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| 1 | 肠道衍生的血清脂多糖与心房颤动患者主要不良心血管事件的风险增加相关:地中海膳食的影响显示文摘肠道微生物群正在成为动脉粥样硬化血栓形成的新型危险因素,但肠道衍生的脂多糖的预测作用尚不清楚。来自意大利罗马Sapienza大学的Pastori等进行了一项前瞻性单中心研究,分析了脂多糖与心房颤动中主要不良心血管事件(major adverse cardiovascular events,MACE)之间的关系,以及坚持地中海膳食(Mediterranean diet,Med-diet)对上述关系的影响。 | 刘莉 叶鹏 Pastori D Carnevale R Nocella C Novo M Santulli M Cammisotto V Menichelli D Pignatelli P Violi F | 2017 | 中华高血压杂志2017，25，9： | 5 |
| 2 | Efficiency of HAART in the prevention of mother to children HIV-1 transmission at Saint Camille medical centre in Burkina Faso,West Africa显示文摘Objective:To evaluate efficiency of HAART in the prevention of mother to child HIV transmission.Methods:A longitudinal study was conducted on 1 300 women attending the antenatal service at Saint Camille Medical Centre from September 2010 to July 2011.The HIV status of mothers was determined by rapid tests and EUSA.Discordant results were confirmed by real-time PCR.PCR was used to determine HIV status of children born from HIV-positive mothers.Results:Among 1 300 pregnant women tested for HIV,378 were seropositive.Mothers were predominantly housewives(69.7%),and their mean age was(28.32±0.15) years.The overall prevalence of HIV transmission from mother to child was 4.8%(18/378).This prevalence differed significantly from 0.0%(0/114) to 6.8%(18/264) in children born from mothers under HAART and those with mothers under New Prophylactic Protocol(ACT + 3TC + NVP),respectively(P< 0.01).Children’s mortality rate during the medical follow up was 1.3%(5/378).Among 16 women with HIV dubious status by ELISA,the Real Time PCR confirmed 2/16(12.5%) as HIV positive. Conclusions:The protocol of prevention of mother to children HIV transmission(PMTCT) is effective.The rate of HIV vertical transmission is significantly reduced.Early diagnosis determined by PCR of children born from HIV- positive mother is necessary and recommended in the context of PMTCT in Burkina Faso.We also found that PCR is an effective tool to confirm HIV status in pregnant women. | Laure Stella Ghoma Linguissi Cyrille Bisseye Tani Sagna Bolni Marius Nagalo Djeneba Ouermi Florencia W Djigma Salvatore Pignatelli Joseph D Sia Virginio Pietra Remy Moret Jean Baptiste Nikiema Jacques Simpore | 2012 | Asian Pacific Journal of Tropical Medicine2012，5，12： | 4 |
| 3 | Antimicrobial resistance of abnormal vaginal discharges microorganisms in Ouagadougou,Burkina Faso显示文摘Objective:To assess the prevalence of bacterial strains and fungal strains infecting the vaginal tract and test their sensitivity to antibiotics in women attending Saint Camille Medical Centre in Ouagadougou.Methods:From January 2008 to December 2009,a total of 2000 vaginal swabs were cultivated for bacterial and fungal identification and isolation.Furthermore,bacterial strains were tested for their susceptibility to several antibiotics used in routine in the centre. Results:The results revealed that microbial isolation and identification was attempted for 1536/2000 sample,a positivity rate of 76.80%.Candida albicans(48.76%),followed by Escherichia coli(16.67%),Streptococcus agalactiae(8-14%) and Staphylococcus aureus(7.55%) were the major agents of genital tract infections in patients.Mycoplasma hominis and Ureaplasma urealyticum combined accounted for less than 7%.Trichomonas vaginalis was identified in 1.04%coses.The antimicrobial tests revealed that the microorganisms developed resistance to several antibiotics including beta lactams.However,antibiotics such as cefamenzol,ciprofloxacin and norfloxacin were still active on these bacteria.Conclusions:The results reveal that many sexually active women are infected by one or more microbial pathogens,probably because of the lock of hygiene or the adoption of some risky behaviors,such as not using condoms or having multiple sexual partners.Efforts should be made to address these points in the country. | Simplice D Karou Florencia Djigma Tani Sagna Christelle Nadembega Moctar Zeba Aboudoulaye Kabre Kokou Anani Djeneba Ouermi Charlemagne Gnoula Virginio Pietra Salvatore Pignatelli Jacques Simpore | 2012 | Asian Pacific Journal of Tropical Biomedicine2012，2，4： | 2 |
