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| 1 | Two strategies for prevention of cytomegalovirus infections after liver transplantation显示文摘AIM: To analyze differences in patients' clinical course, we compared two regimes of either preemptive therapy or prophylaxis after liver transplantation.METHODS: This retrospective study was reviewed and approved by the institutional review board of the University of Leipzig. Cytomegalovirus(CMV) prophylaxis with valganciclovir hydrochloride for liver transplant recipients was replaced by a preemptive strategy in October 2009. We retrospectively compared liver transplant recipients 2 years before and after October 2009. During the first period, all patients received valganciclovir daily. During the second period all patients included in the analysis were treated following a preemptive strategy. Outcomes included one year survival and therapeutic intervention due to CMV viremia or infection.RESULTS: Between 2007 and 2010 n = 226 patients underwent liver transplantation in our center. n = 55 patients were D^+/R^- high risk recipients and were excluded from further analysis. A further 43 patients had to be excluded since CMV prophylaxis/preemptive strategy was not followed although there was no clinical reason for the deviation. Of the remaining 128 patients whose data were analyzed, 60 receivedprophylaxis and 68 were treated following a preemptive strategy. The difference in overall mortality was not significant, nor was it significant for one-year mortality where it was 10%(95%CI: 8%-28%, P = 0.31) higher for the preemptive group. No significant differences in blood count abnormalities or the incidence of sepsis and infections were observed other than CMV. In total, 19 patients(14.7%) received ganciclovir due to CMV viremia and/or infections. Patients who were treated according to the preemptive algorithm had a significantly higher rate risk of therapeutic intervention with ganciclovir [n = 16(23.5%) vs n = 3(4.9%), P = 0.003)].CONCLUSION: These data suggest that CMV prophylaxis is superior to a preemptive strategy in patients undergoing liver transplantation. | Philipp Simon Max Sasse Sven Laudi David Petroff Michael Bartels Udo X Kaisers Sven Bercker | 2016 | World Journal of Gastroenterology2016，22，12： | 5 |
| 2 | ASTMF1962-定向钻进铺设聚乙烯管道设计指南简介显示文摘由美国材料与实验协会(AsTM)提出的F1962设计指南-“大型水平定向钻进穿越工程铺设聚乙烯管道设计指南”已成功应用十年,成绩斐然。 | Larry J. Petroff 苏波(译) | 2011 | 非开挖技术2011，，1： | 4 |
| 3 | Ovarian autoimmune disease: clinical concepts and anima models显示文摘卵巢不是一个 immunologically 给予优惠的机关,但是在为卵巢特定的抗原的 tolerogenic 机制的一个故障在生育力上有灾难性的后果在里面女人,和这在自体免疫的疾病的鼠科的模型被复制。孤立的卵巢的自体免疫的疾病在女人是稀罕的,由于疾病和无能到的严厉可能播送越过代授与卵巢的疾病的基因信息。尽管如此,自体免疫的卵巢炎经常与另外的自体免疫的疾病联合被观察,特别地自体免疫的肾的疾病,并且在社会和单个健康上拿使用费。在老鼠的研究揭示了保护卵巢免受自体免疫的攻击的伤害的至少二机制。这些机制为自体免疫的管理者(亚耳河) 由导出胸腺的规章的 T 房间,以及一个角色包括 autoreactive T 房间的控制,在髓的 thymic 导致限制织物的抗原的表示的一个 transcriptional 管理者上皮的房间在 T 房间的开发期间。尽管后者机制不完全地被定义,也的失败导致自体免疫调停指向和卵巢的滤泡的弄空,这很好被建立。在这评论,我们将探讨自体免疫调停的临床的特征和后果在女人的卵巢的不孕,以及由动物揭示了的疾病的可能的机制当模特儿。 | Bryce D Warren William K Kinsey Lynda K McGinnis Lane K Christenson Susmita Jasti Anne M Stevens Brian K Petroff Margaret G Petroff | 2014 | Cellular & Molecular Immunology2014，11，6： | 3 |
| 4 | Homocarnosine and seizure control in juvenile myoclonic epilepsy and complex partial seizures显示文摘 | Petroff O A Hyder F Rothman D L | 2001 | Neurology2001，56，6： | 1 |
| 5 | 显示文摘 | Petroff MG Sedlmayr P Azzola D | 2002 | J Reprod Immunol2002，56，12： | 1 |
| 6 | Thick ceramic coatings using a sol gel based ceramic-ceramic 0 - 3 composite 显示文摘 | Barrow D Petroff T Sayer M | 1995 | Surface and Coatings Technology1995，7677，13： | 1 |
| 7 | Thick ceramic coatings using a Sol-gel based ceramic-ceramic 0-3 composite 显示文摘 | Barrow D A Petroff T E Sayer M | 1995 | Surf Coat Techn1995，7677，11： | 1 |
| 8 | Oscillatory interlayer exchange and magnetoresistance in Fe/Cu multilayers显示文摘 | PETROFF F BARTH(E)LEMY A MOSCA D H | 1991 | Phys Rev B1991，44，10： | 1 |
| 9 | Decidual macrophages are potentially suseptible to inhibition by class I and Ib HLA molecules 显示文摘 | Petroff MG Sedlmayr P Azzola D | 2002 | Reprod Immunol2002，56，12： | 1 |
| 10 | Size quantization effects in InAs self-assembled quantum dots显示文摘 | SCHMIDT K H MEDEIROS-RIBEIRO G GARCIA J PETROFF P M | 1997 | Appl Phys Lett1997，70，： | 1 |
| 11 | Topiramate increases brain GABA,homocarnosine,and pyrrolidinone in patients with epilepsy显示文摘 | Petroff OAC Hyder F Mattson RH | 1999 | Neurology1999，52，： | 1 |
| 12 | Topiramate increases brain GABA, homocarnosine, and pyrrolidinone in patients with epilepsy 显示文摘 | Petroff OA Hyder F Mattson RH Rothman DL | 1999 | Neurology1999，52，3： | 1 |
| 13 | 显示文摘 | Leon R Petroff P M Stucky G D | 1995 | Science1995，268，： | 1 |
| 14 | X-ray Topographic Study of Defects in KH2 PO4 Single Crystals and Their Relation with Impurity Segregation显示文摘 | Belout C Dunla E Petroff J F | 1974 | Journal of Crystal Growth1974，73，： | 1 |
| 15 | Localized 1H NMR measurements of gamma-aminobutyric acid in human brain in vivo显示文摘 | Rothman D L Petroff O A Behar K L | 1993 | Proc Nati Cad Sci USA1993，90，12： | 1 |
| 16 | Angiotensin Ⅱ : a regulator of cardiomyocyte function and survival 显示文摘 | PALOMEQUE J DELBRIDGE L PETROFF M V | 2009 | Front Biosci (Landmark Ed)2009，14，： | 1 |
| 17 | Human brain γ-aminobutyric acid levels and seizure control following initiation of vigabatrin therapy显示文摘 | Petroff O A C Behar K L Mattson R H | 1996 | J Neurochem1996，67，6： | 1 |
| 18 | Uterine leukocytes: key players in pregnancy显示文摘 | Hunt JS Petroff MG Bumett TG | 2000 | Semin Cell Dev BIOL2000，21，： | 1 |
| 19 | HLA-G and immune tolerance in pregnancy 显示文摘 | Hunt JS Petroff MG Mclntire RH | 2005 | FASEB J2005，19，7： | 1 |
| 20 | Isolation and culture of term human trophoblast cells显示文摘 | Petroff MG Phillips TA Ka H | 2006 | Methods Mol Med2006，121，： | 1 |
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