task fMRI study显示文摘Hoogenraad FG Pouwels PJ Hofman MB 2000Magn Reson Imag2000,18,4:1
8Lactic acid bacteria as antigen delivery vehicles for oral immunization perposes 显示文摘Pouwels PH Leer RJ Shaw M 1998Int J Food Microbiol1998,41,:1
9Identification,cloning and nu- cleotide sequence of a silent S-layer protein gene of Lactobacillus acidophilus ATCC4356 which has extensive similarity with the S-layer Protein gene of this species显示文摘Boot H J Kolen C P A M Pouwels P H 1995J Bacteriol1995,177,:1
10Expression of an Escherichia coli β-galactosidase fusion gene in Aspergillus nidulans显示文摘VAN GORCOM RFM POUWELS PH GOOSEN T 1985Gene1985,40,:1
11Neuronal damage in T1-hypointense multiple sclerosis lesions demonstrated in vivo using proton magnetic resonance spectroscopy 显示文摘van Walderveen MA Barkhof F Pouwels PJ 1999Ann Neurol1999,46,1:1
12Neuronal damage in T1-hypointense multiple sclerosis lesions demonstrated in vivo using proton magnetic resonance spectroscopy显示文摘Van Walderveen MA Bankhof F Pouwels PJ 1999Ann Neurol1999,46,1:1
13Risk of hip/fe-mur fracture after stroke:a population-based case-control study显示文摘POUWELS S LALMOHAMED A LEUFKENS B 2009Stroke2009,40,10:1
14The Potential of Lactobacillus as a Carrier for Oral Immunization:Development and Preliminary Characterization of Vector Systems for Targeted Delivery of Antigen显示文摘PETER H POUWEL ROB J 1996Biotechnology1996,,44:1
15Synergy between dendritic cells and GM- CSF-secreting tumor cells for the treatment of a murine renal cell carcinoma 显示文摘Driessens G Hoffmann P Pouwels M 2009J Immunother2009,32,2:1
16Muscle uridine diphosphate-hexosamines do not decrease despite correction of hyperglycemia-induced insulin resistance in type 2 diabetes显示文摘 Jacobs J R Span P N 2002J Clin Endocrinol Metab2002,87,5:1
17Promotor Analysis and Transcriptional Regulation of Lactobacillus pentosus Genes Involved in Xylose Catabolism显示文摘LOKMAN B C LEER R J POUWELS P H 1994Molecular and General Genetics1994,245,:1
18Cigarette smoke induced DAMP release from necrotic neutrophils triggers pro-inflammatory mediator release显示文摘Heijink IH Pouwels SD Leijendekker C 2015Am J Re- spir Cell Mol Biol2015,52,5:1
19The potential of Lactobacillus as a carrier for oral immunization; development and preliminary characterization of vector systems for targeted delivery of antigens显示文摘 Leer RJ Boersma WJ 1996J Biotechnol1996,44,13:1
20Use of beta-2 agonists and risk of hip/ femur fracture: a population-based case-control study 显示文摘Pouwels S Bracke M 2007Pharmacoepidemiol Drug Saf2007,66,6:1
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