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| 1 | Preventive effect of a pectic polysaccharide of the common cranberry Vaccinium oxycoccos L. on acetic acid-induced colitis in mice显示文摘AIM: To study isolation and chemical characterization of pectin derived from the common cranberry Vaccinium oxycoccos L. (oxycoccusan OP) and the testing of its preventive effect on experimental colitis.METHODS: Mice were administrated orally with OP two days prior to a rectal injection of 5% acetic acid and examined for colonic damage 24 h later. Colonic inflammation was characterized by macroscopical injury and enhanced levels of myeloperoxidase activity measured spectrophotometrically with o-phenylene diamine as the substrate. The mucus contents of the colon were determined by the Alcian blue dye binding method. Vascular permeability was estimated using 4% Evans blue passage after i.p. injection of 0.05 mol/L acetic acid. RESULTS: In the mice treated with OP, colonic macroscopic scores (1.1 ± 0.4 vs 2.7, P < 0.01) and the total square area of damage (10 ± 2 vs 21 ± 7, P < 0.01) were significantly reduced when compared with the vehicle-treated colitis group. OP was shown to decrease the tissue myeloperoxidase activity in colons (42 ± 11 vs 112 ± 40, P < 0.01) and enhance the amount of mucus of colitis mice (0.9 ± 0.1 vs 0.4 ± 0.1, P < 0.01). The level of colonic malondialdehyde was noted to decrease in OP-pretreated mice (3.6 ± 0.7 vs 5.1 ± 0.8, P < 0.01). OP was found to decrease the inflammatory status of mice as was determined by reduction of vascular permeability (161 ± 34 vs 241 ± 21, P < 0.01). Adhesionof peritoneal neutrophils and macrophages was also shown to decrease after administration of OP (141 ± 50 vs 235 ± 37, P < 0.05).CONCLUSION: Thus, a preventive effect of pectin from the common cranberry, namely oxycoccusan OP, on acetic acid-induced colitis in mice was detected. A reduction of neutrophil infiltration and antioxidant action may be implicated in the protective effect of oxycoccusan. | Sergey V Popov Pavel A Markov Ida R Nikitina Sergey Petrishev Vasily Smirnov Yury S Ovodov | 2006 | World Journal of Gastroenterology2006，12，41： | 9 |
| 2 | 氧消耗和二氧化碳恢复期动力学对冠状动脉疾病严重性和结局的预测价值显示文摘血管重塑似乎只对高度缺血的患者有益。该研究调查了在心肺功能运动试验(eardiopulmonary exercisetest,CPET)恢复期中气体分析预测冠状动脉疾病(coronary artery disease,CAD)严重性和预后的价值。方法:研究者研究了40例白人患者(21.2%女性),平均年龄(63.5±7.6)岁,有显著冠状动脉损伤(≥50%)。 | 黄洁 叶鹏 Popovic D Martic D Djordjevic T Pesic V Guazzi M Myers J Mohebi R Arena R | 2017 | 中华高血压杂志2017，25，10： | 5 |
| 3 | Cycle life and utilization studies on cobalt microencapsulated AB5 type metal hydride 显示文摘 | DURAIRAJAN A HARAN B S POPOV B N WHITE R E | 1999 | J Power Sources1999，83，： | 1 |
| 4 | Bow-tie antennas on a dielectric half-space:theory and experiment 显示文摘 | Compton R C McPhedran R C Popovic Z | 1987 | IEEE Transactions on Antennas and Propagation1987，35，6： | 1 |
| 5 | Optimal Controller Designs for Rotating Machines-Penalising the Rate of Change of Control Forcing显示文摘 | Houlston P R Garvey S D Popov A A | 2006 | 7th IFToMM-Conference on Rotor Dynamics Vienna Austria 25 - 28 September 20062006，45，1： | 1 |
| 6 | Antiinflammatory activity of the pectic polysaccharide from Comarum palustre显示文摘 | POPOV S V POPOVA G Y OVODOVA R G | 2005 | Fitoterapia2005，76，34： | 1 |
| 7 | A reliable gait phase detection system 显示文摘 | PAPPAS I P I POPOVIC M R KELLER T | 2001 | IEEE Transactions on Neural Systems and Rehabilitation Engineering2001，9，2： | 1 |
| 8 | Biocatalytic growth of Au nanoparticles:From mechanistic aspects to biosensors design显示文摘 | Zayats M Baron R Popov I | 2005 | Nano Lett2005，5，： | 1 |
| 9 | Electrochemical investi- gations of cobalt-doped LiMn20, as cathode material for lithium-ion batteries显示文摘 | P Arora B N Popov R E White | 1998 | Journal of The Electrochemical Society1998，145，3： | 1 |
| 10 | Luminescent pro-perties of PP and LI)PE films and rods doped with the Eu(111 )-La( HI) complex显示文摘 | Pogreb R Popov O Lirtsman V | 2006 | Polym Adv Technol2006，，3： | 1 |
| 11 | Conformational heterogeneity of the protein-free human spliceosomal U2-U6 snRNA complex显示文摘 | ZHAO C J BACHU R POPOVIC M et ol | 2015 | RNA-A Publication of the RNA Society2015，19，4： | 1 |
| 12 | Electrochemical in vestigations of cobal-dopted LiMn2O4 as cathode material for lithium-ion batteries 显示文摘 | ARIRA P POPOV B N WHITE R E | 1998 | Journal of the Electrochemical Society1998，145，3： | 1 |
| 13 | Gene silencing of IL-12 in dendritic cells inhibits autoimmune arthritis 显示文摘 | Li R Zheng X Popov I | 2012 | J Transl Med2012，10，： | 1 |
| 14 | Longitudinal cracking distress on continuously reinforced concrete pavements in Illinois 显示文摘 | Roesler J R Popovics J S Ranehero J L | 2005 | Journal of Performance of Constructed Facilities2005，19，4： | 1 |
| 15 | Tracking system with five degrees of freedom using a 2d-array of hall sensors and a permanent magnet显示文摘 | Schlageter V Besse P A Popovic R S | 2001 | Sensors and Actuators A-Physical2001，92，13： | 1 |
| 16 | A reliable gait phase detection system显示文摘 | Pappas I P I Popovic M R Keller T | 2001 | IEEE Transactions on Neural Systems and Rehabilitation Engineering2001，9，2： | 1 |
| 17 | High - Precision positioning of a mechanism with nonlinear friction using a fuzzy logic pulse controller显示文摘 | Popovic M R Gorinevsky D M Goldenberg A A | 2000 | Transaction on control system technology2000，8，1： | 1 |
| 18 | Plasma Chemical Vapor Deposition of Thin Carbon Nitride Films Utilizing Transport Reactions 显示文摘 | Plass M F Kassing R | 1999 | Thin Solid Films1999，，： | 1 |
| 19 | Electrochemical investigations of cobalt-doped LiMn2O4 as cathode material for lithium-ion batteries 显示文摘 | Arira P Popov B N White R E | 1998 | J Electrechem Soc1998，145，3： | 1 |
| 20 | Electrochemical investigations of cobalt-doped LiMn2O4 as cathode material for lithium-ion batteries显示文摘 | ARORA P POPOV B N WHITE R E | 1998 | J Electrochem Soc1998，145，3： | 1 |
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