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| 1 | Cervical cancer screening in developing countries at a crossroad:Emerging technologies and policy choices显示文摘Cervical cancer(CC) represents the fourth most common malignancy affecting women all over the world and is the second most common in developing areas. In these areas,the burden from disease remains important because of the difficulty in implementing cytology-based screening programmes. The main obstacles inherent to these countries are poverty and a lack of healthcare infrastructures and trained practitioners. With the availability of new technologies,researchers have attempted to find new strategies that are adapted to low- and middle-income countries(LMIC) to promote early diagnosis of cervical pathology. Current evidence suggests that human papillomavirus(HPV) testing is more effective than cytology for CC screening. Therefore,highly sensitive tests have now been developed for primary screening. Rapid molecular methods for detecting HPV DNA have only recently been commercially available. This constitutes a milestone in CC screening in low-resource settings because it may help overcome the great majority of obstacles inherent to previous screening programmes. Despite several advantages,HPV-based screening has a low positive predictive value for CC,so that HPVpositive women need to be triaged with further testing to determine optimal management. Visual inspection tests,cytology and novel biomarkers are some options. In this review,we provide an overview of current and emerging screening approaches for CC. In particular,we discuss the challenge of implementing an efficient cervical screening adapted to LMIC and the opportunity to introduce primary HPV-based screening with the availability of point-of-care(POC) HPV testing. The most adapted screening strategy to LMIC is still a work in progress,but we have reasons to believe that POC HPV testing makes part of the future strategies in association with a triage test that still needs to be defined. | Rosa Catarino Patrick Petignat Gabriel Dongui Pierre Vassilakos | 2015 | World Journal of Clinical Oncology2015，6，6： | 16 |
| 2 | Diagnosis and management of cervical cancer 显示文摘 | Petignat P Roy M | 2007 | BMJ2007，335，7623： | 1 |
| 3 | Age-related performance of human papillomavirus testing used as an adjunct cytology for cervical carcinoma screening in a population with a low incidence of cervical carcinoma显示文摘 | Petignat P Faltin D Goffin F | 2005 | Cancer Cytopatho12005，105，： | 1 |
| 4 | Prengnancy in a cesarean scar显示文摘 | Vial Y Petignat P Hohlfeld P | 2000 | Ultrasound Obstet Gynecol2000，16，： | 1 |
| 5 | Pregnancy in a cesarean scar 显示文摘 | Viall Y Petignat P Hohld P | 2000 | Ultrasound Obstet Gynecol2000，16，： | 1 |
| 6 | Spontaneous ectopic tubal pregnancy after laparoscopic tubal sterilisation by segmental isthmic partial salpingectomy显示文摘 | Drakopoulos P Julen O Petignat P | 2014 | BMJ Case Reports2014，，20： | 1 |
| 7 | Diagnosis and management of cervical cancer显示文摘 | Petignat P ROY M | 2007 | BMJ2007，335，7623： | 1 |
| 8 | Pregnancy in a cesarean scar显示文摘 | Vial Y Petignat P Hohlfeld P | 2000 | Ultrasound Obstet Gynecol2000，16，6： | 1 |
| 9 | Pregnancy in a cesarean scar 显示文摘 | Vial Y Petignat P Hohlfeld P | 2000 | Ultrasound Obstet Gyneco12000，16，6： | 1 |
| 10 | Primary screening for cervical cancer precursors by the combined use of liquid-based cytology, computerassisted cytology and HPV DNA testing显示文摘 | Vassilakos P Petignat P Boulvain M | 2002 | Br J Cancer2002，86，3： | 1 |
| 11 | Pregnancy in a cesarean scar ultrasound 显示文摘 | Vial Y Petignat P Hohlfeld P | 2000 | Obstet Gynecol2000，16，： | 1 |
| 12 | Pregnancy in acesaream scar显示文摘 | Yial Y Petignat P Holfeld P | 2000 | Ultrasound Ohset Gynecol2000，16，4： | 1 |
| 13 | Pregnancy in a cesarean scar显示文摘 | Vial Y Petignat P Hohlfeld P | 2000 | Ultrasound Obstet Gynecol2000，16，6： | 1 |
| 14 | Pregnancy in a cesarean scar显示文摘 | Vial Y Petignat P Hohlfeld P | 2000 | Ultrasound Obstet Gynecol2000，16，6： | 1 |
| 15 | Pregnancy in a cesarean scar显示文摘 | VIALY PETIGNAT P HOHLFELD P | | 0，，07： | 1 |
| 16 | Pregnancy in a cesarean scar 显示文摘 | Vial Y Petignat P Hohlfeid P | 2000 | Ultrasound Obstet Gynecol2000，16，6： | 1 |
| 17 | Ovarian cancer therapy : study results from UniversityHospi-tal in the area ofovarian cancer therapy published显示文摘 | Petignat P | 2007 | Clinical Trails Week2007，11，： | 1 |
| 18 | Gynecology显示文摘 | Petignat P Achtari C | 2010 | Rev Med Suisse2010，6，232： | 1 |
| 19 | Pregnancy in a cesarean scar显示文摘 | Vial Y Petignat P Hohlfeld P | 2000 | Ultrasound Obstet Gynecol2000，16，6： | 1 |
| 20 | Pregnancy in a cesarean scar显示文摘 | Vial Y Petignat P Hohlfeid P | 2000 | Ultrasound Obstet Gyneco12000，16，3： | 1 |
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