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| 1 | Current surgical strategies for total arthroplasty in valgus knee显示文摘The majority of orthopaedic surgeons even currentlyagree that primary total arthroplasty in valgus knees with a deformity of more than ten degrees may prove challenging. The unique sets of bone and soft tissue abnormalities that must be addressed at the time of the operation make accurate axis restoration, component orientation and joint stability attainment a difficult task. Understanding the specific pathologic anatomic changes associated with the valgus knee is a prerequisite so as to select the proper surgical method, to optimize component position and restore soft-tissue balance. The purpose of this article is to review the valgus knee anatomical variations, to assess the best pre-operative planning and to evaluate how to choose the grade of constraint of the implant. It will also be underlying the up-to-date main approaches and surgical techniques be proposed in the English literature both for bone cuts and soft tissue management of valgus knees. | Dimitrios Nikolopoulos Ioannis Michos George Safos Petros Safos | 2015 | World Journal of Orthopedics2015，6，6： | 20 |
| 2 | Relation between common polymorphisms in genes related to inflammatory response and colorectal cancer显示文摘瞄准:在象 interleukin ( IL )那样的煽动性的反应相关的基因调查在普通单个核苷酸多型性( SNP )之间的协会-6, IL-8 ,肿瘤坏死因素高山哈( TNFalpha ), peroxisome 激活proliferators 的受体鲸鱼群妈( PPARgamma ),细胞间的粘附 molecule-1 ( ICAM-1 )和颜色的风险在一组希腊病人的表面的癌症( CRC )。方法:学习组由 222 个 CRC 病人和 200 健康控制组成了。Genotyping 用 PRC-RFLP 的等位基因特定的 PCR 被执行,结果被定序证实。我们在 IL-6 学习了 SNP 的协会(-174G>C), IL-8 (-251T>A), TNFalpha (-308G>A), ICAM-1 (R241G 和 K469E ) ,和 PPARgamma (Pro12Ala ) 基因和 CRC 的风险。结果:ICAM-1 的 IL-6 -174G, R241 和 K469 等位基因与 CRC 的增加的风险被联系(或 = 1.77, 95% CI:1.34-2.34;或 = 1.83, 95% CI:1.23-2.72;并且或 = 1.35, 95% CI:1.03-1.77 分别地) 。IL-8 和 TNFalpha 多型性没有效果。而 PPARgamma Pro12 遗传型与疾病的增加的风险被联系(或 = 1.78, 95% CI:1.25-2.49 ) 。结论:在在免疫逻辑的普通 SNP 之间的协会反应相关的基因和 CRC 在现在的学习被报导。除了使恶意开始和前进的机制清楚些, SNP 可以改进在风险的为亚人口的适当屏蔽。 | George Theodoropoulos Ioannis Papaconstantinou Evangelos Felekouras Nikolaos Nikiteas Petros Karakitsos Dimitris Panoussopoulos Andreas Ch Lazaris Efstratios Patsouris John Bramis Maria Gazouli | 2006 | World Journal of Gastroenterology2006，12，31： | 16 |
| 3 | 多样化与集中化——放松管制的大众传媒领域显示文摘新媒体的市场竞争带来媒介多样性 ,同时导致媒介所有权的集中化。这种多样性更多地表现为频道数量上的增加 ,而非实质内容的丰富。而媒体所有权的集中 ,虽然保证了媒介参与国际竞争的实力和获得规模经济效益 ,但也导致了人们一味地对利益的追逐。如何真正保证文化质量 。 | Petros Iosifides 郭丽萍 | 2000 | 国际新闻界2000，22，5： | 14 |
| 4 | Factors affecting breastfeeding duration in Greece:What is important?显示文摘AIM:To investigate factors associated with breastfeeding duration(BD) in a sample of mothers living in Greece.METHODS:Four hundred and twenty-eight mothers(438 infants) were initially recruited in a tertiary University Hospital.Monthly telephone interviews(1665in total) using a structured questionnaire(one for each infant) were conducted until the sixth postpartum month.Cox regression analysis was used to assess factors influencing any BD.RESULTS:Any breastfeeding rates in the first,third,and sixth month of the infant's life reached 87.5%,57.0%and 38.75%,respectively.In the multivariate analysis,maternal smoking in the lactation period[hazard-ratio(HR) = 4.20]and psychological status(HR = 1.72),and the introduction of a pacifier(HR =2.08),were inversely associated,while higher maternal education(HR_(university/college vs primary/high school) = 0.53,HR_(master's vs primary/high school) = 0.20),and being an immigrant(HR = 0.35) were positively associated with BD.CONCLUSION:Public health interventions should focus on campaigns against smoking during lactation,target women of lower educational status,and endorse the delayed introduction of pacifiers. | Evangelia-Filothei Tavoulari Vassiliki Benetou Petros V Vlastarakos Theodora Psaltopoulou George Chrousos George Kreatsas Alexandras Gryparis Athena Linos | 2016 | World Journal of Clinical Pediatrics2016，5，3： | 12 |
