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| 1 | Preventive effect of a pectic polysaccharide of the common cranberry Vaccinium oxycoccos L. on acetic acid-induced colitis in mice显示文摘AIM: To study isolation and chemical characterization of pectin derived from the common cranberry Vaccinium oxycoccos L. (oxycoccusan OP) and the testing of its preventive effect on experimental colitis.METHODS: Mice were administrated orally with OP two days prior to a rectal injection of 5% acetic acid and examined for colonic damage 24 h later. Colonic inflammation was characterized by macroscopical injury and enhanced levels of myeloperoxidase activity measured spectrophotometrically with o-phenylene diamine as the substrate. The mucus contents of the colon were determined by the Alcian blue dye binding method. Vascular permeability was estimated using 4% Evans blue passage after i.p. injection of 0.05 mol/L acetic acid. RESULTS: In the mice treated with OP, colonic macroscopic scores (1.1 ± 0.4 vs 2.7, P < 0.01) and the total square area of damage (10 ± 2 vs 21 ± 7, P < 0.01) were significantly reduced when compared with the vehicle-treated colitis group. OP was shown to decrease the tissue myeloperoxidase activity in colons (42 ± 11 vs 112 ± 40, P < 0.01) and enhance the amount of mucus of colitis mice (0.9 ± 0.1 vs 0.4 ± 0.1, P < 0.01). The level of colonic malondialdehyde was noted to decrease in OP-pretreated mice (3.6 ± 0.7 vs 5.1 ± 0.8, P < 0.01). OP was found to decrease the inflammatory status of mice as was determined by reduction of vascular permeability (161 ± 34 vs 241 ± 21, P < 0.01). Adhesionof peritoneal neutrophils and macrophages was also shown to decrease after administration of OP (141 ± 50 vs 235 ± 37, P < 0.05).CONCLUSION: Thus, a preventive effect of pectin from the common cranberry, namely oxycoccusan OP, on acetic acid-induced colitis in mice was detected. A reduction of neutrophil infiltration and antioxidant action may be implicated in the protective effect of oxycoccusan. | Sergey V Popov Pavel A Markov Ida R Nikitina Sergey Petrishev Vasily Smirnov Yury S Ovodov | 2006 | World Journal of Gastroenterology2006，12，41： | 9 |
| 2 | 热处理对类金刚石碳薄膜力学和摩擦性能的影响显示文摘利用直流磁分离及脉冲阴极双激发源等离子弧薄膜沉积装置制备了含Ti底层和无Ti底层的类金刚石碳薄膜(DLC);采用纳米硬度计、原子力显微镜和X射线光电子能谱仪分析了薄膜的力学性能和结构;采用УСК-1型球-盘滑动摩擦磨损试验机考察了薄膜的摩擦性能.结果表明,同无Ti底层的DLC薄膜相比,含Ti底层的DLC薄膜的硬度和弹性模量较低;含Ti底层的DLC薄膜经真空400℃退火后表面层中存在TiO2,内部存在TiC;而无Ti底层的DLC薄膜经真空500℃退火处理后硬度、弹性模量和表面形貌几乎保持不变;无Ti底层的DLC薄膜经空气中500℃退火后摩擦系数明显降低,这是由于DLC薄膜在空气中热处理时更易发生石墨化所致. | 江晓红 金元生 KAZACHENKO V P POPOV A N ROGACHEV A V | 2004 | 摩擦学学报2004，24，3： | 4 |
| 3 | Predicting the dispersion hardening effect in ferrite-pearlite normalized steels modified with vanadium显示文摘 | Popov V V Goldshteyn M I Akselrod A Y | 1990 | Phys Met & Metall1990，70，1： | 1 |
| 4 | Characterization of sol-gel derived cobalt oxide xerogels as electrochemical capacitor显示文摘 | LIN C RITTER A J POPOV B N | 1998 | Journal of Electrochemical Society1998，145，12： | 1 |
