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| 1 | Simulation Modeling in Plant Breeding: Principles and Applications显示文摘Conventional plant breeding largely depends on phenotypic selection and breeder's experience, therefore the breeding efficiency is low and the predictions are inaccurate. Along with the fast development in molecular biology and biotechnology, a large amount of biological data is available for genetic studies of important breeding traits in plants, which in turn allows the conduction of genotypic selection in the breeding process. However, gene information has not been effectively used in crop improvement because of the lack of appropriate tools. The simulation approach can utilize the vast and diverse genetic information, predict the cross performance, and compare different selection methods. Thus, the best performing crosses and effective breeding strategies can be identified. QuLine is a computer tool capable of defining a range, from simple to complex genetic models, and simulating breeding processes for developing final advanced lines. On the basis of the results from simulation experiments, breeders can optimize their breeding methodology and greatly improve the breeding efficiency. In this article, the underlying principles of simulation modeling in crop enhancement is initially introduced, following which several applications of QuLine are summarized, by comparing the different selection strategies, the precision parental selection, using known gene information, and the design approach in breeding. Breeding simulation allows the definition of complicated genetic models consisting of multiple alleles, pleiotropy, epistasis, and genes, by environment interaction, and provides a useful tool for breeders, to efficiently use the wide spectrum of genetic data and information available. | WANG Jian-kang Wolfgang H Pfeiffer | 2007 | Agricultural Sciences in China2007，6，8： | 5 |
| 2 | Immunolocalization of H+-ATPase the gill epithelia of rainbow trout显示文摘 | Lin H Pfeiffer D Vogl A Pan J Randall D | 1994 | The Journal of experimental biology1994，195，1： | 1 |
| 3 | General population and medical student perceptions of good and bad doctors in Mozambique 显示文摘 | Pfeiffer A Noden B H Walker Z A | 2011 | Educ Health (Abingdon)2011，24，1： | 1 |
| 4 | Reflective microdisplays for projection or virtual-view applications 显示文摘 | Morrissy J H Pfeiffer M Schott D | 1999 | SID''99Digest1999，30，6： | 1 |
| 5 | Switching from a preserved to a preservative-free prostaglandin preparation in topi- cal glaucoma medication 显示文摘 | UUSITALO H CHEN E PFEIFFER N | 2010 | Acta Ophthalmol2010，88，3： | 1 |
| 6 | Evidence for trans - polyacetylene in nano- crystalline diamond films 显示文摘 | Pfeiffer R Kuzmany H Knoll P | 2003 | Dia- mond & Related Materials2003，12，37： | 1 |
| 7 | AMMI adjustment for statistical analysis of an internal wheat yield trial显示文摘 | CROSSA J Fox P N Pfeiffer W H | 1991 | Theor Appl Genet1991，81，： | 1 |
| 8 | 'Delayed securi- ty price adjustments to financial analysts' forecasts of annual earnings 显示文摘 | Elgers P T May H Lo Pfeiffer R J | 2001 | The Accounting Review2001，28，： | 1 |
| 9 | Presence of urokinase plasminogen activator,its inhibitor and receptor in small cell lung cancer and non-small cell lung cancer显示文摘 | Pappot H Pfeiffer P Grondahlhansen J | | 0，，01： | 1 |
| 10 | Silicium dio- xide nanopartieles as carriers for photoactivatable CO-relea- sing molecules (PbotoCORMs) 显示文摘 | Dordelmann G Pfeiffer H Birkner A | 2011 | Inorg Chem2011，50，： | 1 |
| 11 | Switching from a preservedto a preservative-free prostaglandin preparation in topical glaucomamedication显示文摘 | Uusitalo H Chen E Pfeiffer N | 2010 | Acta Ophthalmol2010，88，3： | 1 |
| 12 | Heteroplasmic substitutions in the mitochondrial DNA control region in mother and child samples显示文摘 | Hühne J Pfeiffer H Brinkmann B | 1998 | Int J Legal Med1998，112，： | 1 |
| 13 | Angiotensin II stimulates matrix metalloproteinase secretion in human vascular smooth muscle cells via nuclear Factor-KB and activator protein 1 in a redox- sensitive manner显示文摘 | Michael Browatzki Dina Larsen Carolein A H Pfeiffer | 2005 | JVR2005，42，4： | 1 |
| 14 | Structure and correlations of the flux line lattice in crystalline Nb through the peak effect显示文摘 | Gammel P L Yaron U Ramirez A P Bishop D J Chang A M Ruel R Pfeiffer L N Bucher E D'Anna G Huse D A Mortensen K Eskildsen M R Kes P H | | 0，，： | 1 |
| 15 | Biofortification of durum wheat with zinc and iron 显示文摘 | Cakmak I Pfeiffer W H McClafferty B | 2010 | Cereal Chemistry2010，87，： | 1 |
| 16 | Assessing children's physical activity in their homes:the observational system for recording physical activity in children-home显示文摘 | Mciver K L Brown W H Pfeiffer K A Dowda M Pate R R | 2009 | Journal of applied behavior analysis2009，42，1： | 1 |
| 17 | The influence of protein intake on water balance, flow rate and apparent digestibility of nutrition at the distalileum in growing pigs显示文摘 | PFEIFFER A HENKELE H VERSTEGEN M A | 1995 | Livestock Product Science1995，44，： | 1 |
| 18 | RET rearrangement in radiation induced papillary thyroid carcinoma: High prevalence of topoisomerase I sites at breakpoints and micro homology mediated end joining in ELE1 and RET chimeric genes 显示文摘 | Klugbauer S Pfeiffer P Cassenhuber H | 2001 | Genomics2001，，： | 1 |
| 19 | A set of SAS macros for calculating and displaying adjusted odds ratios(with confidence intervals) for continuous covariates in logistic B-spline regression models显示文摘 | Gregory M Ulmer H Pfeiffer KP | 2008 | Comput Methods Programs Biomed2008，92，： | 1 |
| 20 | Sodium zirconate CNa,Zr03) as a catalyst in a soybean oil transes?terification reaction for biodiesel production显示文摘 | Santiago-Torres N Romero-Ibarra I Pfeiffer H | 2014 | Fuel Pro?cessing Technology2014，120，： | 1 |
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