| 5 | Liver transplantation and non-alcoholic fatty liver disease显示文摘Non-alcoholic fatty liver disease(NAFLD) is an important health problem worldwide. NAFLD encompasses a histological spectrum ranging from bland liver steatosis to severe steatohepatitis(nonalcoholic steatohepatitis, NASH) with the potential of progressing to cirrhosis and its associated morbidity and mortality. NAFLD is thought to be the hepatic manifestation of insulin resistance(or the metabolic syndrome); its prevalence is increasing worldwide in parallel with the obesity epidemic. In many developed countries, NAFLD is the most common cause of liver disease and NASH related cirrhosis is currently the third most common indication for liver transplantation. NASH related cirrhosis is anticipated to become the leading indication for liver transplantation within the next one or two decades. In this review, we discuss how liver transplantation is affected by NAFLD, specifically the following:(1) the increasing need for liver transplantation due to NASH;(2) the impact of the increasing prevalence of NAFLD in the general population on the quality of deceased and live donor livers available for transplantation;(3) the long term graft and patient outcomes after liver transplantation forNASH,and finally;and(4)the de novo occurrence of NAFLD/NASH after liver transplantation and its impact on graft and patient outcomes. | Petros Zezos Eberhard L Renner | 2014 | World Journal of Gastroenterology2014，20，42： | 12 |
| 6 | Cytopathologic diagnosis of fine needle aspiration biopsies of thyroid nodules显示文摘Fine-needle aspiration(FNA) cytology is an important diagnostic tool in patients with thyroid lesions.Several systems have been proposed for the cyropathologic diagnosis of the thyroid nodules.However cases with indeterminate cytological findings still remain a matter of debate.In this review we analyze all literature regarding Thyroid Cytopathology Reporting systems trying to identify the most suitable methodology to use in clinical practice for the preoperative diagnosis of thyroid nodules.A review of the English literature was conducted,and data were analyzed and summarized and integrated from the authors' perspective.The main purpose of thyroid FNA is to identify patients with higher risk for malignancy,and to prevent unnecessary surgeries for benign conditions.The Bethesda System for Reporting Thyroid Cytopathology is the most widely used system for the diagnosis of thyroid FNA specimens.This system also contains guidelines for the diagnosis and treatment of indeterminate or suspicious for malignancy cases.In conclusion,patients who require repeated FNAs for indeterminate diagnoses will be resolved by repeat FNA in a percentage of 72%-80%. | Evangelos P Misiakos Niki Margari Christos Meristoudis Nickolas Machairas Dimitrios Schizas Konstantinos Petropoulos Aris Spathis Petros Karakitsos Anastasios Machairas | 2016 | World Journal of Clinical Cases2016，4，2： | 12 |
| 7 | Inflammatory bowel disease and thromboembolism显示文摘Patients with inflammatory bowel disease(IBD) have an increased risk of vascular complications. Thromboembolic complications,both venous and arterial,are serious extraintestinal manifestations complicating the course of IBD and can lead to significant morbidity and mortality. Patients with IBD are more prone to Thromboembolic complications and IBD per se is a risk factor for thromboembolic disease. Data suggest that thrombosis is a specific feature of IBD that can be involved in both the occurrence of thromboembolic events and the pathogenesis of the disease. The exact etiology for this special association between IBD and thromboembolism is as yet unknown,but it is thought that multiple acquired and inherited factors are interacting and producing the increased tendency for thrombosis in the local intestinal microvasculature,as well as in the systemic circulation. Clinicians' awareness of the risks,and their ability to promptly diagnose and manage TEs are of vital importance. In this review we discuss how thromboembolic disease is related to IBD,specifically focusing on:(1) the epidemiology and clinical features of thromboembolic complications in IBD;(2) the pathophysiology of thrombosis in IBD;and(3) strategies for the prevention and management of thromboembolic complications in IBD patients. | Petros Zezos Georgios Kouklakis Fred Saibil | 2014 | World Journal of Gastroenterology2014，20，38： | 12 |