| 5 | Raltitrexed (tomudex) versus standard leucovorin-modulated bolus 5-fluorouracil: results from the randomised phase III Pan-European Trial in Adjuvant Colon Cancer 01 ( PETACC-1 ) 显示文摘 | Popov I Garrato A Sobrero A | 2008 | European Journal of Cancer2008，44，15： | 1 |
| 6 | Increasing the Efficiency of Diamond Edging of Flat Glass 显示文摘 | A V Popov | 2009 | Stekloi Keramika2009，，6： | 1 |
| 7 | Learning physics-based motion style with nonlinear inverse optimization 显示文摘 | Liu C K Hertzmann A Popovic Z | 2005 | ACM Transactions on Graphics2005，24，3： | 1 |
| 8 | Cycle life and utilization studies on cobalt microencapsulated AB5 type metal hydride 显示文摘 | DURAIRAJAN A HARAN B S POPOV B N WHITE R E | 1999 | J Power Sources1999，83，： | 1 |
| 9 | Cognitive performance in asymptomatic patients with advanced carotid disease 显示文摘 | POPOVIC IM LOVRENCIC - HUZJAN A SIMUNDIC AM | 2011 | Cogn Behav Neurol2011，24，3： | 1 |
| 10 | Optimal Controller Designs for Rotating Machines-Penalising the Rate of Change of Control Forcing显示文摘 | Houlston P R Garvey S D Popov A A | 2006 | 7th IFToMM-Conference on Rotor Dynamics Vienna Austria 25 - 28 September 20062006，45，1： | 1 |
| 11 | Features of the magnetoel-Ectric prop-erties of BiFeO3 in high magnetic fields显示文摘 | Popov Y F Kadomtseva A M Krotov S S | 2001 | Low Temp Phys2001，27，6： | 1 |
| 12 | Chemistry of urea nitro derivatives HI Recation of N, N'-dinitrourea with bases显示文摘 | II'yasov S G Lobanova A A Popov N I | 2002 | Russian Journal of Organic Chemistry2002，38，12： | 1 |
| 13 | GH-releasing hormone and TH-releasing peptide-6 for diagnostic testing in GH-deficient adults显示文摘 | Popovic V Leal A Micic D | 2000 | Lancet2000，356，： | 1 |
| 14 | Hepatitis C virus-replicating hepatocytes induce fibrogenic activation of hepatic stellate cells显示文摘 | Schulze-krebs A Premel D Popov Y | 2005 | Gastroenterology2005，129，1： | 1 |
| 15 | Increased expression of the novel proinflammatory cytokine high mobility group box chromosomal protein 1 in skin lesions of patients with lupus erythematosus显示文摘 | Popovic K Ek M Espinosa A | 2005 | Arthritis Rheum2005，52，11： | 1 |
| 16 | Rapidly solidified Fe-TiC composites: Thermodynamics and the peculiarities of microstructure formation in situ显示文摘 | POPOV A A GASIK M M | 1996 | Scripta Materialia1996，35，5： | 1 |
| 17 | Keyframe control of smoke simulations显示文摘 | Treuille A McNamara A PopoviC Z | 2003 | ACM Transactions on Graphics2003，22，3： | 1 |
| 18 | Cognitive performance in asymptomatic patients with advanced carotid disease显示文摘 | Popovic IM Lovrencic-Huzjan A Simundic AM | 2011 | Cogn Behav Neurol2011，24，3： | 1 |
| 19 | Trace and major element pollution originating from coal ash suspension and transport processes显示文摘 | Popovic A Djordjevic D Polic P | 2001 | Environment International2001，26，： | 1 |
| 20 | CD25 and indoleamine 2,3-dioxygenase are up?regulated by prostaglandin E2 and expressed by tumor-associated dendritic cells in vivo: additional mechanisms of T-cell inhibition显示文摘 | VON BERGWELT -BAILDON M S POPOV A SARIC T | 2006 | Blood2006，108，1： | 1 |
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