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| 1 | Recruitment maneuvers in acute respiratory distress syndrome: The safe way is the best way显示文摘Acute respiratory distress syndrome(ARDS) represents a serious problem in critically ill patients and is associated with in-hospital mortality rates of 33%-52%. Recruitment maneuvers(RMs) are a simple, low-cost, feasible intervention that can be performed at the bedside in patients with ARDS. RMs are characterized by the application of airway pressure to increase transpulmonary pressure transiently. Once non-aerated lung units are reopened, improvements are observed in respiratory system mechanics, alveolar reaeration on computed tomography, and improvements in gas exchange(functional recruitment). However, the reopening process could lead to vascular compression, which can be associated with overinflation, and gas exchange may not improve as expected(anatomical recruitment). The purpose of this review was to discuss the effects of different RM strategies- sustained inflation, intermittent sighs, and stepwise increases of positive end-expiratory pressure(PEEP) and/or airway inspiratory pressure- on the following parameters: hemodynamics, oxygenation, barotrauma episodes, and lung recruitability through physiological variables and imaging techniques. RMs and PEEP titration are interdependent events for the success of ventilatory management. PEEP should be adjusted on the basis of respiratory system mechanics and oxygenation. Recent systematic reviews and meta-analyses suggest that RMs are associated with lower mortality in patients with ARDS. However, the optimal RM method(i.e., that providing the best balance of benefit and harm) and the effects of RMs on clinical outcome are still under discussion, and further evidence is needed. | Raquel S Santos Pedro L Silva Paolo Pelosi Patricia RM Rocco | 2015 | World Journal of Critical Care Medicine2015,4,4: | 19 |
| 2 | Effects of positive end-expiratory pressure on regional distribution of tidal volume and recruitment in adult respiratory distress syndrome显示文摘 | Gattinoni L Pelosi P Crotti S | 1995 | Am J Respir Crit Care Med1995,151,6: | 1 |
| 3 | What has computed tomography taught us about the acute respiratory distress syndrome显示文摘 | Gattinoni L Caironi P Pelosi P | 2001 | Am J Re-spirCrit Care Med2001,164,9: | 1 |
| 4 | Diversity of odorant-binding pro- teins and chemosensory proteins in insects 显示文摘 | Pelosi P Calvello M Ban L | 2005 | Chem Senses2005,30,1: | 1 |
| 5 | Pulmonary and extrapulmonary forms of acute respiratory distress syndrome 显示文摘 | PELOSI P CAIRONI P GATTINONI L | 2001 | Respir Crit Care Med2001,22,: | 1 |
| 6 | Lung structure and function in different stage of severe adult respiratory distress syndrome显示文摘 | Bombino M Pelosi P | 1994 | JAMA1994,271,: | 1 |
| 7 | Resuscitation from hemorrhagic shoek: experimental model comparing normal saline, dextran, and hypertonic saline solutions显示文摘 | Chiara O Pelosi P Brazzi L | 2003 | Crit Care Med2003,31,7: | 1 |
| 8 | Effect of positive end-expiratory pressure on regional distribution of tidal volume and recruitment in adult respiratory distress syndrome显示文摘 | Pelosi P Crotti S | 1995 | Am Rev Respir Dis1995,151,: | 1 |
| 9 | Resuscitation from hemorrhagic shock: experimental model comparing normal saline, dextran, and hypertonic saline solutions显示文摘 | Chiara O Pelosi P Brazzi L | 2003 | Crit Care Med2003,31,7: | 1 |
| 10 | Acute respiratory distress syndrome of pulmonary and extra-pulmonary origin:fancy or reality?显示文摘 | Pelosi P Gattinoni L | 2001 | Intensive Care Med2001,27,3: | 1 |
| 11 | Lung structure and function in different stages of severe adult respiratory distress syndrome显示文摘 | Gattinoni L Bombino M Pelosi P | 1994 | JAMA1994,271,: | 1 |
| 12 | Acute respiratory distress syndrome caused by pulmonary and expulmonary disease :different syndrome显示文摘 | Gattinoni L Pelosi P Surer PM | 1998 | Am J Respir Crit Care Med1998,158,: | 1 |
| 13 | Acute respiratory distress syndrome caused by pulmonary and extrapulmonary disease:different syndromes?显示文摘 | Gattinoni L Pelosi P Suter PM | 1998 | Am J Respir Crit Care Med1998,158,: | 1 |
| 14 | Body position changes redistribute lung computed tomographic density in patients with acute respiratory failure显示文摘 | GATTINONI L PELOSI P VITALE G | 1991 | Anesthesiology1991,74,1: | 1 |
| 15 | Working memory dysfunction in major depression: an event-related potential study显示文摘 | PELOSI L SLADE T BLUMHARDT L D | 2000 | Clin Neurophysiol2000,111,: | 1 |
| 16 | A trial of goal-oriented hemodynamic therapy in critically ill patients显示文摘 | Gattinoni L Brazzi L Pelosi P | 1995 | N Engl J Med1995,333,8: | 1 |
| 17 | Prone position in acute respiratory distress syndrome显示文摘 | Brazzi L Gattinoni L | 2002 | Eur Respir J2002,20,: | 1 |
| 18 | Intraoperative motor evoked potentials to transcranial electrical stimulation during two anaesthetic regimens显示文摘 | Pelosi L Stevenson M Hobbs GJ | 2001 | Clin Neurophysiol2001,112,6: | 1 |
| 19 | A trial of goal-oriented hemodynamic therapy in critically ill patients 显示文摘 | Gattinoni L Brazzi L Pelosi P | 1995 | N Engl J Med1995,333,16: | 1 |
| 20 | Soluble proteins in insect chemical communication显示文摘 | Pelosi P Zhou J J Ban L P | 2006 | Cellular and Molecular Life Sciences2006,63,14: | 1 |