| 8 | Wireless capsule endoscopy in the investigation of patients with chronic renal failure and obscure gastrointestinal bleeding (preliminary data)显示文摘瞄准:在小肠(SB ) 的察觉调查无线的囊内视镜检查法(WCE ) 的角色在有长期的肾衰竭(CRF ) 并且阴暗流血的病人的病理。方法:有阴暗流血的连续 CRF 病人有希望地被学习。有正常肾的功能并且阴暗流血的病人,与 WCE 在一样的时期期间调查了,被用于结果的解释。结果:十七个 CRF 病人(11 公开, 6 玄术流血) 并且 51 个病人(33 公开, 18 玄术流血) 与正常,肾的功能在这研究被注册。积极 SB 调查结果在 70.6% CRF 病人被检测(P <
0.05 ) 。SB angiodysplasia 在 47% CRF 病人被识别。Univariate 逻辑回归为 angiodysplasia 作为一个重要预兆的因素揭示了 CRF (P <
0.05 ) 。治疗学的措施与积极调查结果在 66% 病人被承担。结论:根据我们的初步的结果, SB angiodysplasia 与阴暗流血在 CRF 病人之中在增加的流行被发现。WCE 在胃肠的病理的诊断并且在计划适当治疗学的干预是有用的并且因此,应该在这组病人的病情的检查被包括。 | Stephanos Karagiannis Spyros Goulas Georgios Kosmadakis Petros Galanis Dimitrios Arvanitis John Boletis Evangelos Georgiou Christos Mavrogiannis | 2006 | World Journal of Gastroenterology2006，12，32： | 8 |
| 9 | Retinol-binding protein, acute phase reactants and Helicobacter pylori infection in patients with gastric adenocarcinoma显示文摘AIM: To determine the serum levels of c-reactive protein (CRP), transferrin (TRF), a2-macroglobulin (A2M),ceruloplasmin (CER), a1-acid glycoprotein (AAG), prealbumin (P-ALB) and retinol-binding protein (RBP) in gastric carcinoma patients and to explore their possible correlation with underlying Helicobacter pylori (H pylon)infection.METHODS: We measured the serum levels of CRP, TRF,A2M, CER, AAG, P-ALB, and RBP in 153 preoperative patients (93 males; mean age: 63.1±11.3 years) with non-cardia gastric adenocarcinoma and 19 healthy subjects.RESULTS: The levels of CRP, CER, RBP, andAAG in cancer patients were significantly higher than those in healthy controls (P<0.0001), while no difference was found regarding the TRF, P-ALB, and A2M levels. Cancer patients with H pylori infection had significantly lower RBP values compared to non-infected ones (P<0.0001)and also higher values of CRP and AAG (P = 0.09 and P = 0.08, respectively).CONCLUSION: High serum levels of CRP, CER and AAG in cancer patients do not seem to be related to H pylori infection. Retinol-binding protein seems to discriminate between infected and non-infected patients with gastric carcinoma. Further studies are needed to explore if it is directly involved in the pathogenesis of the disease or is merely an epiphenomenon. | Nicolas Tsavaris Christos Kosmas Petros Kopterides Dimitrios Tsikalakis Hlias Skopelitis Fotini Sakelaridi Nikitas Papadoniou Michalis Tzivras Vasilios Balatsos Christos Koufos Athanasios Archimandritis | 2005 | World Journal of Gastroenterology2005，11，45： | 7 |
| 10 | Postoperative jaundice after cardiac surgery显示文摘BACKGROUND:The frequency and pattern of hyperbili-rubinemia after open-heart surgery and its severe perioperative complications are not well clarified. The purpose of this study was to investigate the incidence and nature of postoperative jaundice in patients undergoing cardiac operation,to analyze the determinants,and to identify the clinical significance of this complication with regard to the associated morbidity and mortality. METHODS:A prospective observational study was made during the period of 2003-2004 in a Surgical Intensive Care Unit of a Cardiac Surgery Center,Athens. One hundred twenty-eight adult patients for open heart surgery were divided into three groups. Group A included 50 patients who underwent coronary artery bypass crafting(CABG),group B 31 patients who were subjected to aortic valve replacement(AVR)+CABG and group C 47 patients who underwent mitral valve replacement(MVR)+CABG. Aminotransferases,alkaline phosphatase,gamma-glutamyl-transpeptidase and both types of bilirubin were determined at admission,24 hours after the operation and thereafter according to clinical evolution. The presence of jaundice was associated with elevated serum bilirubin above 3 mg/dl. RESULTS:Hyperbilirubinemia developed in 34 patients(26.5%). The incidence of postoperative jaundice