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| 1 | Confocal laser endomicroscopy and immunoendoscopy for real-time assessment of vascularization in gastrointestinal malignancies显示文摘Gastrointestinal cancers represent a major cause of morbidity and mortality,with incomplete response to chemotherapy in the advanced stages and poor prognosis.Angiogenesis plays a crucial part in tumor growth and metastasis,with most gastrointestinal cancers depending strictly on the development of a new and devoted capillary network.Confocal laser endomicroscopy is a new technology which allows in vivo microscopic analysis of the gastrointestinal mucosa and its microvascularization during ongoing endoscopy by using topically or systemically administered contrast agents.Targeting markers of angiogenesis in association with confocal laser endomicroscopic examination(immunoendoscopy),as a future challenge,will add functional analysis to the morphological aspect of the neoplastic process.This review describes previous experience in endomicroscopic examination of the upper and lower digestive tract with emphasis on vascularization,resulting in a broad spectrum of potential clinical applications,and also preclinical research that could be translated to human studies. | Dan Ionut Gheonea Tatiana Crtnǎ Tudorel Ciurea Carmen Popescu Anca Bǎdǎrǎu Adrian Sǎftoiu | 2011 | World Journal of Gastroenterology2011，17，1： | 6 |
| 2 | 奥马达环素治疗社区获得性细菌性肺炎显示文摘背景及目的澳马达环素(omadacycline)是一种可每日1次静脉或口服给药的新型氨甲基环素类抗生素,在肺组织内的浓度较高,对引起社区获得性细菌性肺炎(CAP)的常见病原体有抗菌活性。 | Stets R Popescu M Gonong JR 牟向东 郭军 | 2019 | 中华结核和呼吸杂志2019，42，12： | 3 |
| 3 | High-resolution impedance mapping using electrically activated quantitative phase imaging显示文摘Retrieving electrical impedance maps at the nanoscale rapidly via nondestructive inspection with a high signal-to-noise ratio is an unmet need,likely to impact various applications from biomedicine to energy conversion.In this study,we develop a multimodal functional imaging instrument that is characterized by the dual capability of impedance mapping and phase quantitation,high spatial resolution,and low temporal noise.To achieve this,we advance a quantitative phase imaging system,referred to as epi-magnified image spatial spectrum microscopy combined with electrical actuation,to provide complementary maps of the optical path and electrical impedance.We demonstrate our system with high-resolution maps of optical path differences and electrical impedance variations that can distinguish nanosized,semi-transparent,structured coatings involving two materials with relatively similar electrical properties.We map heterogeneous interfaces corresponding to an indium tin oxide layer exposed by holes with diameters as small as~550 nm in a titanium(dioxide)over-layer deposited on a glass support.We show that electrical modulation during the phase imaging of a macro-electrode is decisive for retrieving electrical impedance distributions with submicron spatial resolution-and beyond the limitations of electrode-based technologies(surface or scanning technologies).The findings,which are substantiated by a theoretical model that fits the experimental data very well enable achieving electro-optical maps with high spatial and temporal resolutions.The virtues and limitations of the novel optoelectrochemical method that provides grounds for a wider range of electrically modulated optical methods for measuring the electric field locally are critically discussed. | Cristina Polonschii Mihaela Gheorghiu Sorin David Szilveszter Gáspár Sorin Melinte Hassaan Majeed Mikhail E.Kandel Gabriel Popescu Eugen Gheorghiu | 2021 | Light(Science & Applications)2021，10，2： | 2 |
| 4 | Animal models in pressure ulcer research显示文摘 | Salcido R Popescu A | 2007 | J Spinal Cord Med2007，30，2： | 1 |
| 5 | Effects of random heterogeneity of soil properties on bearing capacity 显示文摘 | POPESCU R DEODATIS G NOBAHAR A | 2005 | Probabilist Engrg Mech2005，20，4： | 1 |
| 6 | Seeing the trees in the forest: using lidar and multispectral data fusion with local filtering and variable window size for estimating tree height显示文摘 | POPESCU S C WYNNE R H | 2004 | Photo-grammetric Engineering and Remote Sensing2004，70，5： | 1 |
| 7 | Animal models in pressure ulcer research 显示文摘 | SALCIDO R POPESCU A AHN C | 2007 | J Spinal Cord Med2007，30，2： | 1 |
| 8 | The mean values of liver stiffness assessed by Acoustic Radiation Force Impulse lastongraphy in normal subjects 显示文摘 | Popescu A Sporea I Sirli R | 2011 | Med Ultrason2011，13，1： | 1 |
| 9 | Animal models in pressure ulcer research显示文摘 | Salcido R Popescu A Ahn C | 2007 | J Spinal Cord Med2007，30，2： | 1 |
| 10 | Contrast enhanced ultrasound for the diagnosis of liver hemangiomas in clinical practice显示文摘 | Sirli R Sporea I Popescu A | | 0，，02： | 1 |
| 11 | Geographical and botanical origin discrimi- nation of romanian honey using complex stable isotope data and chemometrics显示文摘 | DINCA O R IONETE R E POPESCU R | 2015 | Food Analyti- cal Methods2015，8，2： | 1 |
| 12 | Evaluation of fully automated motion corrected first pass myocardial perfusion MRI with semi quantitative perfusion parameter maps in patients with ischemic heart disease显示文摘 | Aya Kino Christopher Glielmi Andrada R Popescu | 2012 | Journal of Cardiovascular Magnetic Resonance2012，，： | 1 |
| 13 | Measuring individual tree crown diam- eter with lidar and assessing its influence on estimating forest vol- ume and biomass显示文摘 | Popescu S C Wynne R H | 2003 | Canadian Journal of Remote Sensing2003，29，5： | 1 |
| 14 | Contrast enhanced ultrasound (CEUS) in the evaluation of liver metastases显示文摘 | Danila M Popescu A Sirli R | 2010 | Med Ultrason2010，12，3： | 1 |
| 15 | Animal models in pressure ulcer research显示文摘 | Salcido R Popescu A Ahn C | 2007 | J Spinal Cord Med2007，30，2： | 1 |
| 16 | Estimating plot-level tree heights with liclar:local filtering with a canopy-height based variable win dow size显示文摘 | POPESCU S C WYNNE R H NELSON R F | 2002 | Computers and Electronics in Agriculture2002，37，13： | 1 |
| 17 | Semantics-Based Composition-Oriented Discovery of Web Services显示文摘 | Brogi A Corfini S Popescu R | 2008 | ACM Trans on Interet Technology2008，8，4： | 1 |
| 18 | Contrast enhanced ultrasound(CEUS) in the evaluation of liver metastases显示文摘 | Danila M Popescu A Sirli R | | 0，，03： | 1 |
| 19 | Renal dysfunction associated with liver transplantation显示文摘 | Jindal R M Popescu I | 1995 | Postgrad Med J1995，71，839： | 1 |
| 20 | Kinetics of Cesium and Strontium Ions Removal From Wastewater on Gel and Macroporous Resins显示文摘 | Oancea A M S Popescu A R Radulescu M | 2008 | Solvent Extraction and Ion Exchange2008，26，3： | 1 |
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