| 4 | Amitosis in human adrenal cells显示文摘 | Magalhaes MC Pignatelli D Magalhaes MM | 1991 | Histol Histopathol1991，6，2： | 1 |
| 5 | Loss-offunction mutation in the prokineticin 2 gene causes Kallmann syndrome and normosmic idiopathic hypogo- nadotropic hypogonadism 显示文摘 | PITTELOUD N ZHANG C PIGNATELLI D | 2007 | Proc Natl Acad Sci USA2007，104，17： | 1 |
| 6 | CD40 ligand enhances monocyte tissue factor expression and thrombin generation via oxidative stress in patients with hypercholesterolemia显示文摘 | Sanguigni V Ferro D Pignatelli P | 2005 | Am Coll Cardiol2005，45，1： | 1 |
| 7 | Immediate Antioxidant and Antiplatelet Effect of Atorvastatin via Inhibition of Nox2显示文摘 | Pignatelli P Carnevale R Pastori D | 2012 | Circulation2012，126，1： | 1 |
| 8 | Loss-of-function mutation in the prokineticin 2 gene causes Kallmann syndrome and normosmic idiopathic hypogonadotropic hypogonadism显示文摘 | Pitteloud N Zhang C Pignatelli D | 2007 | Proc Natl Acad Sci U S A2007，104，17： | 1 |
| 9 | Increased superoxide anion production by platelets in hypercholester- olemic patients 显示文摘 | Sanguigni V Pignatelli P Caccese D | 2002 | Thromb Haemost2002，87，5： | 1 |
| 10 | Loss of membranous E-cadherin exprression in pancreatic cancer:correlation with lymph no de metastasis,high grade,and advaneed stage显示文摘 | Pignatelli M Arsari TW Gunter P Liu D Hirano S Takeichi M Kloppel G Lemoine NR | | 0，，： | 1 |
| 11 | Loss-of-function mutation in the prokineticin 2 gene causes Kallmann syn- drome and normosmie idiopathic hypogonadotropie hypogonad- ism显示文摘 | Pitteloud N Zhang C Pignatelli D | 2007 | Proc Natl Acad Sci USA2007，104，17： | 1 |
| 12 | Immunohistochem icai study of heat shock proteins 27, 60 and 70 in the normal human adrenal and in adrenal tumors with suppressed ACTH production 显示文摘 | Pignatelli D Ferreira J Soares P | 2003 | Microsc Rcstech2003，61，3： | 1 |
| 13 | Inadequate anti- coagulation by vitamin K antagonists is associated with major adverse cardiovascular events in patients with atrial fibrillation 显示文摘 | PASTORI D PIGNATELLI P SALIOLA M | 2015 | Int J Cardiol2015，201，15： | 1 |
| 14 | Immediate antioxidant and anti- platelet effect of atorvastatin via inhibition of Nox2 显示文摘 | Pignatelli P Carnevale R Pastofi D | 2012 | Circulation2012，126，1： | 1 |
| 15 | Metformin de- creases platelet superoxide anion production in dia- betic patients显示文摘 | Gargiulo P Caecese D Pignatelli P | 2002 | Diabetes Metab Res Rev2002，18，2： | 1 |
| 16 | Immunohistochemical study of heat shock proteins 27, 60 and'70 in the normal human adrenal and in adrenal tumors with suppressed ACTH production显示文摘 | Pignatelli D Ferreira J Soares P | 2003 | Microsc Res Tech2003，61，3： | 1 |
| 17 | Selective inhibition of neuronal nitric oxide synthesis reduces hyperactivity and increases non-selective attention in the Naples high-excitability rat显示文摘 | Pignatelli M D'Amico F | 2002 | Behav Brain Res2002，130，12： | 1 |
| 18 | Morphoregulatory activities of E-cadherin and beta-I integrins in colorectal tumour cells显示文摘 | Liu D Nasim MM Stamp GWH Hirano S Takeichi M | 1992 | Br Jcancer1992，66，： | 1 |
| 19 | Loss-of-function mutation in the prokineticin 2 gene causes Kallmann syndrome and normosmic idiopathic hypogonadotropic hypogonadism显示文摘 | Pitteloud N Zhang C Pignatelli D | 2007 | Proc Natl Acad Sci U S A2007，104，17： | 1 |
| 20 | Inadequate anticoagulation by Vitamin K Antagonists is associated with Major Adverse Cardiovascular Events in patients with atrial fibrillation显示文摘 | Pastori D Pignatelli P Saiiola M | 2015 | Int J Cardiol2015，201，： | 1 |
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