was higher in patients who were subjected to MVR+CABG than to CABG and AVR+CABG. Hyperbilirubinemia was correlated with prolonged cardiopulmonary by-passtime(P<0.001),aortic cross-clamping time(P<0.001),the use of intra aortic balloon pumping(P<0.001),the administration of inotrops and the number of blood and plasma transfusions. Postoperative jaundice resulted mainly from an increase in conjugated bilirubin. CONCLUSIONS:Although hyperbilirubinemia seems to be multifactorial,the type of operation,the preoperative hepatic dysfunction due to advanced heart failure(NYHA Ⅱ-Ⅲ) and the decreased hepatic flow during the operation seem to determine the incidence of jaundice. | Aikaterini Mastoraki Emmanouil Karatzis Sotiria Mastoraki Ioannis Kriaras Petros Sfirakis Stefanos Geroulanos | 2007 | Hepatobiliary & Pancreatic Diseases International2007，6，4： | 7 |
| 11 | Managing high risk glaucoma with the Ahmed valve implant:20 years of experience显示文摘AIM: To estimate the efficacy and safety of the Ahmed implant in patients with high risk for failure after glaucoma surgery.METHODS: In 342 eyes of 342 patients with refractory glaucoma, even with application of medical treatment, the Ahmed valve was introduced for intraocular pressure(IOP) control, in the period of the last 20y. The nature of glaucoma was neovascular in 162 eyes, pseudophakic or aphakic in 49 eyes, inflammatory in 29 eyes and non working previous antiglaucomatic surgical interventions in 102 eyes. RESULTS: Follow-up ranged from 18 to 120m o with a mean follow-up of 63.2m o. IOP before the operation decreased from 31.6±10.4 mmHg to 18.3±5.4 mm Hg(no systemic treatment) at the end of follow up period. When we compared the IOP values before the operation using ANOVA showed statistically significant difference(P<0.001). The success rate was 85.2% during the first semester, 76.8% at 12 mo and 50.3% at the end of follow up period(18 to 120 mo after implantation). Success rate was 25.7% in neovascular glaucoma, 63.2% in aphakic glaucoma and 73.8% in non working previous antiglaucomatic surgical interventions. Complications due to the implant were: serous choroidal detachment in 14.8%, blockage of the tube in 2.8%, malposition of the tube in 4.9%, suprachoroidal hemorrhage in 2.1%, cataract progression in 39.6%(phakic eyes), shallow anterior chamber in 9.2%, hyphaema in 28.9%, exposure of valve in 2.6%, exposure of tube in 9.3%, hypotony in 4.9% and conjunctival fibrosis in 41.5%.CONCLUSION: Despite the fact that Ahmed valve implant had suchlike results as other implants concerning the IOP control, complications rate due to hypotony or over filtration in the first days after the intervention are not that frequent as with other valve implants. | tryfon rotsos anastasia tsioga konstantinos andreanos andreas diagourtas petros petrou ilias georgalas dimitrios papaconstantinou | 2018 | International Journal of Ophthalmology(English edition)2018，11，2： | 5 |
| 12 | Totally laparoscopic left hepatectomy using the Torsional Ultrasonic Scalpel显示文摘Minimal invasive techniques have allowed for major surgical advances.We report our initial experience of performing total laparoscopic left hepatectomy(segmentsⅡ-Ⅳ)with the Lotus(laparoscopic operation by torsional ultrasound)Ultrasonic Scalpel.The perioperative and postoperative courses of the young female patient were uneventful and she is in a good general condition without complaints 18 mo after surgery.To the best of our knowledge,this is the first total laparoscopic hemihepatectomy to be performed in Greece,as well as the first laparoscopic liver resection using Lotus shears. | Georgios C Sotiropoulos Paraskevas Stamopoulos Petros Charalampoudis Ernesto P Molmenti Athanasios Voutsarakis Gregory Kouraklis | 2013 | World Journal of Gastroenterology2013，19，35： | 5 |
