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13篇 您的检索式:作者名="PHAM DQ"
    题名 作者 年代 出处 被引量
1Inhaled technosphere insulin:a novel delivery system and formulation for the treatment of types 1 and 2 diabetes mellitus显示文摘KUGLER AJ FABBIO KL PHAM DQ 2015Pharmacotherapy2015,35,3:1
2Ranolazine: a novel agent that improves dysfunctional sodium channels 显示文摘Pham DQ Mehta M 2007Int J Clin Pract2007,61,5:1
3Inhaled technosphere insulin:A novel delivery system and formulation for the treatment of types 1 and 2 diabetes mellitus显示文摘Kugler AJ Fabbio KL Pham DQ 2015Pharmacotherapy2015,35,3:1
4Vitamin E supplementation in Alzheimer's disease, Parkinson' s disease, tardive dyskinesia, and cataract 显示文摘Pham DQ Plakogiannis R 2005Ann Pharmacother2005,39,12:1
5Clevidipine for the treatment of severe hypertension in adults 显示文摘NGUYEN HM MA K PHAM DQ 2010Clin Ther2010,32,1:1
6Activated platelet-rich plasma improves adipose-derived stem cell transplantation efficiency in injured articular cartilage显示文摘Van Pham P Bui KH Ngo DQ 2013Stem Cell Res Ther2013,4,4:1
7Rotigotine transdermal system for the treatment of Parkinson's disease 显示文摘Pham DQ Nogid A 2008Clin Ther2008,30,5:1
8Novel CagA ELISA exhibits enhanced sensitivity of Helicobacter pylori CagA antibody显示文摘AIM To develop a novel Helicobacter pylori(H.pylori)CagA antibody enzyme-linked immunosorbent assay(ELISA)suitable for detecting serum anti-CagA antibodies with high sensitivity.METHODS Recombinant East Asian-type CagA protein was purified and immobilized for ELISA.Serum samples from 217Vietnamese individuals(110 H.pylori-infected and107 uninfected individuals)were applied.Conventional ELISA from Western-type CagA and our East Asian-type CagA ELISA were evaluated by comparing 38 subjects with the Western-type genotype and 72 subjects with the East Asian-type cagA genotype.Histological scores of the gastric mucosa were determined using the updated Sydney System to examine the relationship with anti-CagA antibody titers.RESULTS Recombinant 70-100 k Da fragments were immobilized on the ELISA plate.In ROC analysis,the area under the curve of our East Asian-type CagA ELISA was comparable to that of conventional CagA ELISA.The sensitivity of the two ELISAs differed depending on the cagA genotype.The sensitivity of East Asian-type Cag A ELISA was higher for subjects infected with East Asiantype cagA H.pylori(P<0.001),and the sensitivity of the conventional CagA ELISA tended to be higher for subjects infected with Western cagA H.pylori(P=0.056).The titer of anti-CagA antibody tended to correlate with monocyte infiltration scores(r=0.25,P=0.058)and was inversely correlated with H.pylori density(r=-0.26,P=0.043).CONCLUSION The novel ELISA is useful to detect anti-CagA antibodies in East Asian countries,and the titer may be a marker for predicting chronic gastritis.Yuichi Matsuo Yasutoshi Kido Junko Akada Seiji Shiota Tran Thanh Binh Tran Thi Huyen Trang Ho DQ Dung Pham Huu Tung Tran Dinh Tri Ngo P Minh Thuan Le Quang Tam Bui Chi Nam Vu Van Khien Yoshio Yamaoka 2017World Journal of Gastroenterology2017,23,1:1
9Clevidipine for the treatment of se- vere hypertension in adults显示文摘Nguyen HM Ma K Pham DQ 2010Clin Ther2010,32,1:1
10Rotigotine transdermal system for the treatment of parkinson' s disease 显示文摘Pham DQ Nogid A 2008Clinical Therapeutics2008,30,5:1
11Clevidipine for the treatment of severe hypertension in adults 显示文摘Nguyen HM Ma K Pham DQ 2010Clin Ther2010,32,1:1
12Clevidipine for the treat- ment of severe hypertension in adults显示文摘NGUYEN HM MA K PHAM DQ 2010Clin Ther2010,32,1:1
13Clevidipine for the treatment of severe hypertension in adults 显示文摘Nguyen HM Ma K Pham DQ 2010Clin Ther2010,32,1:1
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