| 13 | Effect of storage temperature and osmotic pre-treatment with alternative solutes on the shelf-life of gilthead seabream(Sparus aurata)fillets显示文摘The objective of the study was the kinetic modelling of the shelf-life of osmotically pre-treated fish during refrigerated and super-chilled storage.Fresh gilthead seabream(Sparus aurata)fillets were treated for 0-360 min at 15℃ in osmotic solutions 50:5 high dextrose equivalent maltodextrin:NaCl/100 g(HDM),40:10:5 HDM:trehalose:NaCl/100 g(HDM+treh)and 40:10:5 HDM:glucosamine:NaCl/100 g(HDM+gluc).Water loss,solid gain,salt content and water activity were monitored throughout treatment.Slices untreated and osmotically pre-treated for 45 min were aerobically packed and stored isothermally at 15,10,5,2.5,0,-1 and -3℃.Quality assessment was based on microbial growth(total viable count,Pseudomonas spp.,Brochothrix thermosphacta,Enterobacteriaceae spp.,H_(2)S-producing bacteria,lactic acid bacteria,yeasts and moulds),total volatile nitrogen(TVB-N),lipid oxidation(TBARs)and sensory scoring.Quality indices were kinetically modelled and temperature dependence of quality loss rates was modelled by Ratkowsky equation.Osmotic pre-treatment led to significant shelf-life extension of fillets,in terms of microbial growth,chemical changes and organoleptic deterioration.The pre-treatment with the alternative solutes led to depression of the freezing point(-1.8,-2.6,-3.2 and-3.5℃ for the untreated samples and the osmotically pre-treated with HDM,HDM t treh and HDM t gluc,respectively).TVB-N values were higher in untreated samples,followed by osmotically treated fillets,mainly at higher storage temperatures(i.e.10 and 15℃).Based on the mathematical models for sensory evaluation scoring,the shelf-life was 12,19,22 and 22 days at 0℃ for untreated and osmotically pre-treated with HDM,HDM t treh and HDM t gluc fish slices,respectively,while the respective values at -3℃ were 21,35,38 and 38 days.The alternative solutes had no significant effect on the quality and shelf-life of pre-treated fish fillet during storage at refrigerated conditions. | Theofania N.Tsironi Petros S.Taoukis | 2017 | Aquaculture and Fisheries2017，2，1： | 5 |
| 14 | Integrating TYMS, KRAS and BRAF testing in patients with metastatic colorectal cancer显示文摘AIM To investigate the impact of thymidylate synthase(TYMS), KRAS and BRAF in the survival of metastatic colorectal cancer(m CRC) patients treated with chemotherapy. METHODS Clinical data were collected retrospectively from records of consecutive patients with m CRC treated with fluoropyrimidine-based chemotherapy from 1/2005 to 1/2007. Formalin-fixed paraffin-embedded tissues were retrieved for analysis. TYMS genotypes were identified with restriction fragment analysis PCR, while KRAS and BRAF mutation status was evaluated using real-time PCR assays. TYMS gene polymorphisms of each of the 3' untranslated region(UTR) and 5'UTR were classified into three groups according to the probability they have for high, medium and low TYMS expression(and similar levels of risk) based on evidence from previous studies. Univariate and multivariate survival analyses were performed.RESULTS The analysis recovered 89 patients with m CRC(46.1% de novo metastatic disease and 53.9% relapsed). Of these, 46 patients(51.7%) had colon cancer and 43(48.3%) rectal cancer as primary. All patients were treated with fluoropyrimidine-based chemotherapy(5FU or capecitabine) as single-agent or in combination with irinotecan or/and oxaliplatin or/and bevacizumab. With a median follow-up time of 14.8 mo(range 0-119.8), 85 patients(95.5%) experienced disease progression, and 63 deaths(70.8%) were recorded. The 3-year and 5-year OS rate was 25.4% and 7.7% while the 3-year progression-free survival rate was 7.1%. Multivariate analysis of TYMS polymorphisms, KRAS and BRAF with clinicopathological parameters indicated that TYMS 3'UTR polymorphisms are associated with risk for disease progression and death(P < 0.05 and P < 0.03 respectively). When compared to tumors without any del allele(genotypes ins/ins and ins/loss of heterozygosity(LOH) linked with high TYMS expression) tumors with del/del genotype(low expression group) and tumors with ins/del or del/LOH(intermediate expression group) have lower risk for disease progression(HR = 0.432, 95%CI: 0.198-0.946, P < 0.04 and HR = 0.513, 95%CI: 0.287-0.919, P < 0.03 respectively) and death(HR = 0.366, 95%CI: 0.162-0.827, P < 0.02 and HR = 0.559, 95%CI: 0.309-1.113, P < 0.06 respectively). Additionally,KRAS mutation was associated independently with the risk of disease progression(HR = 1.600, 95%CI: 1.011-2.531, P < 0.05). The addition of irinotecan in 1st line chemotherapy was associated independently with lower risk for disease progression and death(HR = 0.600, 95%CI: 0.372-0.969, P < 0.04 and HR = 0.352, 95%CI: 0.164-0.757, P < 0.01 respectively).CONCLUSION The TYMS genotypes ins/ins and ins/LOH associate with worst prognosis in m CRC patients under fluoropyrimidine-based chemotherapy. Large prospective studies are needed for validation of our findings. | Anastasios Ntavatzikos Aris Spathis Paul Patapis Nikolaos Machairas George Peros Stefanos Konstantoudakis Danai Leventakou Ioannis G Panayiotides Petros Karakitsos Anna Koumarianou | 2017 | World Journal of Gastroenterology2017，23，32： | 4 |
| 15 | Elevated plasma von Willebrand factor levels in patients with active ulcerative colitis reflect endothelial perturbation due to systemic inflammation显示文摘AIM: To evaluate the plasma von Willebrand factor (vWF) levels in patients with ulcerative colitis (UC) and to investigate their relationship with disease activity,systemic inflammation and coagulation activation.METHODS: In 46 patients with ulcerative colitis (active in 34 patients), clinical data were gathered and plasma vWF levels, markers of inflammation (ESR, CRP, and fibrinogen) and thrombin generation (TAT, F1+2, and D-dimers) were measured at baseline and after 12 wk of treatment. Plasma vWF levels were also determined in 52 healthy controls (HC). The relationship of plasma vWF levels with disease activity, disease extent, response to therapy, acute-phase reactants (APRs) and coagulation markers (COAGs) was assessed.RESULTS: The mean plasma vWF concentrations were significantly higher in active UC patients (143.38±63.73%) than in HC (100.75±29.65%, P = 0.001)and inactive UC patients (98.92±43.6%, P = 0.031).ESR, CRP and fibrinogen mean levels were significantly higher in active UC patients than in inactive UC patients,whereas there were no significant differences in plasma levels of D-dimers, F1+2, and TAT. UC patients with raised APRs had significantly higher mean plasma vWF levels than those with normal APRs (144.3% vs 96.2%,P = 0.019), regardless of disease activity. Although the mean plasma vWF levels were higher in UC patients with raised COAGs than in those with normal COAGs,irrespective of disease activity, the difference was not significant (141.3% vs 118.2%, P = 0.216). No correlation was noted between plasma vWF levels and disease extent. After 12 wk of treatment, significant decreases of fibrinogen, ESR, F1+2, D-dimers and vWF levels were noted only in UC patients with clinical and endoscopic improvement.CONCLUSION: Our data indicate that increased plasma vWF levels correlate with active ulcerative colitis and increased acute-phase proteins. Elevated plasma vWF levels in ulcerative colitis possibly reflect an acutephase response of the perturbed endothelium due to inflammation. In UC patients, plasma vWF levels may be another useful marker of disease activity or response to therapy. | Petros Zezos Georgia Papaioannou Nikolaos Nikolaidis Themistoclis Vasiliadis Olga Giouleme Nikolaos Evgenidis | 2005 | World Journal of Gastroenterology2005，11，48： | 4 |
| 16 | Indications,limitations and maneuvers to enable extended hepatectomy:Current trends显示文摘The liver is a solid organ with a wide variety of primary benign or malignant tumors as well as metastatic lesions.Surgical resection of these tumors remains the only curative modality.Several limitations,however,do not allow the performance of these operations.This review evaluates the indications and limitations regarding these extended hepatic resections,as well as describing all the manipulations that increase the candidates for such operations.A thorough review of the literature was performed in order to define indications for extended hepatectomy,as well as to present all methods that contribute to increasing the volume of the future remnant liver.The role of portal vein ligation,portal vein embolization,two-stage hepatectomy,and in situ liver transection are evaluated in the setting of indications and results.Extended hepatectomies are a necessity due to oncological reasons.All methods developed in order to increase the volume of the remnant liver are safe and efficient.in situ liver transection is a novel and revolutionary two-step procedure for extended hepatic resections.Further clinical studies are required to estimate long-term results and the oncological basis of this technique. | Dimitrios Dimitroulis Petros Tsaparas Serena Valsami Dimitrios Mantas Eleftherios Spartalis Charalampos Markakis Gregory Kouraklis | 2014 | World Journal of Gastroenterology2014，20，24： | 4 |
| 17 | 股骨近端同种异体骨移植治疗全髋关节置换术后VancouverB3型股骨假体周围骨折手术技术显示文摘背景:全髋关节置换术后的股骨假体周围骨折的发生率日益增高,当股骨近端骨量不足并出现骨折时,能够选择的翻修手术方法则不多,其中一种方法就是股骨近端同种异体骨移植术。方法:我们回顾性评估采用股骨近端同种异体骨移植术治疗24例VancouverB,型假体周围骨折患者(25髋)的随访结果和并发症,平均随访时间为5.1年,临床效果采用Harris评分,放射学评估指标包括转子的融合程度、宿主骨和移植骨的融合程度、是否出现移植骨的吸收、是否出现假体的松动或断裂,以须行清除移植骨的翻修手术作为失败的标准。 | Catherine F. Kellett Petros J. Boscainos Anthony C. Maury Ari Pressman Barry Cayen Paul Zalzal David Backstein Allan Gross 史占军(译) 郭予立(译) | 2008 | 中华骨科杂志2008，28，3： | 4 |
| 18 | Hurdle technology for fish preservation显示文摘Fresh fish is a highly perishable product due to the chemical composition of fish flesh and the high microbial load on fish surface.The natural microflora that is more adopted to low temperatures results also in lower thermal bacterial shock from natural temperature to the preservation temperature range.The development of new fish processing(e.g.high hydrostatic pressure,osmotic dehydration,high-intensity pulsed light)and packaging(e.g.modified atmospheres,active and intelligent packaging)methods or novel combinations of existing technologies is sought by the industry in the pursuit of producing alternative products,achieving shelf life extension,and management and reducing food waste.In 2014,processed fish was among the most active new product categories.The lack of dissemination of validated laboratory results for the seafood industry is one of the major issues preventing the uptake of minimal and nonthermal processing for fresh fish.However,it has been reported that some bacteria become more resistant under stress(e.g.psychrotolerant lactobacilli).At the same time,the application of some processing methods(e.g.thermal processing)may affect significantly the nutritional and sensory profile of the target food product.The application of several“soft hurdles”may reduce the rate of fish deterioration and spoilage caused by microbial growth.The objective of this article is to review the preservative effect of alternative hurdles on fish quality and shelf life,focusing on recent,combined applications. | Theofania Tsironi Dimitra Houhoula Petros Taoukis | 2020 | Aquaculture and Fisheries2020，5，2： | 4 |
| 19 | Effects of chromium on activated sludge and on the performance of wastewater treatment plants: A review显示文摘 | Eleni Vaiopoulou Petros Gikas | 2011 | Water Research2011，，3： | 3 |
| 20 | Asymptomatic early acute appendicitis initiated and diagnosed during colonoscopy: A case report显示文摘Colonoscopic diagnosis of asymptomatic early acute appendicitis is exceedingly rare. Although obstruction of the lumen due to various causes is believed to be the most common physiologic mechanism of acute appendicitis, all of the previously documented cases in the literature have only shown a patent appendiceal lumen with pus flowing into the cecum. We present the case of a patient undergoing colonoscopy for colorectal cancer evaluation with no abdominal symptoms. An obstructed, swollen appendix was seen. The process was probably initiated during the colonoscopy, documenting perhaps the earliest stage of acute appendicitis for the first time. Endoscopic, CT and microscopic documentation of the case is also presented. | Michelle Petro Anil Minocha | 2005 | World Journal of Gastroenterology2005，11，34： | 3 |
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